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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ASC1
  • cytoplasm
  • telomere maintenance
  • negative regulation of translation
  • molecular_function
  • CBF5
  • box H/ACA snoRNP complex
  • nuclear outer membrane
  • nucleolus
  • rRNA pseudouridine synthesis
  • ribosome biogenesis
  • pseudouridylate synthase activity
  • CDC33
  • nucleus
  • eukaryotic translation initiation factor 4F complex
  • cytoplasm
  • ribosome
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • translational initiation
  • translation initiation factor activity
  • DBP2
  • nucleus
  • cytoplasm
  • mitochondrion
  • nuclear outer membrane
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • RNA helicase activity
  • HEK2
  • cytoplasm
  • nuclear chromosome, telomeric region
  • intracellular mRNA localization
  • telomere maintenance via telomerase
  • mRNA binding
  • HHF1, HHF2
  • nucleus
  • nucleoplasm part
  • nuclear nucleosome
  • chromosome
  • replication fork protection complex
  • chromatin remodeling complex
  • nucleosome
  • histone acetyltransferase complex
  • nucleoplasm
  • histone H3-K79 methylation
  • DNA repair
  • negative regulation of transcription
  • chromatin assembly or disassembly
  • positive regulation of transcription
  • nucleosome assembly
  • DNA binding
  • LHP1
  • nucleus
  • nucleolus
  • nucleoplasm
  • tRNA processing
  • RNA binding
  • MIS1
  • mitochondrion
  • ribosome biogenesis
  • folic acid biosynthetic process
  • anaerobic purine catabolic process
  • nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
  • acetate biosynthetic process from carbon monoxide
  • formate-tetrahydrofolate ligase activity
  • methenyltetrahydrofolate cyclohydrolase activity
  • methylenetetrahydrofolate dehydrogenase (NADP+) activity
  • MRP7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • NAB6
  • cytoplasm
  • RNA metabolic process
  • molecular_function
  • POL2
  • replication fork
  • epsilon DNA polymerase complex
  • lagging strand elongation
  • leading strand elongation
  • nucleotide-excision repair
  • mismatch repair
  • DNA synthesis involved in DNA repair
  • chromatin silencing at telomere
  • nucleotide binding
  • nucleic acid binding
  • DNA binding
  • zinc ion binding
  • DNA-directed DNA polymerase activity
  • nucleotidyltransferase activity
  • metal ion binding
  • double-stranded DNA binding
  • transferase activity
  • PUS7
  • nucleus
  • pseudouridine synthesis
  • snRNA modification
  • ribosome biogenesis
  • tRNA modification
  • pseudouridine synthase activity
  • RBG1
  • cytoplasm
  • ribosome biogenesis
  • GTP binding
  • ROM2
  • cellular bud tip
  • small GTPase mediated signal transduction
  • cellular cell wall organization
  • actin filament organization
  • endocytosis
  • budding cell bud growth
  • response to stress
  • Rho guanyl-nucleotide exchange factor activity
  • signal transducer activity
  • SBP1
  • nuclear outer membrane
  • nucleolus
  • negative regulation of translation in response to stress
  • response to stress
  • snoRNA binding
  • SNP1
  • commitment complex
  • U1 snRNP
  • nuclear mRNA splicing, via spliceosome
  • U1 snRNA binding
  • mRNA binding
  • SRO9
  • polysome
  • ribosome biogenesis
  • translation
  • RNA binding
  • STM1
  • cytoplasm
  • nuclear telomere cap complex
  • anti-apoptosis
  • telomere maintenance
  • DNA binding
  • telomeric DNA binding
  • STO1
  • commitment complex
  • nuclear cap binding complex
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • telomere maintenance
  • nuclear mRNA splicing, via spliceosome
  • mRNA binding
  • SUI3
  • multi-eIF complex
  • ribosome
  • eukaryotic translation initiation factor 2 complex
  • translational initiation
  • translation initiation factor activity
  • TIF1, TIF2
  • plasma membrane enriched fraction
  • eukaryotic translation initiation factor 4F complex
  • cytoplasm
  • ribosome
  • regulation of translation
  • translational initiation
  • regulation of translational initiation
  • translation
  • nucleotide binding
  • nucleic acid binding
  • translation initiation factor activity
  • ATP binding
  • RNA binding
  • ATP-dependent helicase activity
  • helicase activity
  • ATP-dependent RNA helicase activity
  • hydrolase activity
  • TIF4631
  • eukaryotic translation initiation factor 4F complex
  • mitochondrion
  • ribosome
  • ribosome biogenesis
  • translational initiation
  • translation initiation factor activity
  • TIF4632
  • eukaryotic translation initiation factor 4F complex
  • ribosome
  • translational initiation
  • translation initiation factor activity
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • YMR310C
  • nucleus
  • ribosome biogenesis
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    eukaryotic translation initiation factor 4F complex 1.9389E-10 25 4 4 6292
    ribonucleoprotein complex 1.5059E-6 25 514 11 6292
    non-membrane-bounded organelle 2.8548E-6 25 959 14 6292
    intracellular non-membrane-bounded organelle 2.8548E-6 25 959 14 6292
    nuclear outer membrane 3.3058E-4 25 86 4 6292
    nuclear membrane 5.2372E-4 25 97 4 6292
    ribosome 7.6669E-4 25 290 6 6292
    U2-type spliceosomal complex 9.7633E-4 25 12 2 6292
    commitment complex 9.7633E-4 25 12 2 6292
    macromolecular complex 1.3518E-3 25 1635 14 6292
    protein-DNA complex 1.4076E-3 25 57 3 6292
    nuclear part 1.8501E-3 25 1103 11 6292
    nuclear replication fork 2.7564E-3 25 20 2 6292
    nuclear chromosome, telomeric region 3.6437E-3 25 23 2 6292
    plasma membrane enriched fraction 3.9733E-3 25 1 1 6292
    outer membrane 4.9189E-3 25 178 4 6292
    organelle outer membrane 4.9189E-3 25 178 4 6292
    chromosome, telomeric region 5.0062E-3 25 27 2 6292
    nuclear chromosome part 6.1969E-3 25 190 4 6292
    nuclear envelope 7.2899E-3 25 199 4 6292
    box H/ACA snoRNP complex 7.9314E-3 25 2 1 6292
    replication fork protection complex 7.9314E-3 25 2 1 6292
    nucleolus 8.9376E-3 25 211 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    gene expression 3.3494E-7 25 1283 17 6292
    translational initiation 4.9926E-7 25 42 5 6292
    cellular macromolecule metabolic process 1.2762E-6 25 2285 21 6292
    macromolecule metabolic process 2.1531E-6 25 2349 21 6292
    translation 7.6642E-6 25 376 9 6292
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 8.9553E-6 25 11 3 6292
    primary metabolic process 1.5092E-5 25 2896 22 6292
    ribosome biogenesis 3.6535E-5 25 346 8 6292
    cellular metabolic process 3.7393E-5 25 3033 22 6292
    ribonucleoprotein complex biogenesis 6.3869E-5 25 374 8 6292
    metabolic process 8.1439E-5 25 3157 22 6292
    cellular process 1.4853E-4 25 4426 25 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.9715E-4 25 1566 15 6292
    nucleic acid metabolic process 2.7945E-4 25 1415 14 6292
    negative regulation of translation 3.1446E-4 25 7 2 6292
    nuclear-transcribed mRNA catabolic process 4.2654E-4 25 38 3 6292
    pseudouridine synthesis 5.3645E-4 25 9 2 6292
    cellular nitrogen compound metabolic process 8.3774E-4 25 1770 15 6292
    cellular macromolecule biosynthetic process 8.7602E-4 25 1187 12 6292
    macromolecule biosynthetic process 8.8994E-4 25 1189 12 6292
    cellular component biogenesis 9.153E-4 25 694 9 6292
    nitrogen compound metabolic process 9.5963E-4 25 1791 15 6292
    regulation of translation 1.4076E-3 25 57 3 6292
    negative regulation of cellular protein metabolic process 1.5419E-3 25 15 2 6292
    posttranscriptional regulation of gene expression 1.7133E-3 25 61 3 6292
    negative regulation of protein metabolic process 1.7579E-3 25 16 2 6292
    RNA metabolic process 2.2756E-3 25 954 10 6292
    regulation of cellular protein metabolic process 2.3424E-3 25 68 3 6292
    mRNA catabolic process 2.4425E-3 25 69 3 6292
    negative regulation of cellular process 2.63E-3 25 250 5 6292
    negative regulation of biological process 2.7706E-3 25 253 5 6292
    regulation of protein metabolic process 2.9826E-3 25 74 3 6292
    RNA processing 3.0922E-3 25 380 6 6292
    cellular biosynthetic process 3.1916E-3 25 1567 13 6292
    RNA catabolic process 3.7214E-3 25 80 3 6292
    biosynthetic process 3.9351E-3 25 1602 13 6292
    histone H3-K79 methylation 3.9733E-3 25 1 1 6292
    snRNA modification 3.9733E-3 25 1 1 6292
    regulation of translation in response to stress 3.9733E-3 25 1 1 6292
    negative regulation of translation in response to stress 3.9733E-3 25 1 1 6292
    negative regulation of programmed cell death 3.9733E-3 25 1 1 6292
    pteridine and derivative biosynthetic process 3.9733E-3 25 1 1 6292
    negative regulation of cell death 3.9733E-3 25 1 1 6292
    folic acid biosynthetic process 3.9733E-3 25 1 1 6292
    anti-apoptosis 3.9733E-3 25 1 1 6292
    nitrogenous compound catabolic process 3.9733E-3 25 1 1 6292
    negative regulation of apoptosis 3.9733E-3 25 1 1 6292
    anaerobic purine catabolic process 3.9733E-3 25 1 1 6292
    acetate biosynthetic process from carbon monoxide 3.9733E-3 25 1 1 6292
    negative regulation of macromolecule biosynthetic process 4.63E-3 25 175 4 6292
    cellular protein metabolic process 5.5596E-3 25 1074 10 6292
    negative regulation of biosynthetic process 6.0827E-3 25 189 4 6292
    negative regulation of cellular biosynthetic process 6.0827E-3 25 189 4 6292
    negative regulation of macromolecule metabolic process 6.4295E-3 25 192 4 6292
    purine base catabolic process 7.9314E-3 25 2 1 6292
    histone lysine methylation 7.9314E-3 25 2 1 6292
    nucleobase catabolic process 7.9314E-3 25 2 1 6292
    pteridine and derivative metabolic process 7.9314E-3 25 2 1 6292
    folic acid metabolic process 7.9314E-3 25 2 1 6292
    protein metabolic process 8.3636E-3 25 1136 10 6292
    negative regulation of cellular metabolic process 8.6474E-3 25 209 4 6292
    negative regulation of metabolic process 8.7917E-3 25 210 4 6292
    mRNA metabolic process 9.2342E-3 25 213 4 6292
    ncRNA processing 9.5373E-3 25 215 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleic acid binding 2.3951E-9 25 666 15 6292
    translation initiation factor activity 4.9309E-8 25 27 5 6292
    translation factor activity, nucleic acid binding 6.34E-7 25 44 5 6292
    binding 2.8807E-6 25 1294 16 6292
    RNA binding 5.58E-5 25 367 8 6292
    mRNA binding 3.3354E-4 25 35 3 6292
    nucleotide binding 1.5557E-3 25 59 3 6292
    U1 snRNA binding 3.9733E-3 25 1 1 6292
    snoRNA binding 6.5681E-3 25 31 2 6292
    methenyltetrahydrofolate cyclohydrolase activity 7.9314E-3 25 2 1 6292
    methylenetetrahydrofolate dehydrogenase (NADP+) activity 7.9314E-3 25 2 1 6292
    formate-tetrahydrofolate ligase activity 7.9314E-3 25 2 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle