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Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring. Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: methenyltetrahydrofolate cyclohydrolase activity
Acc: GO:0004477
Aspect: Molecular Function
Desc: Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.
Synonyms:
  • citrovorum factor cyclodehydrase activity
  • 5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)
  • 5,10-methenyl-THF cyclohydrolase activity
  • formyl-methenyl-methylenetetrahydrofolate synthetase (combined)
Proteins in PDR annotated with:
   This term: 29 [Search]
   Term or descendants: 29 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004477 - methenyltetrahydrofolate cyclohydrolase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle