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Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids. Any process that stops, prevents or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that stops, prevents or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification. The chemical reactions and pathways by which individual cells transform chemical substances. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of cellular protein metabolic process
Acc: GO:0032269
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
Synonyms:
  • negative regulation of cellular protein metabolism
  • downregulation of cellular protein metabolic process
  • down regulation of cellular protein metabolic process
  • inhibition of cellular protein metabolic process
  • down-regulation of cellular protein metabolic process
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 475 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032269 - negative regulation of cellular protein metabolic process (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle