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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. Any process that stops, prevents or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of protein metabolic process
Acc: GO:0051248
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
Synonyms:
  • down-regulation of protein metabolic process
  • downregulation of protein metabolic process
  • down regulation of protein metabolic process
  • negative regulation of protein metabolism
  • inhibition of protein metabolic process
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 494 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051248 - negative regulation of protein metabolic process (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle