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Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. The cellular metabolic process by which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen. Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress. Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level. Any process that stops, prevents or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of translation in response to stress
Acc: GO:0032055
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.
Synonyms:
  • inhibition of translation in response to stress
  • downregulation of translation in response to stress
  • down-regulation of translation in response to stress
  • down regulation of translation in response to stress
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032055 - negative regulation of translation in response to stress (interactive image map)

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