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Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Any process that stops, prevents or reduces frequency, rate or extent of chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of metabolic process
Acc: GO:0009892
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
Synonyms:
  • inhibition of metabolic process
  • down-regulation of metabolic process
  • downregulation of metabolic process
  • negative regulation of metabolism
  • down regulation of metabolic process
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 2786 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0009892 - negative regulation of metabolic process (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle