Protein Overview: MRP51

General Information:
Name(s) found:	MRP51 / YPL118W [SGD]
Description(s) found: Found 25 descriptions. SHOW ALL	Mitochondrial ribosomal protein of the small subunit; MRP51 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences [SGD]
Organism:	Saccharomyces cerevisiae
Length:	344 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA] mitochondrial small ribosomal subunit [IDA ]
Biological Process:	translational initiation [IMP] translation [IDA ]
Molecular Function:	structural constituent of ribosome [IDA ]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLAELLGRS RIAQVANNHK PLTYTGKKFH PTHQIIETKP STLYRQEWGL KSAIPSKIKS  60
   61 RYLVYNDLDT LERITTFEPR GGTQWNRLRF QEMGVPIVSN IGRQNPFFKY ISRPEDESHA 120
  121 KLSLFKEMKG DTDISPAAMK KRLKKITALI RSFQDEFKEW LVENHPDELK LNSNKLEDYV 180
  181 VKFLNKKLET KTNKKFNTEI IGTGGLSYSL PGKLKNSPNG VIQRTVVPGR ILNVVKENND 240
  241 NKWLAAIGGF VADVVFFQSP PSSFNSMGDF IRMKTFLFEI LEASMEKNGS VSMHARLLEP 300
  301 QNDKTREFFN KRPIYKPLTS RRARRPSVGN IQEANNLLNI IKGN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		EHD3 FYV4 MRP1 MRP13 MRP17 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 SWS2
View Details	(MIPS) Mewes HW, et al. (2004)		MRP1 MRP10 MRP13 MRP17 MRP2 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 PPE1 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 VAR1 YMR31
View Details	Krogan NJ, et al. (2006)		CBF1 FYV4 MAM33 MRP1 MRP10 MRP17 MRP21 MRP4 MRP51 MRPL8 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS9 NAM9 NCL1 PET123 RIB4 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 SVL3 SWS2 YDR124W YJR096W YKL151C YSP1
View Details	Gavin AC, et al. (2006)		EHD3 MRP1 MRP13 MRP17 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS5 MRPS8 MRPS9 NAM9 PET123 RSM10 RSM19 RSM22 RSM23 RSM25 RSM27 RSM7
View Details	Gavin AC, et al. (2002)		BEM2 CCM1 ECM16 EHD3 FYV4 GEP3 HSC82 MRP1 MRP10 MRP13 MRP17 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS5 MRPS8 MRPS9 NAM9 PAP2 PET123 PSD2 PUS7 RIX1 RSM10 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 TIF4631 UBP10 UTP20 UTP22
View Details	Qiu et al. (2008)		EHD3 IMG1 MAM33 MHR1 MNP1 MRP1 MRP10 MRP13 MRP17 MRP2 MRP21 MRP4 MRP49 MRP51 MRP7 MRPL1 MRPL10 MRPL11 MRPL13 MRPL15 MRPL16 MRPL17 MRPL19 MRPL20 MRPL22 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL31 MRPL32 MRPL33 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL40 MRPL44 MRPL49 MRPL50 MRPL51 MRPL6 MRPL7 MRPL8 MRPL9 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 PPE1 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 SWS2 VAR1 YDR115W YML6 YMR31

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 2- cpn2 from june 2005	McCusker D, et al (2007)
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	YIF1	MRP51	1	Unpublished Fields Lab Data
View Screen	HRT1	MRP51	1	Unpublished Fields Lab Data
View Screen	ILM1	MRP51	1	Lockshon D, et al. (2006)

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	MRP51	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..101]	MSA	2.006983	View MSA. No confident structure predictions are available.
2	View Details	[102..344]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2