Protein Overview: DOG1

General Information:
Name(s) found:	DOG1 / YHR044C [SGD]
Description(s) found: Found 27 descriptions. SHOW ALL	2-deoxyglucose-6-phosphate phosphatase, similar to Dog2p, member of a family of low molecular weight phosphatases; confers 2-deoxyglucose resistance when overexpressed, in vivo substrate has not yet been identified [SGD]
Organism:	Saccharomyces cerevisiae
Length:	246 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	glucose metabolic process [ISS]
Molecular Function:	2-deoxyglucose-6-phosphatase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEFSADLCL FDLDGTIVST TVAAEKAWTK LCYEYGVDPS ELFKHSHGAR TQEVLRRFFP  60
   61 KLDDTDNKGV LALEKDIAHS YLDTVSLIPG AENLLLSLDV DTETQKKLPE RKWAIVTSGS 120
  121 PYLAFSWFET ILKNVGKPKV FITGFDVKNG KPDPEGYSRA RDLLRQDLQL TGKQDLKYVV 180
  181 FEDAPVGIKA GKAMGAITVG ITSSYDKSVL FDAGADYVVC DLTQVSVVKN NENGIVIQVN 240
  241 NPLTRA

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		BUD14 CDC12 CIA1 CMP2 COR1 DOG1 DOG2 ENP1 FET4 FPR3 GIS4 GUS1 HAS1 HSP104 IMD4 KEL1 KEL2 KIN2 KRE6 MAM33 MDY2 MET18 MET6 MSK1 PIM1 POP2 PRP8 PYC1 QCR2 RGD1 RPN8 SAP185 SAP190 SEC53 SIT4 SNP1 SRP1 TEF4 TFC4 TMA19 UBA1 UBP9 VAC14 VMA22

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	MLP2	#29 Asynchronous Prep5-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MIG1	DOG1	1	Unpublished Fields Lab Data
View Screen	SPT21	DOG1	1	Unpublished Fields Lab Data
View Screen	FRQ1	DOG1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..20] [79..246]	PSI-BLAST	27.69897	L-2-Haloacid dehalogenase, HAD
2	View Details	[21..78]	PSI-BLAST	27.69897	L-2-Haloacid dehalogenase, HAD

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2