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Protein Overview: PIH1

General Information:
Name(s) found: PIH1 / YHR034C [SGD]
Description(s) found:
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  • gi|731647|sp|P38768.1|PIH1_YEAST RecName: Full=Protein interacting with Hsp90 1; AltName: Full=Nucleolar protein 17 [NCBI NR]
  • gi|6321823|ref|NP_011899.1| Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p); Pih1 [NCBI NR]
  • pir||S46745 hypothetical protein YHR034c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|488179|gb|AAB68914.1| Yhr034cp [Saccharomyces cerevisiae] [NCBI NR]
  • (P38768) Hypothetical 39.5 kDa protein in SLT2-PUT2 intergenic region [Swiss-Prot]
  • Protein interacting with Hsp90 1 OS=Saccharomyces cerevisiae GN=PIH1 PE=1 SV=1 [Swiss-Prot]
  • PIH1 Protein with a role in pre-rRNA processing [mips]
  • Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p) [SGD]
  • YHR034C, Chr VIII from 176956-177990, reverse complement [yeast_orfs2]
  • Chr VIII from 176956-177990, reverse complement [yeastorf3.fasta]
  • Chr VIII from 177990-176956, reverse complement [yeastorf5.fasta]
  • PIH1 SGDID:S0001076, Chr VIII from 177991-176957, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • Pih1p [Saccharomyces cerevisiae]gi|731647|sp|P38768|YHJ4_YEAST Hypothetical 39.5 kDa protein in SLT2-PUT2 intergenic regiongi|488179|gb|AAB68914.1| Yhr034cp [Saccharomyces cerevisiae]gi|626604|pir||S46745 hypothetical protein YHR034c - yeast (Saccharom [nrdb_11152004_Chlamydomonas]
  • PIH1 SGDID:S000001076, Chr VIII from 177992-176958, reverse complement, Verified ORF, "Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rv [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Protein interacting with Hsp90 1 (Nucleolar protein 17) [nr-271106-contam.fasta]
  • Yhr034cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p); Pih1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • PIH1 SGDID:S000001076, Chr VIII from 177992-176958, reverse complement, Verified ORF, "Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p)" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Protein interacting with Hsp90 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PIH1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • PIH1 SGDID:S000001076, Chr VIII from 177999-176965, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p)" [yeast-030211-contam.fasta]
  • PIH1 SGDID:S000001076, Chr VIII from 177999-176965, Genome Release 64-2-1, reverse complement, Verified ORF, "Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90 (Hsp82p and Hsc82p) to mediate assembly large protein complexes such as box C/D snoRNPs and RNA polymerase II" [20141208_orf_trans.fasta]
  • YHR034C SGDID:S000001076, Chr VIII from 177999-176965, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p)" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 344 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    small nucleolar ribonucleoprotein complex [IPILink to PubMed article]
    Biological Process: regulation of cell size [IMPLink to PubMed article]
    rRNA processing [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    protein folding [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADFLLRPIK QRHRNEDKYV SVDAADGSVS KIEPIADFVI KTKLLSANGP EKLQDGRKVF  60
   61 INVCHSPLVP KPEVDFNARI VFPLIIQNEW EIPIITSCYR MDHDKKGQEC YVWDCCINSD 120
  121 CSRWICDDIQ LREILVEWCL ESCEIRDSVV LCRDRIAFPK MKKKGAELPA LEVLNDELHQ 180
  181 DYKAKMHKII EEEAGDPMSI LRGRNDDGDD NNDPDDGTLP PLFPIENKIS GAKIEEIDKN 240
  241 EIAHRNLKQA PAPAPAPHEQ QEDVPEYEVK MKRFKGAAYK LRILIENKAP NSKPDRFSPS 300
  301 YNFAENILYI NGKLSIPLPR DIVVNAADIK IFHIRKERTL YIYI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) PIH1 RVB1 RVB2 TAH1
    View Details Krogan NJ, et al. (2006) ARP4 ARP5 ARP6 ARP8 CCA1 EAF1 EAF5 EAF6 EAF7 EPL1 ESA1 IES1 IES2 IES3 IES4 IES5 IES6 INO80 NHP10 NTO1 PIH1 RVB1 RVB2 SAS3 SWC3 SWC4 SWC5 SWC7 SWR1 TAH1 TRA1 VPS71 VPS72 YAF9 YNG2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PIH1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..204] MSA 6.008969 View MSA. No confident structure predictions are available.
    2 View Details [205..344] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle