YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: HOR2

General Information:
Name(s) found: HOR2 / YER062C [SGD]
Description(s) found:
Found 29 descriptions.
SHOW ALL
  • One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol biosynthesis; induced in response to hyperosmotic stress and oxidative stress, and during the diauxic transition [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 250 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: carbohydrate metabolic process [IDALink to PubMed article]
    response to osmotic stress [IDALink to PubMed article]
    glycerol biosynthetic process [IMPLink to PubMed article]
    Molecular Function: glycerol-1-phosphatase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLTTKPLSL KVNAALFDVD GTIIISQPAI AAFWRDFGKD KPYFDAEHVI QVSHGWRTFD  60
   61 AIAKFAPDFA NEEYVNKLEA EIPVKYGEKS IEVPGAVKLC NALNALPKEK WAVATSGTRD 120
  121 MAQKWFEHLG IRRPKYFITA NDVKQGKPHP EPYLKGRNGL GYPINEQDPS KSKVVVFEDA 180
  181 PAGIAAGKAA GCKIIGIATT FDLDFLKEKG CDIIVKNHES IRVGGYNAET DEVEFIFDDY 240
  241 LYAKDDLLKW

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HCH1 HOR2 LIF1 PIG2 YBR139W YKL069W
    View Details Ho Y, et al. (2002) AAC3 ACO1 AHA1 ARO1 ATP3 BEM2 CCL1 CYS4 DUN1 ECM10 GCD11 GPH1 HEF3 HOM3 HOR2 HXT6 HXT7 ILV2 LSC1 MET18 MTC5 NAT1 OYE2 PFK1 PGM2 PIL1 PRB1 PTC3 RAD3 RAD52 RAD59 RFA3 RHR2 RNQ1 RPN1 RPT3 SEC27 SEC53 SML1 TEF4 TFP1 THI22 UBA1 VMA8 YER138C YJR141W YPT31
    View Details Qiu et al. (2008) HOR2 RHR2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data HOR2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..27]
    [86..250]    		 PSI-BLAST 20.0 L-2-Haloacid dehalogenase, HAD
    2 View Details [28..85] PSI-BLAST 20.0 L-2-Haloacid dehalogenase, HAD


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle