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Protein Overview: DIG2

General Information:
Name(s) found: DIG2 / YDR480W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: nucleus [TASLink to PubMed article]
    Biological Process: invasive growth in response to glucose limitation [IGILink to PubMed article]
    Molecular Function: transcription factor binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKEEQEDPQ QEQISTVQEN DPRNLQQLGM LLVSPGLDED RLSEKMISKI KKSRDIEKNQ  60
   61 KLLISRLSQK EEDHSGKPPT ITTSPAEKTV PFKSLNHSLK RKRVPPALNF SDIQASSHLH 120
  121 GSKSAPPNIT RFPQHKNSLR VRYMGRMAPT NQDYHPSVAN SYMTATYPYP YTGLPPVPCY 180
  181 PYSSTPTQTH AYEGYYSPMY PGPLYNNGII PADYHAKRKK LAGRSPHLED LTSRKRTFVS 240
  241 KHHNGDPIIS KTDEDIECSV TKNSLSEGAS LNDDADDDND KERIIIGEIS LYDDVFKFEV 300
  301 RDDKNDYMKA CETIWTEWHN LKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) DIG1 DIG2 KSS1 STE12
    View Details Krogan NJ, et al. (2006) AHA1 BUD3 CNS1 CPR6 DIG2 DNM1 DSF1, YNR073C FRT2 GPA2 HOM6 HSC82 HSP104 HSP82 MBB1 MRPL50 PAM1 PPT1 QNS1 RMD8 RTS1 SMT3 STI1 STP4 TDH1 UTP20 YBL104C
    View Details Ho Y, et al. (2002) ACO1 ARP7 AVO1 BEM3 CCT2 CYS4 DIG1 DIG2 FET4 GFA1 GUS1 HAS1 HXT6 KSS1 MKT1 MSE1 NAP1 NPA3 PHO84 PIM1 PMA1 PYC1 RGC1 RPA135 RPN10 RPN6 RVB1 SEN1 SRP1 STE11 STE12 STE7 TEC1 TSC11 UBI4 YDR239C YHR033W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NUP2 DIG2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data DIG2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..323] deduced N/A No confident structure predictions are available.
    2 View Details [174..323] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle