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View Structure Prediction Details

Protein: AB12C_ARATH
Organism: Arabidopsis thaliana
Length: 1495 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AB12C_ARATH.

Description E-value Query
Range		 Subject
Range
gi|29893528 - gi|29893528|gb|AAN65348.1| multidrug resistance protein 1A [Macaca fascicularis]
 1119.0 [0..5] [1472..2]

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Predicted Domain #1
Region A:
Residues: [1-133] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFEALNWYC KPVADGFWEK AVDGAFGAYT PCAIDSLVML VSHFVLLGLC FYRIWIIFHN  60
   61 TKAQIYVLRK KYYNCVLGLL ACYCVVEPVL RLVMGISLFD MDEETDFPPF EVASLMVEAF 120
  121 AWFSMLVLIG LET

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [134-267] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQYVKEFRWY VRFGVLYVLV ADAVLLDLVL PLKNSINRTA LYLFISSRCS QALFGILLLI  60
   61 YIPELDPYPG YHIVNNEPLD NVEYDALRGG EHICPERHAS IFSRIYFGWI TPLMQLGYRK 120
  121 PITEKDVWQL DKWD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [268-611] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTETLIKRFQ RCWTEESRRP KPWLLRALNN SLGGRFWLAG IFKIGNDLSQ FVGPVILSHL  60
   61 LRSMQEGDPA WVGYVYAFII FVGVTLGVLC EAQYFQNVWR VGFRLRSTLV AAIFHKSLRL 120
  121 THEARKNFAS GKVTNMITTD ANALQQISQQ LHGLWSAPFR IIVSMILLYQ QLGVASLFGS 180
  181 LILFLLIPLQ TLIISKMRKL TKEGLQWTDK RVGITNEILS SMDTVKCYAW EKSFESRIQG 240
  241 IRNEELSWFR KAQLLSAFNS FILNSIPVVV TVVSFGVFVL LGGDLTPARA FTSLSLFAVL 300
  301 RFPLNMLPNL LSQVVNANVS LQRIEELLLS EERILAQNPP LQPG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.07
Match: 2hydA
Description: No description for 2hydA was found.

Predicted functions:

Term Confidence Notes
lipid transporter activity 6.95325922226092 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 5.4467861893359 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 5.44654566127945 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 5.44654566127945 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 5.43909190876515 bayes_pls_golite062009
primary active transmembrane transporter activity 5.4304944906989 bayes_pls_golite062009
active transmembrane transporter activity 5.38112407181712 bayes_pls_golite062009
ATPase activity, coupled 4.87869064889244 bayes_pls_golite062009
ATPase activity 4.60773943958528 bayes_pls_golite062009
nucleoside-triphosphatase activity 4.38591214726007 bayes_pls_golite062009
pyrophosphatase activity 4.32673473878039 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 4.31087891816858 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.31037981322306 bayes_pls_golite062009
hydrolase activity 4.09315408758191 bayes_pls_golite062009
transporter activity 3.47953169973151 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.96171085039592 bayes_pls_golite062009
transmembrane transporter activity 2.94175800357966 bayes_pls_golite062009
substrate-specific transporter activity 2.90743799425416 bayes_pls_golite062009
ATP binding 2.83986218503994 bayes_pls_golite062009
adenyl ribonucleotide binding 2.79195527951815 bayes_pls_golite062009
adenyl nucleotide binding 2.74359323245512 bayes_pls_golite062009
purine ribonucleotide binding 2.55506944753783 bayes_pls_golite062009
ribonucleotide binding 2.55426312645972 bayes_pls_golite062009
purine nucleotide binding 2.51344800975739 bayes_pls_golite062009
nucleotide binding 2.48057252852174 bayes_pls_golite062009
binding 1.81483350844459 bayes_pls_golite062009
catalytic activity 0.372934161904337 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [612-894] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPAISIKNGY FSWDSKTTKP TLSDINLEIP VGTLVAIVGG TGEGKTSLIS AMLGELSHAE  60
   61 TTSVVIRGSV AYVPQVSWIF NATVRENILF GSDFESERYW RAIDATALQH DLDLLPGRDL 120
  121 TEIGERGVNI SGGQKQRVSM ARAVYSNSDV YIFDDPLSAL DAHVAHQVFD SCMKDELRGK 180
  181 TRVLVTNQLH FLPLMDKIIL VSEGMIKEEG TFVELSKSGI LFKKLMENAG KMDATQEVNT 240
  241 NDENILKLGP TVTVDVSERN LGSTKQGKRR RSVLIKQEER ETG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.39794
Match: 2cbzA
Description: No description for 2cbzA was found.

Predicted Domain #5
Region A:
Residues: [895-1495] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IISWNVLMRY KEAVGGLWVV MILLACYLAT EVLRVSSSTW LSIWTDQSTS KNYSPGFYIV  60
   61 VYALLGFGQV AVTFTNSFWL ITSSLHAARR LHDAMLSSIL RAPMLFFHTN PTGRVINRFS 120
  121 KDIGDIDRNV ANLMNMFMNQ LWQLLSTFAL IGTVSTISLW AIMPLLILFY AAYLYYQSTS 180
  181 REVRRLDSVT RSPIYAQFGE ALNGLSSIRA YKAYDRMAKI NGKSMDNNIR FTLANTSSNR 240
  241 WLTIRLETLG GVMIWLTATF AVLQNGNTNN QAGFASTMGL LLSYTLNITS LLSGVLRQAS 300
  301 RAENSLNSVE RVGNYIDLPS EATDIIENNR PVCGWPSGGS IKFEDVHLRY RPGLPPVLHG 360
  361 LTFFVSPSEK VGVVGRTGAG KSSMLNALFR IVEVEKGRIM IDDCDVAKFG LTDVRRVLSI 420
  421 IPQSPVLFSG TVRFNIDPFS EHNDAGLWEA LHRAHIKDVI SRNPFGLDAE VCEGGENFSV 480
  481 GQRQLLSLAR ALLRRSKILV LDEATASVDV RTDSLIQRTI REEFKSCTML VIAHRLNTII 540
  541 DCDKILVLSS GQVLEYDSPQ ELLSRDTSAF FRMVHSTGPA NAQYLSNLVF ERRENGMSVG 600
  601 G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 134.0
Match: 2hydA
Description: No description for 2hydA was found.

Predicted functions:

Term Confidence Notes
lipid transporter activity 7.47642599298853 bayes_pls_golite062009
metal ion transmembrane transporter activity 6.80339337010085 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 5.57844095962502 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 5.57813579764186 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 5.57813579764186 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 5.5689620139321 bayes_pls_golite062009
primary active transmembrane transporter activity 5.55992639965745 bayes_pls_golite062009
active transmembrane transporter activity 5.50005167063544 bayes_pls_golite062009
cation channel activity 5.46287131955314 bayes_pls_golite062009
voltage-gated cation channel activity 5.29074477899638 bayes_pls_golite062009
voltage-gated ion channel activity 5.1184221202951 bayes_pls_golite062009
potassium channel activity 5.11125652739479 bayes_pls_golite062009
voltage-gated channel activity 5.10064970232011 bayes_pls_golite062009
ATPase activity, coupled 4.98276715440477 bayes_pls_golite062009
ion channel activity 4.87468443062464 bayes_pls_golite062009
channel activity 4.74517495695421 bayes_pls_golite062009
passive transmembrane transporter activity 4.74517495695421 bayes_pls_golite062009
peptide transporter activity 4.7442815698413 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 4.71935767060308 bayes_pls_golite062009
substrate-specific channel activity 4.71152823189573 bayes_pls_golite062009
ATPase activity 4.69795387297193 bayes_pls_golite062009
peptide-transporting ATPase activity 4.63590351019108 bayes_pls_golite062009
cadmium ion transmembrane transporter activity 4.62439240790153 bayes_pls_golite062009
gated channel activity 4.61941650351493 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 4.45975815173802 bayes_pls_golite062009
nucleoside-triphosphatase activity 4.45923622153365 bayes_pls_golite062009
pyrophosphatase activity 4.39781350157199 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 4.38133275795019 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.38085303582726 bayes_pls_golite062009
sulfonylurea receptor activity 4.29224907929661 bayes_pls_golite062009
bilirubin transmembrane transporter activity 4.16465937144981 bayes_pls_golite062009
hydrolase activity 4.12107348093071 bayes_pls_golite062009
oligopeptide-transporting ATPase activity 4.09365342567844 bayes_pls_golite062009
transporter activity 3.71239480053329 bayes_pls_golite062009
ion transmembrane transporter activity 3.35436118751376 bayes_pls_golite062009
phosphate transmembrane-transporting ATPase activity 3.20894563245332 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 3.16975154423199 bayes_pls_golite062009
transmembrane transporter activity 3.13960906549884 bayes_pls_golite062009
anion transmembrane transporter activity 3.13913638619234 bayes_pls_golite062009
substrate-specific transporter activity 3.1318898376276 bayes_pls_golite062009
cation transmembrane transporter activity 3.08390071341252 bayes_pls_golite062009
iron ion transmembrane transporter activity 3.05511942104215 bayes_pls_golite062009
ATP binding 3.01346604299372 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.00745742755195 bayes_pls_golite062009
drug transmembrane transporter activity 2.97119034312001 bayes_pls_golite062009
adenyl ribonucleotide binding 2.96271391116269 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 2.9271291809464 bayes_pls_golite062009
adenyl nucleotide binding 2.91131545957759 bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity 2.88795687640992 bayes_pls_golite062009
ligand-gated ion channel activity 2.77610331510393 bayes_pls_golite062009
ligand-gated channel activity 2.77610331510393 bayes_pls_golite062009
purine ribonucleotide binding 2.70262534541085 bayes_pls_golite062009
ribonucleotide binding 2.70178191749524 bayes_pls_golite062009
amine-transporting ATPase activity 2.69529191205818 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.67957846350199 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 2.67815672695824 bayes_pls_golite062009
purine nucleotide binding 2.6583477492092 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 2.63419811368692 bayes_pls_golite062009
nucleotide binding 2.62374702628143 bayes_pls_golite062009
sterol transporter activity 2.48473697371886 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.40292717311506 bayes_pls_golite062009
canalicular bile acid transmembrane transporter activity 2.33958437214304 bayes_pls_golite062009
amine transmembrane transporter activity 2.29486577878686 bayes_pls_golite062009
structural constituent of muscle 2.27871582090443 bayes_pls_golite062009
2.20174656498665 bayes_pls_golite062009
phosphate transmembrane transporter activity 2.15147988861177 bayes_pls_golite062009
oligopeptide transporter activity 2.05580564974083 bayes_pls_golite062009
L-aspartate transmembrane transporter activity 2.05274761921715 bayes_pls_golite062009
voltage-gated calcium channel activity 1.96314034513078 bayes_pls_golite062009
binding 1.84115074893083 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 1.82177108193332 bayes_pls_golite062009
organic anion transmembrane transporter activity 1.76999970080179 bayes_pls_golite062009
motor activity 1.64238426331767 bayes_pls_golite062009
amino acid transmembrane transporter activity 1.59627719545436 bayes_pls_golite062009
nucleic acid binding 1.52921795164482 bayes_pls_golite062009
phosphonate transmembrane transporter activity 1.40269234722336 bayes_pls_golite062009
monocarboxylic acid transmembrane transporter activity 1.37836402136387 bayes_pls_golite062009
glutathione transmembrane transporter activity 1.35514937365621 bayes_pls_golite062009
sphingolipid transporter activity 1.35514937365621 bayes_pls_golite062009
manganese ion transmembrane transporter activity 1.34412762758893 bayes_pls_golite062009
molybdate ion transmembrane transporter activity 1.28313088935613 bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity 1.28313088935613 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.23799860254751 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
DNA binding 1.19966224604123 bayes_pls_golite062009
peptidase activity 1.12876670227791 bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity 1.1220946941463 bayes_pls_golite062009
nucleotide kinase activity 1.10251779925246 bayes_pls_golite062009
transcription regulator activity 1.09075553688438 bayes_pls_golite062009
manganese-transporting ATPase activity 1.05250190312265 bayes_pls_golite062009
protein transporter activity 1.05248757342537 bayes_pls_golite062009
dipeptide transporter activity 1.01130176523309 bayes_pls_golite062009
signal transducer activity 0.952448314982579 bayes_pls_golite062009
molecular transducer activity 0.952448314982579 bayes_pls_golite062009
cytoskeletal protein binding 0.933937517908868 bayes_pls_golite062009
0.869999622006359 bayes_pls_golite062009
structural constituent of ribosome 0.860102064846772 bayes_pls_golite062009
GTPase activity 0.83849854735032 bayes_pls_golite062009
signal recognition particle binding 0.834762947727611 bayes_pls_golite062009
copper ion transmembrane transporter activity 0.798934081014025 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.767424210804186 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.765442336337003 bayes_pls_golite062009
phospholipid transporter activity 0.755445322666929 bayes_pls_golite062009
microfilament motor activity 0.723407201613229 bayes_pls_golite062009
glutathione S-conjugate-exporting ATPase activity 0.719430645205088 bayes_pls_golite062009
bile acid transmembrane transporter activity 0.687612064139871 bayes_pls_golite062009
high voltage-gated calcium channel activity 0.64930610472341 bayes_pls_golite062009
cholesterol transporter activity 0.644421039250979 bayes_pls_golite062009
actin binding 0.563996324417607 bayes_pls_golite062009
long-chain fatty acid transporter activity 0.445784480190949 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 0.40217318916177 bayes_pls_golite062009
catalytic activity 0.368034275052766 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
receptor activity 0.277332279568238 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
fatty acid transporter activity 0.251070374183928 bayes_pls_golite062009
transmembrane receptor activity 0.243026482777117 bayes_pls_golite062009
neutral amino acid transmembrane transporter activity 0.227570438294493 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 0.219473333671469 bayes_pls_golite062009
apolipoprotein receptor activity 0.201503131198139 bayes_pls_golite062009
syntaxin-13 binding 0.201503131198139 bayes_pls_golite062009
apolipoprotein A-I binding 0.201503131198139 bayes_pls_golite062009
apolipoprotein A-I receptor activity 0.201503131198139 bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity 0.175442402308287 bayes_pls_golite062009
amino acid-transporting ATPase activity 0.147644650870465 bayes_pls_golite062009
structural molecule activity 0.11239762372728 bayes_pls_golite062009
sulfate transmembrane transporter activity 0.104477131120205 bayes_pls_golite062009
transcription factor activity 0.0612932659603008 bayes_pls_golite062009
cation-transporting ATPase activity 0.0536898657672154 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle