From Publication: | Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3. |
Notes: | This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Sec27. The topolgies of protein complexes in this experiment are unknown. |
Complex Size: | 19 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
COPI coated vesicle membrane | 1.9392E-6 | 19 | 9 | 3 | 6292 |
COPI vesicle coat | 1.9392E-6 | 19 | 9 | 3 | 6292 |
chaperonin-containing T-complex | 5.0498E-6 | 19 | 12 | 3 | 6292 |
Golgi-associated vesicle membrane | 1.2756E-5 | 19 | 16 | 3 | 6292 |
COPI-coated vesicle | 3.0008E-5 | 19 | 21 | 3 | 6292 |
vesicle coat | 1.317E-4 | 19 | 34 | 3 | 6292 |
coated vesicle membrane | 1.4377E-4 | 19 | 35 | 3 | 6292 |
cytoplasmic vesicle membrane | 1.4377E-4 | 19 | 35 | 3 | 6292 |
vesicle membrane | 1.4377E-4 | 19 | 35 | 3 | 6292 |
membrane coat | 1.8426E-4 | 19 | 38 | 3 | 6292 |
coated membrane | 1.8426E-4 | 19 | 38 | 3 | 6292 |
cytoplasmic vesicle part | 1.9923E-4 | 19 | 39 | 3 | 6292 |
Golgi-associated vesicle | 2.1497E-4 | 19 | 40 | 3 | 6292 |
Golgi membrane | 3.9405E-4 | 19 | 49 | 3 | 6292 |
coated vesicle | 1.8416E-3 | 19 | 83 | 3 | 6292 |
late endosome | 1.9252E-3 | 19 | 22 | 2 | 6292 |
proteasome regulatory particle | 2.1048E-3 | 19 | 23 | 2 | 6292 |
proteasome accessory complex | 2.1048E-3 | 19 | 23 | 2 | 6292 |
endosome | 2.6308E-3 | 19 | 94 | 3 | 6292 |
protein complex | 3.2286E-3 | 19 | 1137 | 9 | 6292 |
membrane-bounded vesicle | 3.8001E-3 | 19 | 107 | 3 | 6292 |
cytoplasmic vesicle | 3.8001E-3 | 19 | 107 | 3 | 6292 |
cytoplasmic membrane-bounded vesicle | 3.8001E-3 | 19 | 107 | 3 | 6292 |
vesicle | 4.1084E-3 | 19 | 110 | 3 | 6292 |
Golgi apparatus part | 5.1237E-3 | 19 | 119 | 3 | 6292 |
cytosolic part | 5.493E-3 | 19 | 122 | 3 | 6292 |
proteasome complex | 8.972E-3 | 19 | 48 | 2 | 6292 |
mRNA cap binding complex | 9.0332E-3 | 19 | 3 | 1 | 6292 |
cytosol | 9.2018E-3 | 19 | 284 | 4 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
protein folding | 7.3552E-5 | 19 | 78 | 4 | 6292 |
catabolic process | 3.9532E-4 | 19 | 496 | 7 | 6292 |
cellular catabolic process | 1.0295E-3 | 19 | 415 | 6 | 6292 |
ER to Golgi vesicle-mediated transport | 1.8416E-3 | 19 | 83 | 3 | 6292 |
retrograde vesicle-mediated transport, Golgi to ER | 2.6892E-3 | 19 | 26 | 2 | 6292 |
regulation of pH | 3.3414E-3 | 19 | 29 | 2 | 6292 |
monovalent inorganic cation homeostasis | 5.6929E-3 | 19 | 38 | 2 | 6292 |
cellular macromolecule catabolic process | 7.2256E-3 | 19 | 265 | 4 | 6292 |
cellular protein metabolic process | 9.0272E-3 | 19 | 1074 | 8 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
unfolded protein binding | 7.523E-4 | 19 | 61 | 3 | 6292 |
protein binding | 1.4116E-3 | 19 | 612 | 7 | 6292 |
chaperone inhibitor activity | 3.0197E-3 | 19 | 1 | 1 | 6292 |
UTP:galactose-1-phosphate uridylyltransferase activity | 3.0197E-3 | 19 | 1 | 1 | 6292 |
eukaryotic initiation factor 4E binding | 3.0197E-3 | 19 | 1 | 1 | 6292 |
translation initiation factor binding | 3.0197E-3 | 19 | 1 | 1 | 6292 |
Hsp70 protein binding | 6.0308E-3 | 19 | 2 | 1 | 6292 |
UTP-monosaccharide-1-phosphate uridylyltransferase activity | 6.0308E-3 | 19 | 2 | 1 | 6292 |
isocitrate dehydrogenase (NAD+) activity | 6.0308E-3 | 19 | 2 | 1 | 6292 |
Hsp90 protein binding | 6.0308E-3 | 19 | 2 | 1 | 6292 |
chaperone activator activity | 9.0332E-3 | 19 | 3 | 1 | 6292 |
uridylyltransferase activity | 9.0332E-3 | 19 | 3 | 1 | 6292 |
heat shock protein binding | 9.0332E-3 | 19 | 3 | 1 | 6292 |
copper uptake transmembrane transporter activity | 9.0332E-3 | 19 | 3 | 1 | 6292 |