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A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. A complex in eukaryotic cells containing Mapbpip (p14,Rab25) and Map2k1ip1 (MP1). The complex anchors on late endosomes and is involved in activating ERK 1/2, key components in MAPK signaling. The lipid bilayer surrounding an organelle. The lipid bilayer surrounding a late endosome. The lipid bilayer surrounding a multivesicular body. Any constituent part of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation. The lipid bilayer surrounding an endosome. A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: late endosome membrane
Acc: GO:0031902
Aspect: Cellular Component
Desc: The lipid bilayer surrounding a late endosome.
Proteins in PDR annotated with:
   This term: 40 [Search]
   Term or descendants: 43 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031902 - late endosome membrane (interactive image map)

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