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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Glc7. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FIN1
  • nucleus
  • spindle pole body
  • spindle
  • intermediate filament
  • astral microtubule
  • mitotic sister chromatid segregation
  • intermediate filament-based process
  • mitotic spindle stabilization
  • structural constituent of cytoskeleton
  • microtubule binding
  • FPR3
  • nucleolus
  • meiotic recombination checkpoint
  • peptidyl-prolyl cis-trans isomerase activity
  • GLC7
  • protein phosphatase type 1 complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • cellular bud neck
  • spindle pole body
  • nuclear outer membrane
  • nucleolus
  • mating projection base
  • mitotic cell cycle spindle assembly checkpoint
  • cell morphogenesis during vegetative growth
  • protein amino acid dephosphorylation
  • chromosome segregation
  • cell budding
  • cellular ion homeostasis
  • meiosis
  • regulation of carbohydrate metabolic process
  • ascospore formation
  • response to heat
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • glycogen metabolic process
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone dephosphorylation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • RNA binding
  • metal ion binding
  • hydrolase activity
  • GLC8
  • nucleus
  • cytoplasm
  • glycogen biosynthetic process
  • chromosome segregation
  • enzyme activator activity
  • GSY1
  • cytoplasm
  • mitochondrion
  • glycogen biosynthetic process
  • glycogen (starch) synthase activity
  • NOP7
  • nucleus
  • nucleolus
  • cell proliferation
  • maturation of SSU-rRNA
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • cell cycle
  • molecular_function
  • REG1
  • protein phosphatase type 1 complex
  • cytoplasm
  • negative regulation of transcription from RNA polymerase II promoter
  • regulation of carbohydrate metabolic process
  • glycogen metabolic process
  • vacuolar protein catabolic process
  • protein phosphatase type 1 regulator activity
  • SDS22
  • nucleus
  • cytoplasm
  • protein targeting
  • chromosome segregation
  • protein phosphatase type 1 regulator activity
  • enzyme regulator activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 1 complex 2.9615E-5 8 7 2 6292
    protein serine/threonine phosphatase complex 1.9058E-4 8 17 2 6292
    astral microtubule 1.2715E-3 8 1 1 6292
    aster 1.2715E-3 8 1 1 6292
    nucleolus 1.8378E-3 8 211 3 6292
    intermediate filament 2.5415E-3 8 2 1 6292
    intermediate filament cytoskeleton 2.5415E-3 8 2 1 6292
    microtubule organizing center 2.6577E-3 8 63 2 6292
    spindle pole body 2.6577E-3 8 63 2 6292
    spindle pole 3.0901E-3 8 68 2 6292
    spindle 5.2414E-3 8 89 2 6292
    microtubule cytoskeleton 7.3681E-3 8 106 2 6292
    mating projection base 8.8705E-3 8 7 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    glycogen metabolic process 3.8035E-8 8 32 4 6292
    energy reserve metabolic process 3.8035E-8 8 32 4 6292
    cellular glucan metabolic process 1.298E-7 8 43 4 6292
    glucan metabolic process 1.298E-7 8 43 4 6292
    cellular polysaccharide metabolic process 3.5652E-7 8 55 4 6292
    polysaccharide metabolic process 5.0845E-7 8 60 4 6292
    glucose metabolic process 5.6565E-6 8 109 4 6292
    hexose metabolic process 9.4651E-6 8 124 4 6292
    chromosome segregation 1.0741E-5 8 128 4 6292
    monosaccharide metabolic process 1.3275E-5 8 135 4 6292
    energy derivation by oxidation of organic compounds 1.9641E-5 8 149 4 6292
    generation of precursor metabolites and energy 5.6804E-5 8 195 4 6292
    alcohol metabolic process 9.1161E-5 8 220 4 6292
    regulation of cell cycle process 1.0989E-4 8 81 3 6292
    glycogen biosynthetic process 1.4733E-4 8 15 2 6292
    negative regulation of cellular process 1.5014E-4 8 250 4 6292
    negative regulation of biological process 1.5728E-4 8 253 4 6292
    cellular carbohydrate metabolic process 1.8018E-4 8 262 4 6292
    carbohydrate metabolic process 2.3642E-4 8 281 4 6292
    glucan biosynthetic process 3.5318E-4 8 23 2 6292
    regulation of cell cycle 4.5761E-4 8 131 3 6292
    negative regulation of organelle organization 5.646E-4 8 29 2 6292
    negative regulation of cellular component organization 5.646E-4 8 29 2 6292
    cellular polysaccharide biosynthetic process 6.8844E-4 8 32 2 6292
    negative regulation of cell cycle process 6.8844E-4 8 32 2 6292
    polysaccharide biosynthetic process 8.2428E-4 8 35 2 6292
    regulation of carbohydrate metabolic process 8.7221E-4 8 36 2 6292
    protein complex disassembly 1.0239E-3 8 39 2 6292
    cellular protein complex disassembly 1.0239E-3 8 39 2 6292
    cellular macromolecular complex disassembly 1.0771E-3 8 40 2 6292
    macromolecular complex disassembly 1.0771E-3 8 40 2 6292
    intermediate filament-based process 1.2715E-3 8 1 1 6292
    cellular component disassembly 1.303E-3 8 44 2 6292
    regulation of organelle organization 1.8172E-3 8 52 2 6292
    cell cycle checkpoint 2.2567E-3 8 58 2 6292
    regulation of spindle organization 2.5415E-3 8 2 1 6292
    regulation of mitotic spindle organization 2.5415E-3 8 2 1 6292
    meiotic prophase I 2.5415E-3 8 2 1 6292
    histone dephosphorylation 2.5415E-3 8 2 1 6292
    meiotic cell cycle checkpoint 2.5415E-3 8 2 1 6292
    spindle stabilization 2.5415E-3 8 2 1 6292
    mitotic spindle stabilization 2.5415E-3 8 2 1 6292
    prophase 2.5415E-3 8 2 1 6292
    meiotic recombination checkpoint 2.5415E-3 8 2 1 6292
    cell cycle 2.5551E-3 8 525 4 6292
    regulation of mitotic cell cycle 3.3645E-3 8 71 2 6292
    regulation of cellular component organization 3.7475E-3 8 75 2 6292
    cellular carbohydrate biosynthetic process 4.0477E-3 8 78 2 6292
    M phase 4.7456E-3 8 294 3 6292
    carbohydrate biosynthetic process 5.474E-3 8 91 2 6292
    negative regulation of microtubule polymerization or depolymerization 6.3431E-3 8 5 1 6292
    regulation of microtubule depolymerization 6.3431E-3 8 5 1 6292
    negative regulation of microtubule depolymerization 6.3431E-3 8 5 1 6292
    cell proliferation 6.3431E-3 8 5 1 6292
    mitosis 7.1004E-3 8 104 2 6292
    nuclear division 7.3681E-3 8 106 2 6292
    microtubule depolymerization 7.6075E-3 8 6 1 6292
    organelle fission 8.3409E-3 8 113 2 6292
    negative regulation of protein complex disassembly 8.8705E-3 8 7 1 6292
    cell cycle phase 9.4607E-3 8 376 3 6292
    small molecule metabolic process 9.9017E-3 8 760 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 1 regulator activity 9.2781E-5 8 12 2 6292
    protein phosphatase regulator activity 3.5318E-4 8 23 2 6292
    phosphatase regulator activity 3.5318E-4 8 23 2 6292
    enzyme regulator activity 1.739E-3 8 207 3 6292
    glycogen (starch) synthase activity 2.5415E-3 8 2 1 6292

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