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Any process that modulates the frequency, rate or extent of microtubule depolymerization. Any process involved in maintaining the structure and integrity of the spindle. Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. The disaggregation of a protein complex into its constituent components. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups. Any process that stops, prevents or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. Any process that stops, prevents or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol. The process by which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein. Any process that stops, prevents or reduces the frequency, rate or extent of the depolymerization of astral microtubules. The removal of tubulin heterodimers from one or both ends of a microtubule. Any process that stops, prevents or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of microtubule depolymerization
Acc: GO:0007026
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
Synonyms:
  • down regulation of microtubule depolymerization
  • inhibition of microtubule depolymerization
  • microtubule rescue
  • negative regulation of microtubule catastrophe
  • negative regulation of microtubule disassembly
  • down-regulation of microtubule depolymerization
  • downregulation of microtubule depolymerization
  • microtubule stabilization
Proteins in PDR annotated with:
   This term: 70 [Search]
   Term or descendants: 91 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007026 - negative regulation of microtubule depolymerization (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle