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Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARP4
  • nucleus
  • nuclear chromatin
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • Ino80 complex
  • DNA repair
  • chromatin remodeling
  • regulation of transcription, DNA-dependent
  • histone acetylation
  • chromatin organization
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • chromatin binding
  • EAF1
  • NuA4 histone acetyltransferase complex
  • histone acetyltransferase complex
  • chromatin modification
  • DNA repair
  • molecular_function
  • EAF3
  • NuA4 histone acetyltransferase complex
  • histone acetyltransferase complex
  • DNA repair
  • histone acetylation
  • histone deacetylation
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • histone deacetylase activity
  • EAF5
  • nucleus
  • NuA4 histone acetyltransferase complex
  • DNA repair
  • molecular_function
  • EPL1
  • NuA4 histone acetyltransferase complex
  • Piccolo NuA4 histone acetyltransferase complex
  • histone acetyltransferase complex
  • DNA repair
  • histone acetylation
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • ESA1
  • NuA4 histone acetyltransferase complex
  • Piccolo NuA4 histone acetyltransferase complex
  • histone acetyltransferase complex
  • DNA repair
  • RNA elongation
  • histone acetylation
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • TRA1
  • NuA4 histone acetyltransferase complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • histone acetyltransferase complex
  • DNA repair
  • histone acetylation
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • YAF9
  • nucleus
  • NuA4 histone acetyltransferase complex
  • cytoplasm
  • Swr1 complex
  • DNA repair
  • chromatin remodeling
  • histone exchange
  • chromatin silencing at telomere
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    NuA4 histone acetyltransferase complex 4.9511E-23 8 14 8 6292
    H4/H2A histone acetyltransferase complex 4.9511E-23 8 14 8 6292
    histone acetyltransferase complex 2.9221E-18 8 44 8 6292
    nucleoplasm part 4.7294E-12 8 245 8 6292
    nucleoplasm 8.6686E-12 8 264 8 6292
    nuclear lumen 6.8142E-10 8 453 8 6292
    organelle lumen 1.4108E-8 8 660 8 6292
    intracellular organelle lumen 1.4108E-8 8 660 8 6292
    membrane-enclosed lumen 2.2645E-8 8 700 8 6292
    nuclear part 8.7333E-7 8 1103 8 6292
    protein complex 1.1143E-6 8 1137 8 6292
    Piccolo NuA4 histone acetyltransferase complex 4.2416E-6 8 3 2 6292
    macromolecular complex 2.0527E-5 8 1635 8 6292
    nucleus 1.2145E-4 8 2041 8 6292
    Swr1 complex 1.4733E-4 8 15 2 6292
    organelle part 2.9704E-4 8 2282 8 6292
    intracellular organelle part 2.9704E-4 8 2282 8 6292
    nuclear chromatin 3.5536E-3 8 73 2 6292
    chromatin 3.9464E-3 8 77 2 6292
    chromatin remodeling complex 6.4515E-3 8 99 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA repair 6.5142E-13 8 192 8 6292
    response to DNA damage stimulus 3.4901E-12 8 236 8 6292
    cellular response to stress 1.8557E-11 8 290 8 6292
    chromatin modification 6.6886E-11 8 168 7 6292
    cellular response to stimulus 1.616E-10 8 379 8 6292
    histone acetylation 2.5415E-10 8 36 5 6292
    chromatin organization 2.5589E-10 8 203 7 6292
    protein amino acid acetylation 9.204E-10 8 46 5 6292
    response to stress 1.4384E-9 8 497 8 6292
    protein amino acid acylation 3.3441E-9 8 59 5 6292
    DNA metabolic process 5.3456E-9 8 585 8 6292
    covalent chromatin modification 2.5866E-8 8 88 5 6292
    histone modification 2.5866E-8 8 88 5 6292
    response to stimulus 4.6723E-8 8 766 8 6292
    chromosome organization 2.9656E-7 8 555 7 6292
    regulation of transcription, DNA-dependent 8.2749E-7 8 358 6 6292
    regulation of RNA metabolic process 8.9854E-7 8 363 6 6292
    regulation of transcription 1.2545E-6 8 384 6 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.9869E-6 8 415 6 6292
    regulation of nitrogen compound metabolic process 2.0153E-6 8 416 6 6292
    regulation of gene expression 3.0015E-6 8 445 6 6292
    regulation of transcription from RNA polymerase II promoter 3.0646E-6 8 228 5 6292
    regulation of macromolecule biosynthetic process 3.4669E-6 8 456 6 6292
    regulation of cellular biosynthetic process 4.2489E-6 8 472 6 6292
    regulation of biosynthetic process 4.3022E-6 8 473 6 6292
    regulation of macromolecule metabolic process 5.171E-6 8 488 6 6292
    transcription, DNA-dependent 6.1796E-6 8 503 6 6292
    nucleic acid metabolic process 6.4427E-6 8 1415 8 6292
    RNA biosynthetic process 6.5498E-6 8 508 6 6292
    regulation of primary metabolic process 7.018E-6 8 514 6 6292
    regulation of cellular metabolic process 8.9774E-6 8 536 6 6292
    regulation of metabolic process 1.0114E-5 8 547 6 6292
    transcription 1.0669E-5 8 552 6 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.4527E-5 8 1566 8 6292
    transcription from RNA polymerase II promoter 2.0367E-5 8 335 5 6292
    post-translational protein modification 2.779E-5 8 357 5 6292
    cellular nitrogen compound metabolic process 3.8773E-5 8 1770 8 6292
    organelle organization 3.9333E-5 8 1127 7 6292
    nitrogen compound metabolic process 4.2618E-5 8 1791 8 6292
    regulation of cellular process 8.9921E-5 8 796 6 6292
    regulation of biological process 1.0978E-4 8 824 6 6292
    protein modification process 1.4081E-4 8 499 5 6292
    RNA metabolic process 2.5461E-4 8 954 6 6292
    macromolecule modification 2.6414E-4 8 569 5 6292
    cellular macromolecule metabolic process 3.0018E-4 8 2285 8 6292
    macromolecule metabolic process 3.7455E-4 8 2349 8 6292
    cellular component organization 3.9282E-4 8 1582 7 6292
    cellular macromolecule biosynthetic process 8.7999E-4 8 1187 6 6292
    macromolecule biosynthetic process 8.8836E-4 8 1189 6 6292
    biological regulation 9.9402E-4 8 1213 6 6292
    gene expression 1.3613E-3 8 1283 6 6292
    primary metabolic process 2.0036E-3 8 2896 8 6292
    cellular metabolic process 2.9013E-3 8 3033 8 6292
    chromatin remodeling 3.0901E-3 8 68 2 6292
    metabolic process 3.9991E-3 8 3157 8 6292
    cellular biosynthetic process 4.1159E-3 8 1567 6 6292
    biosynthetic process 4.6438E-3 8 1602 6 6292
    cellular protein metabolic process 5.103E-3 8 1074 5 6292
    protein metabolic process 6.5695E-3 8 1136 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone acetyltransferase activity 4.2033E-12 8 17 5 6292
    lysine N-acetyltransferase activity 4.2033E-12 8 17 5 6292
    N-acetyltransferase activity 1.6019E-10 8 33 5 6292
    N-acyltransferase activity 3.3811E-10 8 38 5 6292
    acetyltransferase activity 1.4204E-9 8 50 5 6292
    transferase activity, transferring acyl groups other than amino-acyl groups 3.2417E-8 8 92 5 6292
    acyltransferase activity 3.2417E-8 8 92 5 6292
    transferase activity, transferring acyl groups 6.9655E-8 8 107 5 6292
    transferase activity 1.2965E-3 8 797 5 6292
    ATP-dependent 5'-3' DNA helicase activity 8.8705E-3 8 7 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle