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The formation of nucleosomes containing the histone H3 variant CenH3 (also called CENP-A) to form centromeric chromatin; occurs outside the context of DNA replication. The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity. Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin. Any process carried out at the cellular level by which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a macromolecular complex.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: histone exchange
Acc: GO:0043486
Aspect: Biological Process
Desc: The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.
Synonyms:
  • histone displacement
  • histone chaperone
  • histone replacement
Proteins in PDR annotated with:
   This term: 40 [Search]
   Term or descendants: 54 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043486 - histone exchange (interactive image map)
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