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Protein Overview: gi|7299468, gi|2...

General Information:
Name(s) found: gi|7299468 [NCBI NR]
gi|21356615 [NCBI NR]
Description(s) found:
Found 9 descriptions.
SHOW ALL
  • gi|7299468|gb|AAF54656.1| CG14709 [Drosophila melanogaster] [NCBI NR]
  • gi|21356615|ref|NP_650086.1| CG14709 [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 1307 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    ATP-binding cassette (ABC) transporter complex [ISS]
    Biological Process: drug transmembrane transport [ISS]
    wing disc dorsal/ventral pattern formation [IGI]
    Molecular Function: ATP binding [IEA]
    ATPase activity, coupled to transmembrane movement of substances [ISS]
    organic anion transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSMKADELP ENPRERSSPL SSLMFCFALP VLFKGRKKTL EQKDLYRALK EHKSAWDEQV  60
   61 AKNETPRLGR ALTKVFGFHL FITGVFLLAQ EFLTKVTQPI CLIGVMAYFA GNDPDRSKAQ 120
  121 LWAAGLIAGS VFSVCIGHPY MLGLLHLGMK MRIALSSLIY RKALRLSRTA LGDTTVGQVV 180
  181 NLLSNDVGRF DLVLINVHYL WIAPLELIAV TYLMYLEIGI SSMFGVAIML LFLPFQSYLG 240
  241 KRTSVLRLRT ALRTDERVRM MNEIISGIQV IKMYAWEKPF GKVVEMTRFN EMLCIKQVNY 300
  301 IRGILISFAM FLSRIFTSSS LIAFVLLGNI LNAEKAFFVT AYYNILRRSV TMFFPQGISE 360
  361 FAELLVSVRR LEAFMHRPET KVRDKSKVKN ANQKAESPNG DSPKGNGIPE NLIEFSQFQA 420
  421 RWESHSLEPT LEDINLQLGR RKLVAVIGPV GAGKSSLIQA ILGELPGESG TLRINGSYSY 480
  481 AAQEPWLFTG TVRQNILFGL DWDKHRYRTV VKKCALERDF ELLPFGDKTI VGERGASLSG 540
  541 GQKARISLAR AVYRRADIYL LDDPLSAVDT HVGRHLFDQC MRGYLRSELV ILVTHQLQFL 600
  601 EQADLIVIMD KGRISAMGTY SSMKRSGLDF AQLLTAPNKD AEDLDEIDGA GGDGLDLLNV 660
  661 PSLSRRGSKN SKPSTRNNSF TSLSSMAESM AQEASLQMQE TRVEGKIGLG LYKEYLTSGS 720
  721 SWFMIFFMVF LCLATQILCS AADYFLSYWV DKNVDGQTDI NTDPQDMYYF AALNVAVVVF 780
  781 TIVRTMLFYK MAMRSSTQLH NAMYQGITRA AMYFFNTNPS GRILNRFSKD LGQLDEVLPS 840
  841 VMLDVVQLFL TLLGIIVVIC ITNPYYLILT LALAIIFYYI REFYLKTSRD VKRLEAVARS 900
  901 PIYSHLSATI TGLPTIRALG AQKELIAEFD NLQDLHSSGY YTFLATNRAF GYYLDCFCTL 960
  961 YIVIIILNYF INPPQSPGEV GLAITQAMGM TGMVQWAMRQ SAELENTMTA VERVVEYDEI1020
 1021 EPEGEFDSRE GKKPSPSWPE KGEIIAEDLC LRYFPDPQAK YVLKALNFRI RPCEKVGIVG1080
 1081 RTGAGKSSLI NALFRLSYNE GIITIDERDT ADMGLFDLRS KISIIPQEPV LFSGSMRYNL1140
 1141 DPFEEYNDAK LWDALEEVKL KPLISELPNG LQSKISEGGS NFSVGQRQLV CLARAILREN1200
 1201 RVLVMDEATA NVDPQTDALI QATIRSKFRD CTVLTIAHRL NTIMDSDRVL VMDAGHLVEF1260
 1261 GSPYELLTSS ESKIFHGMVM ETGQNTFDSL LKVAEKAHLE SMKPKSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..410] FFAS03 2.36 No description for 2hydA was found.
    2 View Details [411..690] PSI-BLAST 69.0 No description for 2cbzA was found.
    3 View Details [691..1307] PSI-BLAST 135.0 No description for 2hydA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lipid transporter activity
    		•  6.95325922226092 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  5.4467861893359 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  5.44654566127945 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  5.44654566127945 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  5.43909190876515 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  5.4304944906989 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  5.38112407181712 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  4.87869064889244 bayes_pls_golite062009
  • ATPase activity
    		•  4.60773943958528 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  4.38591214726007 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  4.32673473878039 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  4.31087891816858 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  4.31037981322306 bayes_pls_golite062009
  • hydrolase activity
    		•  4.09315408758191 bayes_pls_golite062009
  • transporter activity
    		•  3.47953169973151 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.96171085039592 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.94175800357966 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.90743799425416 bayes_pls_golite062009
  • ATP binding
    		•  2.83986218503994 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  2.79195527951815 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  2.74359323245512 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  2.55506944753783 bayes_pls_golite062009
  • ribonucleotide binding
    		•  2.55426312645972 bayes_pls_golite062009
  • purine nucleotide binding
    		•  2.51344800975739 bayes_pls_golite062009
  • nucleotide binding
    		•  2.48057252852174 bayes_pls_golite062009
  • binding
    		•  1.81483350844459 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  0.989925244519283 bayes_pls_golite062009
  • catalytic activity
    		•  0.372934161904337 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • lipid transporter activity
    		•  7.47642599298853 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  6.80339337010085 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  5.57844095962502 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  5.57813579764186 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  5.57813579764186 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  5.5689620139321 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  5.55992639965745 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  5.50005167063544 bayes_pls_golite062009
  • cation channel activity
    		•  5.46287131955314 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  5.29074477899638 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  5.1184221202951 bayes_pls_golite062009
  • potassium channel activity
    		•  5.11125652739479 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  5.10064970232011 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  4.98276715440477 bayes_pls_golite062009
  • ion channel activity
    		•  4.87468443062464 bayes_pls_golite062009
  • heme transporter activity
    		•  4.82479229680991 bayes_pls_golite062009
  • channel activity
    		•  4.74517495695421 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.74517495695421 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  4.71935767060308 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.71152823189573 bayes_pls_golite062009
  • ATPase activity
    		•  4.69795387297193 bayes_pls_golite062009
  • cadmium ion transmembrane transporter activity
    		•  4.62439240790153 bayes_pls_golite062009
  • gated channel activity
    		•  4.61941650351493 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  4.45975815173802 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  4.45923622153365 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  4.39781350157199 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  4.38133275795019 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  4.38085303582726 bayes_pls_golite062009
  • cofactor transporter activity
    		•  4.34709589308604 bayes_pls_golite062009
  • sulfonylurea receptor activity
    		•  4.29224907929661 bayes_pls_golite062009
  • bilirubin transmembrane transporter activity
    		•  4.16465937144981 bayes_pls_golite062009
  • hydrolase activity
    		•  4.12107348093071 bayes_pls_golite062009
  • transporter activity
    		•  3.71239480053329 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.35436118751376 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  3.29518173745291 bayes_pls_golite062009
  • phosphate transmembrane-transporting ATPase activity
    		•  3.20894563245332 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.16975154423199 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.13960906549884 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.13913638619234 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.1318898376276 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.08390071341252 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  3.05511942104215 bayes_pls_golite062009
  • ATP binding
    		•  3.01346604299372 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.00745742755195 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  2.97119034312001 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  2.96271391116269 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.9271291809464 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  2.91131545957759 bayes_pls_golite062009
  • branched-chain aliphatic amino acid transmembrane transporter activity
    		•  2.88795687640992 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.77610331510393 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.77610331510393 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  2.70262534541085 bayes_pls_golite062009
  • ribonucleotide binding
    		•  2.70178191749524 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  2.69529191205818 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.67957846350199 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  2.67815672695824 bayes_pls_golite062009
  • purine nucleotide binding
    		•  2.6583477492092 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.63419811368692 bayes_pls_golite062009
  • nucleotide binding
    		•  2.62374702628143 bayes_pls_golite062009
  • sterol transporter activity
    		•  2.48473697371886 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.40292717311506 bayes_pls_golite062009
  • structural molecule activity
    		•  2.36358677562726 bayes_pls_golite062009
  • canalicular bile acid transmembrane transporter activity
    		•  2.33958437214304 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  2.29486577878686 bayes_pls_golite062009
  • structural constituent of muscle
    		•  2.27871582090443 bayes_pls_golite062009
    		• 2.20174656498665 bayes_pls_golite062009
  • vitamin transporter activity
    		•  2.1653565229854 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  2.15147988861177 bayes_pls_golite062009
  • motor activity
    		•  2.11140484670646 bayes_pls_golite062009
  • L-aspartate transmembrane transporter activity
    		•  2.05274761921715 bayes_pls_golite062009
  • voltage-gated calcium channel activity
    		•  1.96314034513078 bayes_pls_golite062009
  • binding
    		•  1.84115074893083 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  1.82177108193332 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.7703386719161 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  1.76999970080179 bayes_pls_golite062009
  • protein transporter activity
    		•  1.71214667007262 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  1.59627719545436 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  1.57734504779864 bayes_pls_golite062009
  • actin binding
    		•  1.42666717383185 bayes_pls_golite062009
  • phosphonate transmembrane transporter activity
    		•  1.40269234722336 bayes_pls_golite062009
  • carbohydrate-transporting ATPase activity
    		•  1.37859980472197 bayes_pls_golite062009
  • monocarboxylic acid transmembrane transporter activity
    		•  1.37836402136387 bayes_pls_golite062009
  • peptide-transporting ATPase activity
    		•  1.37783759788533 bayes_pls_golite062009
  • microfilament motor activity
    		•  1.33993901826495 bayes_pls_golite062009
  • molybdate ion transmembrane transporter activity
    		•  1.28313088935613 bayes_pls_golite062009
  • molybdate transmembrane-transporting ATPase activity
    		•  1.28313088935613 bayes_pls_golite062009
  • carbohydrate-importing ATPase activity
    		•  1.27327946933978 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.23799860254751 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  1.21226071573355 bayes_pls_golite062009
  • peptide transporter activity
    		•  1.19353064661766 bayes_pls_golite062009
  • peptidase activity
    		•  1.12876670227791 bayes_pls_golite062009
  • sulfate transmembrane-transporting ATPase activity
    		•  1.1220946941463 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  1.10251779925246 bayes_pls_golite062009
  • signal transducer activity
    		•  0.952448314982579 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.952448314982579 bayes_pls_golite062009
    		• 0.869999622006359 bayes_pls_golite062009
  • GTPase activity
    		•  0.83849854735032 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  0.798934081014025 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.767424210804186 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.765442336337003 bayes_pls_golite062009
  • bile acid transmembrane transporter activity
    		•  0.687612064139871 bayes_pls_golite062009
  • high voltage-gated calcium channel activity
    		•  0.64930610472341 bayes_pls_golite062009
  • cholesterol transporter activity
    		•  0.644421039250979 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.503971340374059 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.46552249844591 bayes_pls_golite062009
  • actin filament binding
    		•  0.437646833557392 bayes_pls_golite062009
  • signal sequence binding
    		•  0.42240724331108 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  0.40217318916177 bayes_pls_golite062009
  • catalytic activity
    		•  0.368034275052766 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.32730260506261 bayes_pls_golite062009
  • glucoside transmembrane transporter activity
    		•  0.31429820040527 bayes_pls_golite062009
  • maltose transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • alpha-glucoside transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • disaccharide transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • oligosaccharide transmembrane transporter activity
    		•  0.304521826432814 bayes_pls_golite062009
  • oligosaccharide-transporting ATPase activity
    		•  0.304521826432814 bayes_pls_golite062009
  • maltose-transporting ATPase activity
    		•  0.304521826432814 bayes_pls_golite062009
  • receptor activity
    		•  0.277332279568238 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.243026482777117 bayes_pls_golite062009
  • neutral amino acid transmembrane transporter activity
    		•  0.227570438294493 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  0.219473333671469 bayes_pls_golite062009
  • signal recognition particle binding
    		•  0.20866768220789 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.175442402308287 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  0.147644650870465 bayes_pls_golite062009
  • DNA binding
    		•  0.111331583742205 bayes_pls_golite062009
  • sulfate transmembrane transporter activity
    		•  0.104477131120205 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.0838130766050398 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.0536898657672154 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  0.00571427458217011 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  0.00571427458217011 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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