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Protein Overview: Rab9-PA

General Information:
Name(s) found: Rab9-PA / FBpp0080747 [FlyBase]
Description(s) found:
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  • gi|7298580|gb|AAF53798.1| Rab9 [Drosophila melanogaster] [NCBI NR]
  • gi|19921534|ref|NP_609966.1| Rab9 [Drosophila melanogaster] [NCBI NR]
  • gi|17945413|gb|AAL48761.1| RE17845p [Drosophila melanogaster] [NCBI NR]
  • The gene Rab9 is referred to in FlyBase by the symbol Dmel\Rab9 (CG9994, FBgn0032782). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19432593..19435842. It has the cytological map location 37E1. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. It is reported to be involved in the biological process</span>: retrograde transport, endosome to Golgi. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG9994-PA translation from_gene[CG9994 CG9994 FBgn0032782] seq_release:3 mol_weight=28468 cds_boundaries:(2L:19,410,955..19,413,386[+]) aa_length:256 transcript_info:[CG9994-RA seq_release:3] gene_info:[gene symbol:CG9994 FBgn0032782 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VIW6) CG9994 protein (RE17845p) [DrosMelano7227.FASTAC.txt]
  • (AE003662) CG9994 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG9994-PA [Drosophila melanogaster]gi|17945413|gb|AAL48761.1| RE17845p [Drosophila melanogaster]gi|19921534|ref|NP_609966.1| CG9994-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:join(19432872..19433063,19434667..19434861,19434923..19435306); ID=FBpp0080747; name=Rab9-PA; parent=FBgn0032782,FBtr0081206; dbxref=FlyBase:FBpp0080747,FlyBase_Annotation_IDs:CG9994-PA,GB_protein:AAF53798.1,REFSEQ:NP_609966,GB_protei [fly-100309-contam.fasta]
  • CG9994-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Rab9 CG9994-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE17845p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:join(19432872..19433063,19434667..19434861,19434923..19435306); ID=FBpp0080747; name=Rab9-PA; parent=FBgn0032782,FBtr0081206; dbxref=FlyBase:FBpp0080747,FlyBase_Annotation_IDs:CG9994-PA,GB_protein:AAF53798.1,REFSEQ:NP_609966,GB_protein:AAF53798; MD5=aeb91c32e9be5d7ad96a919380656823; length=256; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(19432872..19433063,19434667..19434861,19434923..19435306); ID=FBpp0080747; name=Rab9-PA; parent=FBgn0032782,FBtr0081206; dbxref=FlyBase:FBpp0080747,FlyBase_Annotation_IDs:CG9994-PA,GB_protein:AAF53798.1,REFSEQ:NP_609966,GB_protein:AAF53798; MD5=aeb91c32e9be5d7ad96a919380656823; length=256; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • RE17845p OS=Drosophila melanogaster GN=Rab9 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:join(19432872..19433063,19434667..19434861,19434923..19435306); ID=FBpp0080747; name=Rab9-PA; parent=FBgn0032782,FBtr0081206; dbxref=FlyBase:FBpp0080747,FlyBase_Annotation_IDs:CG9994-PA,GB_protein:AAF53798.1,REFSEQ:NP_609966,GB_protein:AAF53798,FlyMine:FBpp0080747,modMine:FBpp0080747; MD5=aeb91c32e9be5d7ad96a919380656823; length=256; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:join(19432872..19433063,19434667..19434861,19434923..19435306); ID=FBpp0080747; name=Rab9-PA; parent=FBgn0032782,FBtr0081206; dbxref=FlyBase:FBpp0080747,FlyBase_Annotation_IDs:CG9994-PA,GB_protein:AAF53798.1,REFSEQ:NP_609966,GB_protein:AAF53798,FlyMine:FBpp0080747,modMine:FBpp0080747; MD5=aeb91c32e9be5d7ad96a919380656823; length=256; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(19432872..19433063,19434667..19434861,19434923..19435306); ID=FBpp0080747; name=Rab9-PA; parent=FBgn0032782,FBtr0081206; dbxref=FlyBase:FBpp0080747,FlyBase_Annotation_IDs:CG9994-PA,GB_protein:AAF53798.1,REFSEQ:NP_609966,GB_protein:AAF53798,FlyMine:FBpp0080747,modMine:FBpp0080747; MD5=aeb91c32e9be5d7ad96a919380656823; length=256; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • RE17845p OS=Drosophila melanogaster GN=Rab9 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0080747 type=protein; loc=2L:join(19432872..19433063,19434667..19434861,19434923..19435306); ID=FBpp0080747; name=Rab9-PA; parent=FBgn0032782,FBtr0081206; dbxref=FlyBase:FBpp0080747,FlyBase_Annotation_IDs:CG9994-PA,GB_protein:AAF53798.1,REFSEQ:NP_609966,GB_protein:AAF53798,FlyMine:FBpp0080747,modMine:FBpp0080747; MD5=aeb91c32e9be5d7ad96a919380656823; length=256; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:join(19432872..19433063,19434667..19434861,19434923..19435306); ID=FBpp0080747; name=Rab9-PA; parent=FBgn0032782,FBtr0081206; dbxref=FlyBase:FBpp0080747,FlyBase_Annotation_IDs:CG9994-PA,GB_protein:AAF53798.1,REFSEQ:NP_609966,GB_protein:AAF53798,UniProt/TrEMBL:Q9VIW6,FlyMine:FBpp0080747,modMine:FBpp0080747; MD5=aeb91c32e9be5d7ad96a919380656823; length=256; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 256 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: small GTPase mediated signal transduction [IEA]
    protein transport [IEA]
    retrograde transport, endosome to Golgi [TAS]
    Molecular Function: GTP binding [IEA]
    GTPase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNMRPPQKS KLLKVVILGD GGVGKSALLT RFVANRYEEN NFHTIGVEFM NKDIVVDGER  60
   61 YTLQIWDTAG QERFRALRTP FYRGSDICLL CYALDDRDSL KGLGVWRNEF LNYADVDQDK 120
  121 FPFIVVGNKN DIPAQKRQVS SDAVQQWCAE QKVACHIETS SKAATNVTDA FVLGLRQWRH 180
  181 MECVAEAELR QHGDTIDLTR PIRLVQRRIC CTGGGGGGGG VGQDADGDDA AMHSPGKKVF 240
  241 GQKRNASKAP ATNYRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..256] PSI-BLAST 43.045757 GppNHp-Bound Rab9 GTPase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTPase activity
    		•  4.52394549632777 bayes_pls_golite062009
  • hydrolase activity
    		•  3.63069754092699 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  3.57926427233638 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • actin binding
    		•  2.84620358490972 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.67957846350199 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  2.67815672695824 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.66896300219871 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.61311581579476 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.58603227794045 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.50934147358924 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  2.3505608190884 bayes_pls_golite062009
  • motor activity
    		•  2.32425703346903 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  2.29486577878686 bayes_pls_golite062009
  • microtubule motor activity
    		•  2.26003723459523 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21184938313192 bayes_pls_golite062009
  • actin filament binding
    		•  2.1683792904715 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  1.95782378818812 bayes_pls_golite062009
  • DNA binding
    		•  1.94055378599526 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  1.89320355239381 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  1.88721318481223 bayes_pls_golite062009
  • GTP binding
    		•  1.87900088157196 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.85943679361938 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.85937484083653 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.8521191028835 bayes_pls_golite062009
  • nucleotide binding
    		•  1.84603132945448 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.83584389083042 bayes_pls_golite062009
  • kinase activity
    		•  1.80889641165674 bayes_pls_golite062009
  • protein transporter activity
    		•  1.71214667007262 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.60386625568858 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  1.59627719545436 bayes_pls_golite062009
  • ATP binding
    		•  1.5859264197035 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.55520429131224 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.53158018507951 bayes_pls_golite062009
  • GDP-dissociation inhibitor binding
    		•  1.53046363842187 bayes_pls_golite062009
  • apolipoprotein receptor activity
    		•  1.52496551152043 bayes_pls_golite062009
  • syntaxin-13 binding
    		•  1.52496551152043 bayes_pls_golite062009
  • apolipoprotein A-I binding
    		•  1.52496551152043 bayes_pls_golite062009
  • apolipoprotein A-I receptor activity
    		•  1.52496551152043 bayes_pls_golite062009
  • signal recognition particle binding
    		•  1.46975774710831 bayes_pls_golite062009
  • antigen binding
    		•  1.43656260286121 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.26314334516725 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • receptor activity
    		•  1.20313362488821 bayes_pls_golite062009
  • helicase activity
    		•  1.16085745407703 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.14475274823167 bayes_pls_golite062009
  • signal transducer activity
    		•  1.13474466330485 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.13474466330485 bayes_pls_golite062009
  • protein kinase activity
    		•  1.12864835254143 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.971476020912368 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.928091843881235 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.860102064846772 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.81256037545135 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.74918137191219 bayes_pls_golite062009
  • peptidase activity
    		•  0.742461247007442 bayes_pls_golite062009
  • transcription activator activity
    		•  0.739301862805678 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.72881469450553 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.723407201613229 bayes_pls_golite062009
  • transcription factor activity
    		•  0.697256579145077 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.69117331267457 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.59513742813869 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.59513742813869 bayes_pls_golite062009
  • sterol transporter activity
    		•  0.57614280790431 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  0.56979593127581 bayes_pls_golite062009
  • beta-catenin binding
    		•  0.567325521781475 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.543089473677103 bayes_pls_golite062009
  • ribonucleoprotein binding
    		•  0.53788302029845 bayes_pls_golite062009
  • branched-chain aliphatic amino acid transmembrane transporter activity
    		•  0.442220326523999 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  0.38711726712063 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.345873656782869 bayes_pls_golite062009
  • tubulin binding
    		•  0.326239364039846 bayes_pls_golite062009
  • receptor binding
    		•  0.309955875731734 bayes_pls_golite062009
  • peptide binding
    		•  0.304703625340488 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.249173645231486 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.237098238833913 bayes_pls_golite062009
  • microtubule binding
    		•  0.225323885896927 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.222424272323909 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.22150712609541 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.20238478387743 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  0.147644650870465 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  0.135455889967401 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.12351419478929 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • structural molecule activity
    		•  0.11239762372728 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  0.11051537119918 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.0781650226500197 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0775601177068852 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  0.0436504490626262 bayes_pls_golite062009
  • RNA binding
    		•  0.0261282189186349 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle