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View Structure Prediction Details

Protein: Rab9-PA
Organism: Drosophila melanogaster
Length: 256 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rab9-PA.

Description E-value Query
Range		 Subject
Range
rab-1 - RAS-related protein status:Confirmed UniProt:Q9UAQ6 protein_id:AAC69218.1
 214.0 [0..1] [211..1]
CRE16067, FL81_1... - RP15185 WBGene00061078 locus:Cre-rab-1 status:Confirmed, null
gi|157761211 - gi|157761211|ref|XP_001672948.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae AF16]
gi|39588485, gi|... - gi|39588485|emb|CAE58008.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae], gi|187038224|em...
 214.0 [0..1] [211..1]
ARA5_ARATH - Ras-related protein ARA-5 - Arabidopsis thaliana (Mouse-ear cress)
 209.0 [0..2] [210..53]
gi|1616614 - gi|1616614|emb|CAA69701.1| small GTP-binding protein [Nicotiana plumbaginifolia]
 209.0 [0..6] [212..2]
gi|1053067 - gi|1053067|gb|AAA80680.1| small GTP-binding protein
 208.0 [0..6] [212..2]
gi|7643790 - gi|7643790|gb|AAF65510.1| small GTP-binding protein [Capsicum annuum]
 208.0 [0..6] [212..2]
gi|215765495, gi... - gi|215765495|dbj|BAG87192.1| unnamed protein product [Oryza sativa Japonica Group], gi|215697672|dbj...
gi|125524668 - gi|125524668|gb|EAY72782.1| hypothetical protein OsI_00645 [Oryza sativa Indica Group]
 207.0 [0..6] [212..2]
gi|50911379, gi|... - gi|50911379|ref|XP_467097.1| putative GTP-binding protein YPTM2 [Oryza sativa (japonica cultivar-gro...
gi|14140133 - gi|14140133|emb|CAC39050.1| putative GTP-binding protein [Oryza sativa]
 206.0 [0..6] [212..2]
gi|421942, gi|311907 - pir||S34253 GTP-binding protein, ras-related - common tobacco, gi|311907|emb|CAA51011.1| ras-related...
 206.0 [0..6] [213..2]

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Predicted Domain #1
Region A:
Residues: [1-256] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNMRPPQKS KLLKVVILGD GGVGKSALLT RFVANRYEEN NFHTIGVEFM NKDIVVDGER  60
   61 YTLQIWDTAG QERFRALRTP FYRGSDICLL CYALDDRDSL KGLGVWRNEF LNYADVDQDK 120
  121 FPFIVVGNKN DIPAQKRQVS SDAVQQWCAE QKVACHIETS SKAATNVTDA FVLGLRQWRH 180
  181 MECVAEAELR QHGDTIDLTR PIRLVQRRIC CTGGGGGGGG VGQDADGDDA AMHSPGKKVF 240
  241 GQKRNASKAP ATNYRL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.045757
Match: 1yzlA
Description: GppNHp-Bound Rab9 GTPase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
GTPase activity 4.52394549632777 bayes_pls_golite062009
hydrolase activity 3.63069754092699 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 3.57926427233638 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
actin binding 2.84620358490972 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.67957846350199 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 2.67815672695824 bayes_pls_golite062009
cytoskeletal protein binding 2.66896300219871 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 2.61311581579476 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.58603227794045 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 2.50934147358924 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
G-protein coupled receptor activity 2.3505608190884 bayes_pls_golite062009
motor activity 2.32425703346903 bayes_pls_golite062009
amine transmembrane transporter activity 2.29486577878686 bayes_pls_golite062009
microtubule motor activity 2.26003723459523 bayes_pls_golite062009
nucleic acid binding 2.21184938313192 bayes_pls_golite062009
actin filament binding 2.1683792904715 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 1.95782378818812 bayes_pls_golite062009
DNA binding 1.94055378599526 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
purine ribonucleotide binding 1.85943679361938 bayes_pls_golite062009
ribonucleotide binding 1.85937484083653 bayes_pls_golite062009
purine nucleotide binding 1.8521191028835 bayes_pls_golite062009
nucleotide binding 1.84603132945448 bayes_pls_golite062009
transcription regulator activity 1.83584389083042 bayes_pls_golite062009
kinase activity 1.80889641165674 bayes_pls_golite062009
protein transporter activity 1.71214667007262 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.60386625568858 bayes_pls_golite062009
amino acid transmembrane transporter activity 1.59627719545436 bayes_pls_golite062009
ATP binding 1.5859264197035 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
adenyl ribonucleotide binding 1.55520429131224 bayes_pls_golite062009
adenyl nucleotide binding 1.53158018507951 bayes_pls_golite062009
GDP-dissociation inhibitor binding 1.53046363842187 bayes_pls_golite062009
apolipoprotein receptor activity 1.52496551152043 bayes_pls_golite062009
syntaxin-13 binding 1.52496551152043 bayes_pls_golite062009
apolipoprotein A-I binding 1.52496551152043 bayes_pls_golite062009
apolipoprotein A-I receptor activity 1.52496551152043 bayes_pls_golite062009
signal recognition particle binding 1.46975774710831 bayes_pls_golite062009
antigen binding 1.43656260286121 bayes_pls_golite062009
transmembrane receptor activity 1.26314334516725 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
DNA-dependent ATPase activity 1.2155186842031 bayes_pls_golite062009
receptor activity 1.20313362488821 bayes_pls_golite062009
helicase activity 1.16085745407703 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.14475274823167 bayes_pls_golite062009
signal transducer activity 1.13474466330485 bayes_pls_golite062009
molecular transducer activity 1.13474466330485 bayes_pls_golite062009
protein kinase activity 1.12864835254143 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
structural constituent of ribosome 0.860102064846772 bayes_pls_golite062009
RNA helicase activity 0.81256037545135 bayes_pls_golite062009
RNA-dependent ATPase activity 0.74918137191219 bayes_pls_golite062009
peptidase activity 0.742461247007442 bayes_pls_golite062009
transcription activator activity 0.739301862805678 bayes_pls_golite062009
DNA helicase activity 0.72881469450553 bayes_pls_golite062009
microfilament motor activity 0.723407201613229 bayes_pls_golite062009
transcription factor activity 0.697256579145077 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.69117331267457 bayes_pls_golite062009
ATP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
sterol transporter activity 0.57614280790431 bayes_pls_golite062009
nucleotide kinase activity 0.56979593127581 bayes_pls_golite062009
beta-catenin binding 0.567325521781475 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.543089473677103 bayes_pls_golite062009
ribonucleoprotein binding 0.53788302029845 bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity 0.442220326523999 bayes_pls_golite062009
drug transmembrane transporter activity 0.38711726712063 bayes_pls_golite062009
protein serine/threonine kinase activity 0.345873656782869 bayes_pls_golite062009
tubulin binding 0.326239364039846 bayes_pls_golite062009
receptor binding 0.309955875731734 bayes_pls_golite062009
peptide binding 0.304703625340488 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
structure-specific DNA binding 0.249173645231486 bayes_pls_golite062009
endopeptidase activity 0.237098238833913 bayes_pls_golite062009
microtubule binding 0.225323885896927 bayes_pls_golite062009
ribonuclease activity 0.222424272323909 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.22150712609541 bayes_pls_golite062009
DNA clamp loader activity 0.20238478387743 bayes_pls_golite062009
amino acid-transporting ATPase activity 0.147644650870465 bayes_pls_golite062009
amine-transporting ATPase activity 0.135455889967401 bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity 0.12351419478929 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
structural molecule activity 0.11239762372728 bayes_pls_golite062009
protein-DNA loading ATPase activity 0.11051537119918 bayes_pls_golite062009
double-stranded DNA binding 0.0781650226500197 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0775601177068852 bayes_pls_golite062009
G-protein-coupled receptor binding 0.0436504490626262 bayes_pls_golite062009
RNA binding 0.0261282189186349 bayes_pls_golite062009
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