Protein Overview: SVL3

General Information:
Name(s) found:	SVL3 / YPL032C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74676341\|sp\|Q03088.1\|SVL3_YEAST RecName: Full=Styryl dye vacuolar localization protein 3 [NCBI NR] gi\|6325225\|ref\|NP_015293.1\| Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; Svl3p [Saccharomyces ce [NCBI NR] pir\|\|S62042 probable membrane protein YPL032c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1171425\|gb\|AAB68187.1\| Ypl032cp [Saccharomyces cerevisiae] [NCBI NR] Styryl dye vacuolar localization protein 3 OS=Saccharomyces cerevisiae GN=SVL3 PE=1 SV=1 [Swiss-Prot] SVL3 Protein of unknown function localised to cytoplasm and bud [mips] Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck [SGD] >Q03088 (Q03088) P7102.17P [4932.FASTACCERV.txt] Chr XVI from 491360-488883, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XVI from 488883-491360, reverse complement [yeastorf3.fasta] SVL3, Chr XVI from 488883-491360, reverse complement [yeast_orfs2] SVL3 SGDID:S0005953, Chr XVI from 491360-488883, reverse complement, Verified ORF [yeastflysequest.fasta] SVL3 SGDID:S0005953, Chr XVI from 491362-488885, reverse complement, Verified ORF [10112005cervSGD.fasta] Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck [Saccharomyces cerevisiae]gi\|2132970\|pir\|\|S62042 pr [nrdb_11152004_Chlamydomonas] (Q03088) P7102.17P [cerv4932.FASTAC] SVL3 SGDID:S000005953, Chr XVI from 491362-488885, reverse complement, Verified ORF, "Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periph [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Ypl032cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Styryl dye vacuolar localization protein 3 [nr-271106-contam.fasta] Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; Svl3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] SVL3 SGDID:S000005953, Chr XVI from 491362-488885, reverse complement, Verified ORF, "Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Styryl dye vacuolar localization protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SVL3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SVL3 SGDID:S000005953, Chr XVI from 491364-488887, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck" [yeast-030211-contam.fasta] SVL3 SGDID:S000005953, Chr XVI from 491364-488887, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein of unknown function; mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; relocalizes from bud neck to cytoplasm upon DNA replication stress; SVL3 has a paralog, PAM1, that arose from the whole genome duplication" [20141208_orf_trans.fasta] TR2121\|c0_g1_i1\|g.1603 ORF TR2121\|c0_g1_i1\|g.1603 TR2121\|c0_g1_i1\|m.1603 type:complete len:826 (+) TR2121\|c0_g1_i1:402-2879(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] YPL032C SGDID:S000005953, Chr XVI from 491364-488887, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_3625\|g.2592 ORF asmbl_3625\|g.2592 asmbl_3625\|m.2592 type:complete len:826 (+) asmbl_3625:409-2886(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_3626\|g.2057 ORF ID=asmbl_3626\|g.2057 ID=asmbl_3626\|m.2057 type:complete len:826 (+) ID=asmbl_3626:409-2886(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	825 amino acids
Gene Ontology:
Cellular Component:	cellular bud [IDA] cytoplasm [IDA] cellular bud neck [IDA]
Biological Process:	endocytosis [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSLRVLA IGNNPNILFY TSRFQLAKNI DLYHVNDSKS CQFEIETEYY GKDRFELENH  60
   61 FTSIEHLTEA LSSKSSEAVF DIIIMSAPSL QELSSLASKL TSIIDSNTKI FLESSGFIQL 120
  121 EPFVKLSMES PHVNVFSILT DLDIRQIGPN HFKHFPSTAK ENTIYLGESK SSTEKYSSGV 180
  181 ITLLTTFEKL FAKLFSNIKI NLCNFSSIEF LSQQWKLAIS RICFDPLLIM FEQENPSDLD 240
  241 QQIIAKPLIS GLVTEIITVA KTMGARLNSS HDNENSLLSL WKNSYHSTNK PPALVYHFIH 300
  301 QTTPLNIDIL LLQTILLADD FGIKTPYLEF LYSVLSQFER LNSGKSKWFI RSDEKTQILQ 360
  361 SLQKSQKNES ALQTQITSLQ GQISKLRQEL LMQAKQHEME TNELKEKHQV ALKAQAQAQA 420
  421 QAQSQAQTSI EALTPTEATN QSDTNEYKAT GTPNLRDIED MALYSVNYGD SPVRSPPPVV 480
  481 SSQPQMNSPL SSHSQTFGEN NGTNDKLLQE RELQLRKKEL ELQERELEFQ KRALQQQRFN 540
  541 NSNNSIPRKP SFPQLQQSAN VRSNSRGMHG TNGAMSQPAS AGNFVDPISS SIAAYDPQQP 600
  601 PSLPLQQPQQ SVQVQPFHSH SIKPTSRKNR NSNMPNIGNP SSINMSDFGR PPNNSSQTRL 660
  661 NSMPTHSIVN QNRLRSQQSK NKLNMPHATN PNNTFNQVPA PSLNNHVPTQ RQFSSSTMIE 720
  721 VTNNNNKVNN SSSNPDISTN SVVHNAMQFT NTNNNTSSTV DINDPKNIAP PPTTSVSAPS 780
  781 TPTLSSSSQM ANMASPSTDN GDNEEKNGGK KKRFGLFKKK NKSKK

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		CBF1 FYV4 MAM33 MRP1 MRP10 MRP17 MRP21 MRP4 MRP51 MRPL8 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS9 NAM9 NCL1 PET123 RIB4 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 SVL3 SWS2 YDR124W YJR096W YKL151C YSP1
View Details	Ho Y, et al. (2002)		ADR1 BMH1 BNR1 BOI2 CSR2 CYK3 GSY2 KCS1 NTH1 REG1 SOK1 STU1 SVL3 YFR017C YIL028W

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)
View Run	BOI1	Sample bob1 (2nd set) from october 2005	McCusker D, et al (2007)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CRN1	SVL3	2	Drees BL, et al. (2001)
View Screen	INP52	SVL3	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	SVL3	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..213]	PSI-BLAST	53.221849	Ketopantoate reductase PanE
2	View Details	[214..345]	PSI-BLAST	53.221849	Ketopantoate reductase PanE
3	View Details	[346..550]	PSI-BLAST	28.221849	Heavy meromyosin subfragment
4	View Details	[551..825]	MSA	11.372997	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2