Protein Overview: IES4

General Information:
Name(s) found:	IES4 / YOR189W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6324763\|ref\|NP_014832.1\| Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses; Ies4p [Saccharomyces cerevisiae] [NCBI NR] gi\|61213192\|sp\|Q08561.1\|IES4_YEAST RecName: Full=Ino eighty subunit 4 [NCBI NR] pir\|\|S67081 hypothetical protein YOR189w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1420453\|emb\|CAA99398.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Ino eighty subunit 4 OS=Saccharomyces cerevisiae GN=IES4 PE=1 SV=1 [Swiss-Prot] IES4 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions [mips] Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses [SGD] >Q08561 (Q08561) Chromosome XV reading frame ORF YOR189W [4932.FASTACCERV.txt] Chr XV from 689624-689974 [hmr_yeast5_DM3-1_pombe.fasta] Chr XV from 689623-689973 [yeastorf3.fasta] YOR189W, Chr XV from 689623-689973 [yeast_orfs2] IES4 SGDID:S0005715, Chr XV from 689624-689974, Verified ORF [yeastflysequest.fasta] Ies4p [Saccharomyces cerevisiae]gi\|1420453\|emb\|CAA99398.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|2132079\|pir\|\|S67081 hypothetical protein YOR189w - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas] (Q08561) S.cerevisiae chromosome XV reading frame ORF YOR189w [cerv4932.FASTAC] IES4 SGDID:S000005715, Chr XV from 689624-689974, Verified ORF, "Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] IES4 SGDID:S000005715, Chr XV from 689625-689975, Verified ORF, "Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions" [yeast-contam.fasta] IES4 SGDID:S000005715, Chr XV from 689625-689975, Verified ORF, "Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; Ies4p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Ino eighty subunit 4 [nr-271106-contam.fasta] [chemostatdb.fasta] Ino eighty subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IES4 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] IES4 SGDID:S000005715, Chr XV from 689624-689974, Genome Release 64-1-1, Verified ORF, "Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses" [yeast-030211-contam.fasta] IES4 SGDID:S000005715, Chr XV from 689624-689974, Genome Release 64-2-1, Verified ORF, "Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses" [20141208_orf_trans.fasta] YOR189W SGDID:S000005715, Chr XV from 689624-689974, Genome Release 64-1-1, Verified ORF, "Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	116 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MSQESSVLSE SQEQLANNPK IEDTSPPSAN SRDNSKPVLP WDYKNKAIEI KSFSGYKVNF 60 61 TGWIRRDVRE ERQRGSEFTA SDVKGSDDKA TRKKEPADED PEVKQLEKEG EDGLDS

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		ARP4 ARP5 ARP6 ARP8 CCA1 EAF1 EAF5 EAF6 EAF7 EPL1 ESA1 IES1 IES2 IES3 IES4 IES5 IES6 INO80 NHP10 NTO1 PIH1 RVB1 RVB2 SAS3 SWC3 SWC4 SWC5 SWC7 SWR1 TAH1 TRA1 VPS71 VPS72 YAF9 YNG2

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	IES4	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..116]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle