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Protein Overview: REH1

General Information:
Name(s) found: REH1 / YLR387C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Cytoplasmic 60S subunit biogenesis factor, associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturation; contains dispersed C2H2 zinc finger domains [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 432 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    [NOT]budding cell bud growth [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTFFTCNC CVIQFKTSDL QRYHMKTEWH RYNLKRRIAN LPPIGAEQFA EKLQISEKEQ  60
   61 AENQVDEFGF PVLKPVMNQS NALPQKQKKP IKSKRGRKVG TNLLKRKDRD IAKEKQNRSV 120
  121 SPSGSISSQL SNLTVGTENT NTDYGEDTVS EYGFTSDSNY EYATSDEELD IADKPSDKEN 180
  181 EKITITECIY CGKDNKEVER NVKHMFSEHG LFIPERSYLI DLNGLLEFLI KMIVIDHNCL 240
  241 CCNFHGSGLE SIRAHMASKR HCRLPYETKE ERQLFAPFYD FTYDDHSISK NLQNDRAITS 300
  301 KLSSVYGAKN DEEDGEVDIT LVSSENDINA NYTTVSIDES GLELTLPTGA RLGHRAGQRY 360
  361 YRQNLPSQPN PNESRRTITA ADRRMVSGVT EKQYKKGMKK MQQLEKNAIN TQIRREIKRV 420
  421 NFQTHYRDEL LQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CAB3 CHD1 CKA1 CKA2 CKB1 CKB2 ELF1 HOT1 MSC3 NRG1 PGA2 REH1 RIM13 VHS3 YLR407W
    View Details Qiu et al. (2008) AST2 GCN4 MON1 REH1 RPS30B, RPS30A YPL199C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen REH1 HTZ1 2 Unpublished Fields Lab Data
    View Screen REH1 SMA1 2 Unpublished Fields Lab Data
    View Screen REH1 MVP1 1 Unpublished Fields Lab Data
    View Screen REH1 YMR124W 1 Unpublished Fields Lab Data
    View Screen VPS64 REH1 1 Unpublished Fields Lab Data
    View Screen REH1 RAP1 1 Unpublished Fields Lab Data
    View Screen RAD54 REH1 1 Unpublished Fields Lab Data
    View Screen REH1 NUR1 1 Unpublished Fields Lab Data
    View Screen REH1 ABP140 1 Unpublished Fields Lab Data
    View Screen REH1 INO2 1 Unpublished Fields Lab Data
    View Screen REH1 FSF1 1 Unpublished Fields Lab Data
    View Screen REH1 MTQ2 1 Unpublished Fields Lab Data
    View Screen REH1 ATC1 1 Unpublished Fields Lab Data
    View Screen REH1 YPL141C 1 Unpublished Fields Lab Data
    View Screen REH1 BFR2 1 Unpublished Fields Lab Data
    View Screen REH1 DBF20 1 Unpublished Fields Lab Data
    View Screen REH1 TFB3 1 Unpublished Fields Lab Data
    View Screen SPO1 REH1 1 Unpublished Fields Lab Data
    View Screen REH1 RTT105 1 Unpublished Fields Lab Data
    View Screen REH1 RPL1A, RPL1B 1 Unpublished Fields Lab Data
    View Screen REH1 CDC12 1 Unpublished Fields Lab Data
    View Screen REH1 PEX28 1 Unpublished Fields Lab Data
    View Screen REH1 JIP3 1 Unpublished Fields Lab Data
    View Screen REH1 SML1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data REH1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] PSI-BLAST 27.0 Designed zinc finger protein
    2 View Details [97..289] MSA 10.533996 View MSA. No confident structure predictions are available.
    3 View Details [290..432] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.36961042761402 bayes_pls_golite062009
  • DNA binding
    		•  1.83298509797997 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.81905872620454 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.79634171647159 bayes_pls_golite062009
  • RNA binding
    		•  1.69160965456631 bayes_pls_golite062009
  • transcription factor activity
    		•  0.972881822816115 bayes_pls_golite062009
  • transcription activator activity
    		•  0.953363449552372 bayes_pls_golite062009
  • protein binding
    		•  0.852654490075478 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.246568450747506 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.095249486073484 bayes_pls_golite062009
  • chromatin binding
    		•  0.0383915131562336 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle