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Protein Overview: AST2

General Information:
Name(s) found: AST2 / YER101C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 430 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEKILENKD PKLEAMTVDH EVSAPKPIPV DEPTLTRVAR PLRHVRHIPV KSLVFHSKHG  60
   61 PITFSYENKI KLPISKNKLV VQVNYVGLNP VDMKIRNGYT KPIYGEAGIG REYSGVITHV 120
  121 GDNLTNRWNV GDDVYGIYYH PKLAIGALQS SLLIDPRVDP ILMRPKNTLS PEKAAGSLFC 180
  181 LGTALNLLAQ LKEKDQLNTE SNVLINGGTS SVGMFAIQLL KRYYKVSKKL VVVTSGNGAA 240
  241 VLSEHFPDLK DEIIFINYLS CRGKSSKPLR RMLDTGKVVD YDDFNTLKET EDYTQGKFNV 300
  301 VLDFIGGYDI LSHSSSLIHA KGAYITTVGD YVGNYKKDVF DSWDNPSANA RKMFGSMLWS 360
  361 YDYSHFYFDP NIKIIPKKND WIHECGKLLN EGVVDCVVDK VYSWKNFKEA FSYMATQRAQ 420
  421 GKLIMKVEGF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AAC3 AST2 ATG27 DUR3 ECM12 MON1 PRE2 PUF2 REH1 RPL29 RPL41A, RPL41B RPS30B, RPS30A RXT3 SFT1 SLX8 TKL2 TPS1 YDL133W YGR117C YGR149W YLR030W YLR326W YML6 YOR292C YPL199C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SEC17 AST2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data AST2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..210]
    [359..430]    		 PSI-BLAST 125.0 Alcohol dehydrogenase
    2 View Details [211..358] PSI-BLAST 125.0 Alcohol dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  4.14217990101505 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.13774251017711 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.96417104841008 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  1.68027744358887 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  1.22416351603098 bayes_pls_golite062009
  • chaperone binding
    		•  1.19079350615542 bayes_pls_golite062009
  • DNA binding
    		•  1.02274180655721 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.955628854752953 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.905392379451071 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.901776352952123 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  0.839863523675468 bayes_pls_golite062009
  • transporter activity
    		•  0.793769336118517 bayes_pls_golite062009
  • structural molecule activity
    		•  0.75267483298133 bayes_pls_golite062009
  • ligase activity
    		•  0.742884668104576 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.635891484075352 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.555188550031886 bayes_pls_golite062009
  • binding
    		•  0.553666136934364 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.51503848775098 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.410307505174239 bayes_pls_golite062009
  • transcription factor activity
    		•  0.368443846770004 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.29802814097478 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  0.261132005311306 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.239024094835991 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.212092278332619 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.113340150368917 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0696058100530442 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0591634687578807 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0560606007580392 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle