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Protein Overview: SWA2

General Information:
Name(s) found: SWA2 / YDR320C [SGD]
Description(s) found:
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  • gi|914999|gb|AAB64756.1| Ydr320cp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|74583574|sp|Q06677.1|SWA2_YEAST RecName: Full=Auxilin-like clathrin uncoating factor SWA2; AltName: Full=DnaJ-related protein SWA2; Short=J protein SWA2; AltName: Full=Synthetic lethal with ARF1 protein 2; AltName: Full=Bud site selection protein 24 [NCBI NR]
  • gi|6320526|ref|NP_010606.1| Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles; Swa2p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S59786 hypothetical protein YDR320c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Auxilin-like clathrin uncoating factor SWA2 OS=Saccharomyces cerevisiae GN=SWA2 PE=1 SV=1 [Swiss-Prot]
  • SWA2 Clathrin-binding protein required for normal clathrin function and for uncoating of clathrin-coated vesicles [mips]
  • Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles [SGD]
  • SWA2, Chr IV from 1106087-1108093, reverse complement [yeast_orfs2]
  • Chr IV from 1106087-1108093, reverse complement [yeastorf3.fasta]
  • Chr IV from 1108093-1106087, reverse complement [yeastorf5.fasta]
  • >Q06677 (Q06677) SIMILARITY to human transformation-sensitive protein IEF [4932.FASTACCERV.txt]
  • SWA2 SGDID:S0002728, Chr IV from 1108094-1106088, reverse complement, Verified ORF [yeastflysequest.fasta]
  • SWA2 SGDID:S0002728, Chr IV from 1108096-1106090, reverse complement, Verified ORF [10112005cervSGD.fasta]
  • Swa2p [Saccharomyces cerevisiae]gi|914999|gb|AAB64756.1| Ydr320cp [Saccharomyces cerevisiae]gi|2131428|pir||S59786 hypothetical protein YDR320c - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas]
  • (Q06677) Ydr320cp [cerv4932.FASTAC]
  • SWA2 SGDID:S000002728, Chr IV from 1108096-1106090, reverse complement, Verified ORF, "Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • SWA2 SGDID:S000002728, Chr IV from 1108098-1106092, reverse complement, Verified ORF, "Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles" [yeast-contam.fasta]
  • SWA2 SGDID:S000002728, Chr IV from 1108099-1106093, reverse complement, Verified ORF, "Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Ydr320cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles; Swa2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Auxilin-like clathrin uncoating factor SWA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SWA2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • SWA2 SGDID:S000002728, Chr IV from 1108101-1106095, Genome Release 64-1-1, reverse complement, Verified ORF, "Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles" [yeast-030211-contam.fasta]
  • SWA2 SGDID:S000002728, Chr IV from 1108101-1106095, Genome Release 64-2-1, reverse complement, Verified ORF, "Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles" [20141208_orf_trans.fasta]
  • YDR320C SGDID:S000002728, Chr IV from 1108101-1106095, Genome Release 64-1-1, reverse complement, Verified ORF, "Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 668 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IDALink to PubMed article]
    Biological Process: telomere maintenance [IMPLink to PubMed article]
    endoplasmic reticulum organization [IMPLink to PubMed article]
    Molecular Function: protein binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDPFAHLLT SLKNKDSASA SKETTPQSSN SPSITGSAVA DVARTDKSPN DSLHSISAPP  60
   61 LIPSPKVDFS APPLVPTNST TKSNTANNTP PSALANTDDD FNQLFGMGTV TTTDTIQKPD 120
  121 EDYYGSKEDH LYNGDDALVD EVKDMEIARL MSLGLSIEEA TEFYENDVTY ERYLEILKSK 180
  181 QKERNDLAIR KKESGIKMEK SGLSNIVGTD SNNLFSMATD FFNKGKKLVD QWTSFPPEAN 240
  241 DRLNNYSKTH DKVEDYDLPQ VNDSPNRILF EDNEVVENLP PADNPDQDLL TDFETKIDIT 300
  301 KRTAPDVSHS SSPTSGILIE ENSRRNEPLI EDSLLDFSEG NLTNSKSNED STLFNENSNT 360
  361 DSTIPISDIE LSGYNEFKAK GTSLFKNGDY INSLQEYEKS LNTLPLNHPL RIIALSNIIA 420
  421 SQLKIGEYSK SIENSSMALE LFPSSKAKWK NKISNSDPER SFNDIWPKIM IRRAESFEHL 480
  481 ESFKKALETY QELIKKNFFD DKIMQGKRRC QDFINPPPVK KSMPVKKKTT TTSPATKKQN 540
  541 LTASSSNSPI SVDSTSEIKK RELENAKLAL YDKVFEKISS WKDGKDDDIR HLLANLSSLL 600
  601 TWCNWKDVSM QDLVMPKRVK ITYMKAVAKT HPDKIPESLS LENKMIAENI FSTLSIAWDK 660
  661 FKLQNDIN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) GSG1 POL4 RPN1 RPN10 RPN11 RPN12 RPN13 RPN2 RPN5 RPN6 RPN8 RPN9 RPT1 RPT2 RPT4 RPT5 RPT6 SEM1 SLX5 SPG5 SWA2 UBP6
    View Details Krogan NJ, et al. (2006) CSI1 CSN9 ERV46 FPR2 HUL5 IQG1 MOT1 MPT5 NAS6 NMD3 NPT1 PCI8 PEP1 PST1 PUS9 RPN1 RPN10 RPN11 RPN12 RPN13 RPN14 RPN2 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 RRI1 RRI2 SEC18 SEM1 SKP1 SPG5 SPO77 SQT1 SWA2 TCB2 TIP41 TOD6 TOR2 TSR4 UBP6 YEN1 YKL027W YMR258C YNL022C YPR003C YPT52

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIF2 No Comments Cheeseman IM, et al. (2002)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)
    View Run MLP2 #16 Mitotic-New search criteria Keck JM, et al. (2011)
    View Run None Entered #18 Mitotic Prep4-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen RAD1 SWA2 2 Unpublished Fields Lab Data
    View Screen LSM12 SWA2 1 Unpublished Fields Lab Data
    View Screen SPO1 SWA2 1 Unpublished Fields Lab Data
    View Screen YPT53 SWA2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SWA2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..352] deduced N/A No confident structure predictions are available.
    2 View Details [353..543] PSI-BLAST 52.70927 Hop
    3 View Details [544..598] deduced N/A No confident structure predictions are available.
    4 View Details [599..668] PSI-BLAST 4.522879 DnaJ chaperone, N-terminal (J) domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.0541759325193 bayes_pls_golite062009
  • protein binding
    		•  1.81676109739118 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle