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Protein Overview: GSG1

General Information:
Name(s) found: GSG1 / YDR108W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Subunit of TRAPP (transport protein particle), a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment; protein has late meiotic role, following DNA replication [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 698 amino acids

    Gene Ontology:
    Cellular Component: TRAPP complex [IDALink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [IMPLink to PubMed article]
    vesicle organization [IMPLink to PubMed article]
    autophagy [IMPLink to PubMed article]
    peroxisome degradation [IMPLink to PubMed article]
    meiosis [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFSYEHYMN LLFHLDNSKE TVPPEIAKRI ISNAIAPVIT VTSTPLFDKH IQETYKVDSL  60
   61 YMLLRFFGGC VSDRDQANEA KVGQHEHEVC DASDSTDSIP KNKNLEVPNL SKKGSRSRSN 120
  121 SLFQRDSTQS QYIRFTRPLG DLIETRDAND MLFNYHSLEV FLDNYLKLVA ANTDEMVPHN 180
  181 LLKKSIYHSF FSLAISSTNN LSPYETFNHP ILSLIALDIS NGEVYEDARD LLVNFKNLNH 240
  241 NTENFPIFMN TNEMLPVFLL CYNDDSQEEF EKCQALAKKL KKQLFVESIL LALWKDSFIY 300
  301 DENSVIQLHQ PVMSSLEEIL FFLQAPTQTT LSLALINSIY DMLDYLVYDL MIPFMKRKVS 360
  361 FWEETILQPR KSLFNGAKFF KKFMNKNPVN GNHQHNSLTR DSQGNEYFAS SSSEFLMRKL 420
  421 ADWSMMLSDF KTAYSTYESL MDDLDAFPKY LASCIEWCAV SLLMGAQSIV TVKMIKNDIN 480
  481 PLIERALATY ENCSRIQRGK GKESNSLDVT EPVRSYETRC MILASELFLS LSNTWTSTPY 540
  541 AIQYLETILD ECKLGPCSQI MVWERLSDCY NLRVDPRIKH RVGAMKKDAK DTEDLRGEHK 600
  601 YSTDHFTDED ILSEGLTRRR KAAFFRLIAA KKWAEQKQWR QVSWCLKDIE STYSEIKFLH 660
  661 GNGLILSKLK NQLNLKDVDS APRPSEKNLT RTSVSFIG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BET3 BET5 GSG1 KRE11 POL4 RPN1 RPN10 RPN11 RPN12 RPN13 RPN2 RPN5 RPN6 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 SLX5 SWA2 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33 UBP6
    View Details (MIPS) Mewes HW, et al. (2004) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Krogan NJ, et al. (2006) GSG1 YPR078C
    View Details Gavin AC, et al. (2006) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Gavin AC, et al. (2002) BET3 BET5 FKS1 GSG1 KRE11 RVB2 SKN1 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Qiu et al. (2008) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GSG1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..327] deduced N/A No confident structure predictions are available.
    2 View Details [328..500] MSA 2.006956 View MSA. No confident structure predictions are available.
    3 View Details [501..698] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle