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View Structure Prediction Details

Protein: RAB35_RAT
Organism: Rattus norvegicus
Length: 201 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAB35_RAT.

Description E-value Query
Range		 Subject
Range
RAB1_DIPOM - Ras-related protein ORAB-1 OS=Diplobatis ommata PE=2 SV=1
 244.0 [0..1] [201..1]
rab-1 - RAS-related protein status:Confirmed UniProt:Q9UAQ6 protein_id:AAC69218.1
 244.0 [0..1] [201..4]
gi|37360618 - gi|37360618|dbj|BAC98287.1| mKIAA3012 protein [Mus musculus]
 244.0 [0..1] [201..52]
CRE16067, FL81_1... - RP15185 WBGene00061078 locus:Cre-rab-1 status:Confirmed, null
gi|157761211 - gi|157761211|ref|XP_001672948.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae AF16]
gi|39588485, gi|... - gi|39588485|emb|CAE58008.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae], gi|187038224|em...
 244.0 [0..1] [201..4]
gi|61365844, gi|... - gi|61365844|gb|AAX42772.1| RAB1A member RAS oncogene family [synthetic construct], gi|54695924|gb|AA...
 243.0 [0..1] [201..4]
gi|53733986 - gb|AAH83951.1| Unknown (protein for MGC:97957) [Xenopus laevis]
gi|55741705 - ref|NP_001003153.1| RAB1A, member RAS oncogene family [Canis familiaris]
gi|120419448, gi... - gi|76629653|ref|XP_869337.1| PREDICTED: similar to RAB1, member RAS oncogene family isoform 2 [Bos t...
gi|109103156 - gi|109103156|ref|XP_001090072.1| PREDICTED: similar to RAB1, member RAS oncogene family isoform 4 [M...
gi|61355917, gi|... - gi|61355926|gb|AAX41191.1| RAB1A member RAS oncogene family [synthetic construct], gi|61355917|gb|AA...
tr|G1TCS8|G1TCS8... - pep:novel chromosome:oryCun2:2:121177308:121212010:1 gene:ENSOCUG00000017003 transcript:ENSOCUT00000...
RAB1A - RAB1A, member RAS oncogene family
RAB1A_RAT - Ras-related protein Rab-1A OS=Rattus norvegicus GN=Rab1A PE=1 SV=3
RAB1A_CANLF - Ras-related protein Rab-1A OS=Canis lupus familiaris GN=RAB1A PE=1 SV=3
gi|159906367 - gi|159906367|gb|ABX10872.1| RAB1A [Capra hircus]
RAB1A_MOUSE - Ras-related protein Rab-1A OS=Mus musculus GN=Rab1A PE=1 SV=3
tr|M3VYP9|M3VYP9... - RAB1A, member RAS oncogene family OS=Felis catus GN=RAB1A PE=4 SV=1
gi|149727528 - gi|149727528|ref|XP_001493347.1| PREDICTED: similar to RAB1A, member RAS oncogene family [Equus caba...
 242.0 [0..1] [201..4]
gi|50738954 - gi|50738954|ref|XP_419342.1| PREDICTED: similar to ras-related protein [Gallus gallus]
 242.0 [0..6] [201..197]
RAB1A_PIG - Ras-related protein Rab-1A OS=Sus scrofa GN=RAB1A PE=2 SV=3
 242.0 [0..1] [201..4]

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Predicted Domain #1
Region A:
Residues: [1-201] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARDYDHLFK LLIIGDSGVG KSSLLLRFAD NTFSGSYITT IGVDFKIRTV EINGEKVKLQ  60
   61 IWDTAGQERF RTITSTYYRG THGVIVVYDV TSAESFVNVK RWLHEINQNC DDVCRILVGN 120
  121 KNDDPERKVV ETEDAYKFAG QMGIQLFETS AKENVNVEEM FNCITELVLR AKKDNLAKQQ 180
  181 QQQQNDVVKL TKNSKRKKRC C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.69897
Match: 1ukvY
Description: Structure of RabGDP-dissociation inhibitor in complex with prenylated YPT1 GTPase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
GTPase activity 4.52394549632777 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 3.57926427233638 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.4837867129694 bayes_pls_golite062009
ion transmembrane transporter activity 3.35436118751376 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
cation transmembrane transporter activity 3.08390071341252 bayes_pls_golite062009
structural constituent of ribosome 3.070470376968 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.88476360771975 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.85628130885095 bayes_pls_golite062009
actin binding 2.84620358490972 bayes_pls_golite062009
pyrophosphatase activity 2.78950165917982 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.76996223962376 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.7670079419026 bayes_pls_golite062009
hydrolase activity 2.73675310079844 bayes_pls_golite062009
cytoskeletal protein binding 2.66896300219871 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 2.61311581579476 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity 2.44176688200537 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.40292717311506 bayes_pls_golite062009
amine transmembrane transporter activity 2.29486577878686 bayes_pls_golite062009
actin filament binding 2.1683792904715 bayes_pls_golite062009
motor activity 2.1532118704195 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 2.12727614888121 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
microtubule motor activity 2.10113120386841 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
structural molecule activity 2.08211451183607 bayes_pls_golite062009
amine-transporting ATPase activity 2.06822309603506 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 1.95782378818812 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
1.86855842486607 bayes_pls_golite062009
organic acid transmembrane transporter activity 1.77111739879769 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 1.75695995185278 bayes_pls_golite062009
protein transporter activity 1.71214667007262 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.58971273330352 bayes_pls_golite062009
ribonucleotide binding 1.53142082854758 bayes_pls_golite062009
purine nucleotide binding 1.52938239070386 bayes_pls_golite062009
purine ribonucleotide binding 1.52887308780164 bayes_pls_golite062009
nucleotide binding 1.52746968836881 bayes_pls_golite062009
cation channel activity 1.33585529285301 bayes_pls_golite062009
transmembrane receptor activity 1.26314334516725 bayes_pls_golite062009
ATP binding 1.23942044024113 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.23799860254751 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
DNA-dependent ATPase activity 1.2155186842031 bayes_pls_golite062009
adenyl ribonucleotide binding 1.21044170258803 bayes_pls_golite062009
receptor activity 1.20313362488821 bayes_pls_golite062009
adenyl nucleotide binding 1.19481945569892 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
signal transducer activity 1.13474466330485 bayes_pls_golite062009
molecular transducer activity 1.13474466330485 bayes_pls_golite062009
kinase activity 1.11120928120082 bayes_pls_golite062009
voltage-gated cation channel activity 1.00384984515681 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
peptide-transporting ATPase activity 0.911425383309011 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.908046791062776 bayes_pls_golite062009
transcription activator activity 0.889929694023098 bayes_pls_golite062009
voltage-gated ion channel activity 0.889208591820696 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
protein methyltransferase activity 0.876296121718575 bayes_pls_golite062009
antigen binding 0.873255527583104 bayes_pls_golite062009
voltage-gated channel activity 0.871525745291603 bayes_pls_golite062009
ion channel activity 0.848261056209476 bayes_pls_golite062009
channel activity 0.806331380134838 bayes_pls_golite062009
passive transmembrane transporter activity 0.806331380134838 bayes_pls_golite062009
substrate-specific channel activity 0.799997700906738 bayes_pls_golite062009
DNA polymerase activity 0.795745617990735 bayes_pls_golite062009
structure-specific DNA binding 0.782430219754236 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.771854032852428 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.767424210804186 bayes_pls_golite062009
peptide transporter activity 0.73541731084591 bayes_pls_golite062009
DNA helicase activity 0.72881469450553 bayes_pls_golite062009
microfilament motor activity 0.723407201613229 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 0.69784475011795 bayes_pls_golite062009
potassium channel activity 0.694411056320469 bayes_pls_golite062009
G-protein coupled receptor activity 0.682467561649336 bayes_pls_golite062009
gated channel activity 0.650050847753837 bayes_pls_golite062009
steroid hormone receptor binding 0.647625526012423 bayes_pls_golite062009
calcium channel activity 0.636216614902039 bayes_pls_golite062009
histone methyltransferase activity 0.63002958837536 bayes_pls_golite062009
double-stranded DNA binding 0.6071273686445 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.5886142102548 bayes_pls_golite062009
amino acid transmembrane transporter activity 0.585668369219566 bayes_pls_golite062009
beta-catenin binding 0.567325521781475 bayes_pls_golite062009
sequence-specific DNA binding 0.543891899378373 bayes_pls_golite062009
DNA strand annealing activity 0.495691434532349 bayes_pls_golite062009
protein transmembrane transporter activity 0.46552249844591 bayes_pls_golite062009
anion transmembrane transporter activity 0.43332053110728 bayes_pls_golite062009
signal sequence binding 0.42240724331108 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.421921195209539 bayes_pls_golite062009
drug transmembrane transporter activity 0.38711726712063 bayes_pls_golite062009
hormone receptor binding 0.351501100511918 bayes_pls_golite062009
protein kinase activity 0.351308564667977 bayes_pls_golite062009
tubulin binding 0.326239364039846 bayes_pls_golite062009
receptor binding 0.309955875731734 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
voltage-gated calcium channel activity 0.25979628626254 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 0.248918847596573 bayes_pls_golite062009
nuclear hormone receptor binding 0.246160342138071 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.243902356228423 bayes_pls_golite062009
microtubule binding 0.225323885896927 bayes_pls_golite062009
signal recognition particle binding 0.20866768220789 bayes_pls_golite062009
RNA helicase activity 0.18426050934025 bayes_pls_golite062009
RNA-dependent ATPase activity 0.14606996093053 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.13050483816765 bayes_pls_golite062009
protein-DNA loading ATPase activity 0.11051537119918 bayes_pls_golite062009
RNA binding 0.0693163519626152 bayes_pls_golite062009
cation-transporting ATPase activity 0.0536898657672154 bayes_pls_golite062009
G-protein-coupled receptor binding 0.0436504490626262 bayes_pls_golite062009
DNA clamp loader activity 0.0111434293585004 bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0.00571427458217011 bayes_pls_golite062009
macromolecule transmembrane transporter activity 0.00571427458217011 bayes_pls_golite062009
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