From Publication: | Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3. |
Notes: | This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Apm1. The topolgies of protein complexes in this experiment are unknown. |
Complex Size: | 15 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nucleolus | 1.9043E-10 | 15 | 211 | 9 | 6292 |
nuclear lumen | 1.6291E-7 | 15 | 453 | 9 | 6292 |
clathrin coat of trans-Golgi network vesicle | 2.1836E-7 | 15 | 6 | 3 | 6292 |
AP-1 adaptor complex | 2.1836E-7 | 15 | 6 | 3 | 6292 |
organelle lumen | 2.7815E-7 | 15 | 660 | 10 | 6292 |
intracellular organelle lumen | 2.7815E-7 | 15 | 660 | 10 | 6292 |
trans-Golgi network transport vesicle membrane | 3.8158E-7 | 15 | 7 | 3 | 6292 |
membrane-enclosed lumen | 4.8715E-7 | 15 | 700 | 10 | 6292 |
clathrin adaptor complex | 1.3027E-6 | 15 | 10 | 3 | 6292 |
trans-Golgi network transport vesicle | 1.7886E-6 | 15 | 11 | 3 | 6292 |
clathrin vesicle coat | 3.9288E-6 | 15 | 14 | 3 | 6292 |
clathrin coat | 3.9288E-6 | 15 | 14 | 3 | 6292 |
AP-type membrane coat adaptor complex | 3.9288E-6 | 15 | 14 | 3 | 6292 |
clathrin coated vesicle membrane | 4.904E-6 | 15 | 15 | 3 | 6292 |
transport vesicle membrane | 4.904E-6 | 15 | 15 | 3 | 6292 |
Golgi-associated vesicle membrane | 6.027E-6 | 15 | 16 | 3 | 6292 |
non-membrane-bounded organelle | 9.3448E-6 | 15 | 959 | 10 | 6292 |
intracellular non-membrane-bounded organelle | 9.3448E-6 | 15 | 959 | 10 | 6292 |
endomembrane system | 1.5875E-5 | 15 | 398 | 7 | 6292 |
nuclear outer membrane | 3.9595E-5 | 15 | 86 | 4 | 6292 |
clathrin-coated vesicle | 4.7349E-5 | 15 | 31 | 3 | 6292 |
vesicle coat | 6.2763E-5 | 15 | 34 | 3 | 6292 |
nuclear membrane | 6.3611E-5 | 15 | 97 | 4 | 6292 |
coated vesicle membrane | 6.8549E-5 | 15 | 35 | 3 | 6292 |
cytoplasmic vesicle membrane | 6.8549E-5 | 15 | 35 | 3 | 6292 |
vesicle membrane | 6.8549E-5 | 15 | 35 | 3 | 6292 |
intracellular organelle part | 8.5313E-5 | 15 | 2282 | 13 | 6292 |
organelle part | 8.5313E-5 | 15 | 2282 | 13 | 6292 |
membrane coat | 8.7975E-5 | 15 | 38 | 3 | 6292 |
coated membrane | 8.7975E-5 | 15 | 38 | 3 | 6292 |
cytoplasmic vesicle part | 9.517E-5 | 15 | 39 | 3 | 6292 |
Golgi-associated vesicle | 1.0274E-4 | 15 | 40 | 3 | 6292 |
transport vesicle | 1.465E-4 | 15 | 45 | 3 | 6292 |
Golgi membrane | 1.8913E-4 | 15 | 49 | 3 | 6292 |
nuclear part | 2.753E-4 | 15 | 1103 | 9 | 6292 |
membrane part | 4.1715E-4 | 15 | 662 | 7 | 6292 |
membrane-bounded organelle | 4.5726E-4 | 15 | 3771 | 15 | 6292 |
intracellular membrane-bounded organelle | 4.5726E-4 | 15 | 3771 | 15 | 6292 |
organelle membrane | 5.4933E-4 | 15 | 692 | 7 | 6292 |
outer membrane | 6.6197E-4 | 15 | 178 | 4 | 6292 |
organelle outer membrane | 6.6197E-4 | 15 | 178 | 4 | 6292 |
coated vesicle | 8.9828E-4 | 15 | 83 | 3 | 6292 |
nuclear envelope | 1.0074E-3 | 15 | 199 | 4 | 6292 |
nucleus | 1.3856E-3 | 15 | 2041 | 11 | 6292 |
intracellular organelle | 1.4392E-3 | 15 | 4070 | 15 | 6292 |
organelle | 1.4445E-3 | 15 | 4071 | 15 | 6292 |
nuclear membrane-endoplasmic reticulum network | 1.7834E-3 | 15 | 232 | 4 | 6292 |
membrane-bounded vesicle | 1.8748E-3 | 15 | 107 | 3 | 6292 |
cytoplasmic vesicle | 1.8748E-3 | 15 | 107 | 3 | 6292 |
cytoplasmic membrane-bounded vesicle | 1.8748E-3 | 15 | 107 | 3 | 6292 |
vesicle | 2.0297E-3 | 15 | 110 | 3 | 6292 |
Golgi apparatus part | 2.5421E-3 | 15 | 119 | 3 | 6292 |
Golgi apparatus | 7.0542E-3 | 15 | 171 | 3 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
ribosome biogenesis | 1.5492E-8 | 15 | 346 | 9 | 6292 |
ribonucleoprotein complex biogenesis | 3.0671E-8 | 15 | 374 | 9 | 6292 |
cellular component biogenesis | 6.2228E-6 | 15 | 694 | 9 | 6292 |
ribosomal large subunit biogenesis | 1.3003E-5 | 15 | 65 | 4 | 6292 |
Golgi to vacuole transport | 2.1535E-5 | 15 | 24 | 3 | 6292 |
post-Golgi vesicle-mediated transport | 5.0063E-4 | 15 | 68 | 3 | 6292 |
establishment of ribosome localization | 1.6681E-3 | 15 | 26 | 2 | 6292 |
ribosome localization | 1.6681E-3 | 15 | 26 | 2 | 6292 |
ribosomal subunit export from nucleus | 1.6681E-3 | 15 | 26 | 2 | 6292 |
vacuolar transport | 2.3055E-3 | 15 | 115 | 3 | 6292 |
rRNA processing | 3.1286E-3 | 15 | 128 | 3 | 6292 |
rRNA metabolic process | 3.7927E-3 | 15 | 137 | 3 | 6292 |
cellular process | 5.0732E-3 | 15 | 4426 | 15 | 6292 |
Golgi vesicle transport | 6.7162E-3 | 15 | 168 | 3 | 6292 |
establishment of organelle localization | 7.324E-3 | 15 | 55 | 2 | 6292 |
intracellular transport | 7.3438E-3 | 15 | 553 | 5 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
clathrin binding | 1.7886E-6 | 15 | 11 | 3 | 6292 |
binding | 1.4204E-4 | 15 | 1294 | 10 | 6292 |
ribosomal large subunit binding | 2.384E-3 | 15 | 1 | 1 | 6292 |
RNA-3'-phosphate cyclase activity | 2.384E-3 | 15 | 1 | 1 | 6292 |
nicotinamide-nucleotide adenylyltransferase activity | 2.384E-3 | 15 | 1 | 1 | 6292 |
cyclase activity | 4.7627E-3 | 15 | 2 | 1 | 6292 |
5S rRNA binding | 4.7627E-3 | 15 | 2 | 1 | 6292 |
ligase activity, forming phosphoric ester bonds | 9.5041E-3 | 15 | 4 | 1 | 6292 |