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Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H2O. Catalysis of a ring closure reaction. Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol). Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate. Catalysis of the reaction: farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate. Catalysis of the conversion of geranyl diphosphate (GPP) into the cyclic monoterpene sabinene. Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate. Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. Catalysis of the reaction: farnesyl diphosphate = alpha-humulene + diphosphate. Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A. Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate. Catalysis of the reaction: squalene = triterpene. null Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate. Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate. Catalysis of the reaction: geranyl diphosphate = (+)-bornyl diphosphate. Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively. Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene). Catalysis of the reaction: (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate. Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate. Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O. Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate. Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. null

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: cyclase activity
Acc: GO:0009975
Aspect: Molecular Function
Desc: Catalysis of a ring closure reaction.
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 187 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0009975 - cyclase activity (interactive image map)

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