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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ydr247w. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
MER1
  • nucleus
  • positive regulation of nuclear mRNA splicing, via spliceosome
  • meiosis
  • RNA binding
  • mRNA binding
  • NUM1
  • cellular bud tip
  • cell cortex
  • mitochondrion
  • mitochondrion inheritance
  • nuclear migration along microtubule
  • microtubule cytoskeleton organization
  • mitochondrial fission
  • tubulin binding
  • PAA1
  • cytoplasm
  • chromatin organization
  • diamine N-acetyltransferase activity
  • aralkylamine N-acetyltransferase activity
  • PTC4
  • cytoplasm
  • biological_process
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • catalytic activity
  • hydrolase activity
  • SEF1
  • cellular_component
  • biological_process
  • molecular_function
  • SKT5
  • cellular bud neck septin ring
  • incipient cellular bud site
  • cellular bud neck
  • response to osmotic stress
  • cytokinesis
  • cell wall chitin biosynthetic process
  • enzyme activator activity
  • SPT16
  • FACT complex
  • nuclear chromatin
  • alpha DNA polymerase:primase complex
  • transcription elongation factor complex
  • transcription initiation from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
  • transcription elongation regulator activity
  • RNA polymerase II transcription elongation factor activity
  • SYF1
  • spliceosomal complex
  • cell cycle
  • nuclear mRNA splicing, via spliceosome
  • molecular_function
  • TPS1
  • cytoplasm
  • alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)
  • carbohydrate metabolic process
  • response to drug
  • trehalose biosynthetic process
  • response to stress
  • alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
  • VHS1
  • cytoplasm
  • G1/S transition of mitotic cell cycle
  • protein amino acid phosphorylation
  • protein kinase activity
  • protein serine/threonine kinase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    FACT complex 3.1764E-3 10 2 1 6292
    alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) 6.3436E-3 10 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    positive regulation of mRNA processing 1.5893E-3 10 1 1 6292
    positive regulation of RNA splicing 1.5893E-3 10 1 1 6292
    positive regulation of nuclear mRNA splicing, via spliceosome 1.5893E-3 10 1 1 6292
    regulation of mRNA processing 3.1764E-3 10 2 1 6292
    regulation of RNA splicing 3.1764E-3 10 2 1 6292
    regulation of nuclear mRNA splicing, via spliceosome 3.1764E-3 10 2 1 6292
    cellular carbohydrate biosynthetic process 6.4015E-3 10 78 2 6292
    carbohydrate biosynthetic process 8.6334E-3 10 91 2 6292
    trehalose biosynthetic process 9.5019E-3 10 6 1 6292
    glycoside biosynthetic process 9.5019E-3 10 6 1 6292
    disaccharide biosynthetic process 9.5019E-3 10 6 1 6292
    mitochondrial fission 9.5019E-3 10 6 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    diamine N-acetyltransferase activity 1.5893E-3 10 1 1 6292
    aralkylamine N-acetyltransferase activity 1.5893E-3 10 1 1 6292
    alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 4.7611E-3 10 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle