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Protein Overview: MER1

General Information:
Name(s) found: MER1 / YNL210W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Protein with RNA-binding motifs required for meiosis-specific mRNA splicing; required for chromosome pairing and meiotic recombination [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 270 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: positive regulation of nuclear mRNA splicing, via spliceosome [TASLink to PubMed article]
    meiosis [TASLink to PubMed article]
    Molecular Function: RNA binding [IEA]
    mRNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNQHSPQPF CLDTKLVKLL EELQEGKQFN NKNIFPEKAL YLKLALDYSF FRKNLLEFCV  60
   61 HLDKIKGVIR PNYDTIYILC LLEVDLLNLV FTDNILEICL PRFVSREDLR VFNNTFYTYH 120
  121 DNRLRILQED FSQLFKKIKT KASVLCFTVE EIFLTNQEIL PQNSTVAELQ KSTNKVQTNG 180
  181 PQRHDFIVTL EIKLNKTQIT FLIGAKGTRI ESLREKSGAS IKIIPISDKM TAHERNHPES 240
  241 VQQTILISGD LYSIALAVTS IESALITLDL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) MER1 MKT1 NUM1 PAA1 POR1 PTC4 RHO2 SEF1 SKT5 SPT16 SYF1 TPS1 VHS1 VPS21

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..180] deduced N/A No confident structure predictions are available.
    2 View Details [181..270] Pfam 7.356547 KH domain No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle