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Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism. Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism. Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs. The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide. Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of nuclear mRNA splicing, via spliceosome
Acc: GO:0048024
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
Synonyms:
  • GO:0035055
  • regulation of pre-mRNA splicing
  • regulation of nuclear mRNA splicing via U2-type spliceosome
Proteins in PDR annotated with:
   This term: 16 [Search]
   Term or descendants: 138 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048024 - regulation of nuclear mRNA splicing, via spliceosome (interactive image map)
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Created and Maintained by: Michael Riffle