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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 450
Complex Size: 6 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
GAC1
  • protein phosphatase type 1 complex
  • negative regulation of transcription from RNA polymerase II promoter
  • mitotic cell cycle spindle assembly checkpoint
  • response to heat
  • glycogen metabolic process
  • meiosis
  • heat shock protein binding
  • structural molecule activity
  • protein phosphatase type 1 regulator activity
  • GIP2
  • protein phosphatase type 1 complex
  • glycogen metabolic process
  • protein amino acid dephosphorylation
  • protein phosphatase regulator activity
  • GLC7
  • protein phosphatase type 1 complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • cellular bud neck
  • spindle pole body
  • nuclear outer membrane
  • nucleolus
  • mating projection base
  • mitotic cell cycle spindle assembly checkpoint
  • cell morphogenesis during vegetative growth
  • protein amino acid dephosphorylation
  • chromosome segregation
  • cell budding
  • cellular ion homeostasis
  • meiosis
  • regulation of carbohydrate metabolic process
  • ascospore formation
  • response to heat
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • glycogen metabolic process
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone dephosphorylation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • RNA binding
  • metal ion binding
  • hydrolase activity
  • GLC8
  • nucleus
  • cytoplasm
  • glycogen biosynthetic process
  • chromosome segregation
  • enzyme activator activity
  • REG1
  • protein phosphatase type 1 complex
  • cytoplasm
  • negative regulation of transcription from RNA polymerase II promoter
  • regulation of carbohydrate metabolic process
  • glycogen metabolic process
  • vacuolar protein catabolic process
  • protein phosphatase type 1 regulator activity
  • SDS22
  • nucleus
  • cytoplasm
  • protein targeting
  • chromosome segregation
  • protein phosphatase type 1 regulator activity
  • enzyme regulator activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 1 complex 8.0408E-12 6 7 4 6292
    protein serine/threonine phosphatase complex 5.4538E-10 6 17 4 6292
    mating projection base 6.6592E-3 6 7 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    glycogen metabolic process 1.4673E-11 6 32 5 6292
    energy reserve metabolic process 1.4673E-11 6 32 5 6292
    cellular glucan metabolic process 7.0038E-11 6 43 5 6292
    glucan metabolic process 7.0038E-11 6 43 5 6292
    cellular polysaccharide metabolic process 2.5271E-10 6 55 5 6292
    polysaccharide metabolic process 3.9647E-10 6 60 5 6292
    glucose metabolic process 8.4256E-9 6 109 5 6292
    hexose metabolic process 1.6205E-8 6 124 5 6292
    monosaccharide metabolic process 2.4916E-8 6 135 5 6292
    energy derivation by oxidation of organic compounds 4.1022E-8 6 149 5 6292
    generation of precursor metabolites and energy 1.5906E-7 6 195 5 6292
    alcohol metabolic process 2.9146E-7 6 220 5 6292
    cellular carbohydrate metabolic process 6.9933E-7 6 262 5 6292
    carbohydrate metabolic process 9.9244E-7 6 281 5 6292
    small molecule metabolic process 1.3723E-4 6 760 5 6292
    chromosome segregation 1.5729E-4 6 128 3 6292
    negative regulation of nuclear division 1.5788E-4 6 21 2 6292
    negative regulation of mitotic metaphase/anaphase transition 1.5788E-4 6 21 2 6292
    mitotic cell cycle spindle assembly checkpoint 1.5788E-4 6 21 2 6292
    negative regulation of mitosis 1.5788E-4 6 21 2 6292
    spindle assembly checkpoint 1.5788E-4 6 21 2 6292
    negative regulation of cell cycle 1.736E-4 6 22 2 6292
    response to heat 2.0724E-4 6 24 2 6292
    spindle checkpoint 2.2516E-4 6 25 2 6292
    regulation of mitotic metaphase/anaphase transition 2.2516E-4 6 25 2 6292
    mitotic cell cycle spindle checkpoint 2.2516E-4 6 25 2 6292
    mitotic cell cycle checkpoint 2.8334E-4 6 28 2 6292
    protein amino acid dephosphorylation 2.8334E-4 6 28 2 6292
    regulation of nuclear division 3.042E-4 6 29 2 6292
    negative regulation of organelle organization 3.042E-4 6 29 2 6292
    negative regulation of cellular component organization 3.042E-4 6 29 2 6292
    regulation of mitosis 3.042E-4 6 29 2 6292
    response to temperature stimulus 3.4811E-4 6 31 2 6292
    negative regulation of cell cycle process 3.7116E-4 6 32 2 6292
    regulation of carbohydrate metabolic process 4.7064E-4 6 36 2 6292
    mitotic metaphase/anaphase transition 4.9732E-4 6 37 2 6292
    dephosphorylation 5.817E-4 6 40 2 6292
    regulation of organelle organization 9.8386E-4 6 52 2 6292
    negative regulation of cellular process 1.1339E-3 6 250 3 6292
    negative regulation of biological process 1.1741E-3 6 253 3 6292
    cell cycle checkpoint 1.2234E-3 6 58 2 6292
    negative regulation of transcription from RNA polymerase II promoter 1.3088E-3 6 60 2 6292
    regulation of mitotic cell cycle 1.829E-3 6 71 2 6292
    histone dephosphorylation 1.9064E-3 6 2 1 6292
    regulation of cellular component organization 2.0389E-3 6 75 2 6292
    regulation of cell cycle process 2.3745E-3 6 81 2 6292
    transcription from RNA polymerase II promoter 2.6522E-3 6 335 3 6292
    mitosis 3.8869E-3 6 104 2 6292
    nuclear division 4.0352E-3 6 106 2 6292
    organelle fission 4.5747E-3 6 113 2 6292
    response to abiotic stimulus 4.8974E-3 6 117 2 6292
    M phase of mitotic cell cycle 5.8384E-3 6 128 2 6292
    regulation of cell cycle 6.1086E-3 6 131 2 6292
    transcription, DNA-dependent 8.4571E-3 6 503 3 6292
    termination of RNA polymerase II transcription, poly(A)-independent 8.5551E-3 6 9 1 6292
    cell morphogenesis during vegetative growth 8.5551E-3 6 9 1 6292
    negative regulation of transcription, DNA-dependent 8.688E-3 6 157 2 6292
    RNA biosynthetic process 8.6959E-3 6 508 3 6292
    negative regulation of RNA metabolic process 8.7956E-3 6 158 2 6292
    regulation of primary metabolic process 8.9879E-3 6 514 3 6292
    meiosis 9.0126E-3 6 160 2 6292
    M phase of meiotic cell cycle 9.0126E-3 6 160 2 6292
    negative regulation of transcription 9.4541E-3 6 164 2 6292
    meiotic cell cycle 9.4541E-3 6 164 2 6292
    negative regulation of gene expression 9.4541E-3 6 164 2 6292
    termination of RNA polymerase II transcription, poly(A)-coupled 9.5019E-3 6 10 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphatase regulator activity 2.026E-9 6 23 4 6292
    protein phosphatase regulator activity 2.026E-9 6 23 4 6292
    protein phosphatase type 1 regulator activity 1.0569E-7 6 12 3 6292
    enzyme regulator activity 2.147E-7 6 207 5 6292
    heat shock protein binding 2.8585E-3 6 3 1 6292

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