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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
HAT2
  • nucleus
  • cytoplasm
  • histone acetyltransferase complex
    		•
  • chromatin assembly or disassembly
  • histone acetylation
  • chromatin silencing at telomere
    		•
  • histone binding
    		•
    POB3
  • nucleus
  • FACT complex
  • nuclear chromatin
  • alpha DNA polymerase:primase complex
    		•
  • chromatin remodeling
  • DNA-dependent DNA replication
  • chromatin assembly or disassembly
  • transcription initiation from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
    		•
  • chromatin binding
    		•
    RTT106
  • nucleus
    		•
  • negative regulation of transposition, DNA-mediated
  • chromatin silencing at silent mating-type cassette
  • chromatin silencing at telomere
    		•
  • histone binding
    		•
    YKU70
  • nuclear envelope
  • nuclear chromatin
  • nuclear telomeric heterochromatin
    		•
  • double-strand break repair via break-induced replication
  • double-strand break repair via homologous recombination
  • telomere maintenance
  • chromatin assembly or disassembly
  • chromatin silencing
  • double-strand break repair via nonhomologous end joining
    		•
  • RNA binding
  • damaged DNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear chromatin 7.8477E-4 4 73 2 6292
    chromatin 8.7301E-4 4 77 2 6292
    FACT complex 1.2712E-3 4 2 1 6292
    nuclear heterochromatin 4.4437E-3 4 7 1 6292
    heterochromatin 4.4437E-3 4 7 1 6292
    nuclear telomeric heterochromatin 4.4437E-3 4 7 1 6292
    telomeric heterochromatin 4.4437E-3 4 7 1 6292
    alpha DNA polymerase:primase complex 4.4437E-3 4 7 1 6292
    nuclear chromosome part 5.2287E-3 4 190 2 6292
    nuclear chromosome 7.4744E-3 4 228 2 6292
    chromosomal part 8.0617E-3 4 237 2 6292
    nucleoplasm part 8.6014E-3 4 245 2 6292
    nucleoplasm 9.9491E-3 4 264 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    chromatin assembly or disassembly 6.2849E-7 4 35 3 6292
    negative regulation of gene expression, epigenetic 1.5407E-5 4 100 3 6292
    gene silencing 1.5407E-5 4 100 3 6292
    regulation of gene expression, epigenetic 1.5407E-5 4 100 3 6292
    chromatin silencing 1.5407E-5 4 100 3 6292
    transcription, DNA-dependent 4.0396E-5 4 503 4 6292
    RNA biosynthetic process 4.2031E-5 4 508 4 6292
    transcription 5.8652E-5 4 552 4 6292
    negative regulation of transcription, DNA-dependent 5.987E-5 4 157 3 6292
    negative regulation of RNA metabolic process 6.1021E-5 4 158 3 6292
    negative regulation of transcription 6.8238E-5 4 164 3 6292
    negative regulation of gene expression 6.8238E-5 4 164 3 6292
    negative regulation of macromolecule biosynthetic process 8.2896E-5 4 175 3 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.0195E-5 4 180 3 6292
    negative regulation of nitrogen compound metabolic process 9.0195E-5 4 180 3 6292
    negative regulation of biosynthetic process 1.0438E-4 4 189 3 6292
    negative regulation of cellular biosynthetic process 1.0438E-4 4 189 3 6292
    negative regulation of macromolecule metabolic process 1.0942E-4 4 192 3 6292
    chromatin organization 1.2926E-4 4 203 3 6292
    negative regulation of cellular metabolic process 1.4102E-4 4 209 3 6292
    negative regulation of metabolic process 1.4305E-4 4 210 3 6292
    negative regulation of cellular process 2.4072E-4 4 250 3 6292
    negative regulation of biological process 2.4943E-4 4 253 3 6292
    chromatin silencing at telomere 4.4515E-4 4 55 2 6292
    RNA metabolic process 5.2568E-4 4 954 4 6292
    regulation of transcription, DNA-dependent 7.0003E-4 4 358 3 6292
    regulation of RNA metabolic process 7.294E-4 4 363 3 6292
    regulation of transcription 8.6159E-4 4 384 3 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.084E-3 4 415 3 6292
    regulation of nitrogen compound metabolic process 1.0917E-3 4 416 3 6292
    cellular macromolecule biosynthetic process 1.2614E-3 4 1187 4 6292
    macromolecule biosynthetic process 1.27E-3 4 1189 4 6292
    regulation of gene expression 1.3321E-3 4 445 3 6292
    regulation of macromolecule biosynthetic process 1.4316E-3 4 456 3 6292
    regulation of cellular biosynthetic process 1.5848E-3 4 472 3 6292
    regulation of biosynthetic process 1.5947E-3 4 473 3 6292
    gene expression 1.7224E-3 4 1283 4 6292
    regulation of macromolecule metabolic process 1.7483E-3 4 488 3 6292
    DNA recombination 1.9066E-3 4 114 2 6292
    regulation of primary metabolic process 2.0368E-3 4 514 3 6292
    regulation of cellular metabolic process 2.3038E-3 4 536 3 6292
    regulation of metabolic process 2.4454E-3 4 547 3 6292
    nucleic acid metabolic process 2.5494E-3 4 1415 4 6292
    chromosome organization 2.5518E-3 4 555 3 6292
    DNA metabolic process 2.9778E-3 4 585 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.8261E-3 4 1566 4 6292
    cellular biosynthetic process 3.8359E-3 4 1567 4 6292
    chromatin modification 4.1046E-3 4 168 2 6292
    biosynthetic process 4.1907E-3 4 1602 4 6292
    regulation of transposition, DNA-mediated 5.0773E-3 4 8 1 6292
    negative regulation of transposition, DNA-mediated 5.0773E-3 4 8 1 6292
    transposition, DNA-mediated 5.0773E-3 4 8 1 6292
    double-strand break repair via break-induced replication 5.7106E-3 4 9 1 6292
    negative regulation of transposition 5.7106E-3 4 9 1 6292
    regulation of transposition 5.7106E-3 4 9 1 6292
    cellular nitrogen compound metabolic process 6.2471E-3 4 1770 4 6292
    nitrogen compound metabolic process 6.5492E-3 4 1791 4 6292
    regulation of cellular process 7.309E-3 4 796 3 6292
    negative regulation of DNA recombination 7.6087E-3 4 12 1 6292
    regulation of biological process 8.0789E-3 4 824 3 6292
    regulation of DNA recombination 9.5041E-3 4 15 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    histone binding 2.7517E-5 4 14 2 6292
    binding 1.7823E-3 4 1294 4 6292
    damaged DNA binding 6.9763E-3 4 11 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle