YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: QCR2

General Information:
Name(s) found: QCR2 / YPR191W [SGD]
Description(s) found:
Found 34 descriptions.
SHOW ALL
  • Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 368 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    mitochondrial respiratory chain complex III [IDALink to PubMed article]
    Biological Process: mitochondrial electron transport, ubiquinol to cytochrome c [IDALink to PubMed article]
    aerobic respiration [IMPLink to PubMed article]
    Molecular Function: ubiquinol-cytochrome-c reductase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSAARLQFA QGSVRRLTVS ARDAPTKIST LAVKVHGGSR YATKDGVAHL LNRFNFQNTN  60
   61 TRSALKLVRE SELLGGTFKS TLDREYITLK ATFLKDDLPY YVNALADVLY KTAFKPHELT 120
  121 ESVLPAARYD YAVAEQCPVK SAEDQLYAIT FRKGLGNPLL YDGVERVSLQ DIKDFADKVY 180
  181 TKENLEVSGE NVVEADLKRF VDESLLSTLP AGKSLVSKSE PKFFLGEENR VRFIGDSVAA 240
  241 IGIPVNKASL AQYEVLANYL TSALSELSGL ISSAKLDKFT DGGLFTLFVR DQDSAVVSSN 300
  301 IKKIVADLKK GKDLSPAINY TKLKNAVQNE SVSSPIELNF DAVKDFKLGK FNYVAVGDVS 360
  361 NLPYLDEL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) COR1 QCR2
    View Details (MIPS) Mewes HW, et al. (2004) COB COR1 CYT1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1
    View Details Krogan NJ, et al. (2006) COR1 OSH3 QCR2
    View Details Gavin AC, et al. (2006) COR1 QCR2
    View Details Gavin AC, et al. (2002) COR1 QCR2
    View Details Ho Y, et al. (2002) ACH1 ACO1 ADH2 ADH4 ADH6 AHA1 AIR2 APA1 ARP2 BCK1 BCY1 BIO3 BRX1 BUD7 CCT5 CDC33 COR1 CPR1 CPR6 DED1 DED81 DOG1 DUN1 ECM10 EGD1 EGD2 ENP1 ERG20 FET4 FOL2 FPR3 GAL7 GAR1 GCD11 GDI1 GND1 HAS1 HEM15 HTB2 IDH1 ILV5 IPP1 KIC1 KIN2 LHS1 LSM2 LSM8 LYS12 MAM33 MDH1 MIH1 MKK2 MKT1 MLH3 MRPS35 NAP1 NMD3 NPL3 OYE2 PDC6 PIL1 PIM1 PMA1 PRE3 PRP19 PRP8 PTC7 PWP1 QCR2 RAD26 RAD3 RCN2 RHR2 RPN12 RPN6 RPN8 RPT3 RRP42 SAP185 SAP190 SEC53 SES1 SIS1 SIT4 SKG3 SLT2 SMB1 SMK1 SNP1 SOD1 SRP1 STI1 TCP1 TEF4 TFP1 TIF1, TIF2 TIF6 TMA29 VAC14 YGL117W YJU2 YNK1 YSP2
    View Details Qiu et al. (2008) AAC3 ATP1 ATP15 ATP16 ATP17 ATP2 ATP4 ATP5 ATP6 ATP8 COB COR1 COX1 COX13 COX2 COX3 COX4 COX5A COX5B COX6 COX7 COX8 COX9 CYC1 CYT1 INH1 MCR1 OLI1 POR1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1 SDH1 SDH2 SDH3 SDH4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data QCR2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133]
    [158..217]    		 PSI-BLAST 10060.0 Cytochrome bc1 core subunit 2
    2 View Details [134..157]
    [218..368]    		 PSI-BLAST 10060.0 Cytochrome bc1 core subunit 2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquinol-cytochrome-c reductase activity
    		•  10.0305725791312 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  10.0305725791312 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  6.64269017601856 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  4.17510847735476 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  4.03221088799464 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.89224384280888 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  3.48526983761385 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.30443970063928 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.14174223148448 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.79848305609896 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.6563825341516 bayes_pls_golite062009
  • binding
    		•  1.92389577633668 bayes_pls_golite062009
  • catalytic activity
    		•  1.30647052031202 bayes_pls_golite062009
  • protein binding
    		•  1.16040346226904 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle