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Protein Overview: CG1718-PA

General Information:
Name(s) found: CG1718-PA / FBpp0076927 [FlyBase]
Description(s) found:
Found 14 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG1718 (CG1718, FBgn0031170). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:21163741..21171389. It has the cytological map location 19F3. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled to transmembrane movement of substances; transporter activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1713 amino acids

    Gene Ontology:
    Cellular Component: ATP-binding cassette (ABC) transporter complex [ISS]
    Biological Process: NONE FOUND
    Molecular Function: ATP binding [IEA]
    ATPase activity, coupled to transmembrane movement of substances [ISS]
    transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKVTNWDKF VLLLWKNWTL QWNHKWQMVI ELVLPAIFSL LLVLVRTLVD TEQKGVRYYN  60
   61 EQNLTDLNLL QKNGGFSKFE FILCYSPVNP VLKKLVEEAW QSLGKNKICE SENATQLELD 120
  121 TVSKNAFAGV QFDDAWANLT ENDPLPNDFH FALRFPAELR TATIAIANTW LTMRLFPTID 180
  181 LTGPRNEGDD DGGIPPGYLR EGFLPLQHSL SMAYLRQKSG EQDLPNVVMK RYPFPAYIFD 240
  241 PLLEGMSSIM SLIILLSFIY PCTYITKYIT AEKEKQLKEV MKIMGLSNWL HWTAWFVKSF 300
  301 IMLTISAILI AILVKINWSE DVAVLTHANF TALVFFLIIY IVSSICFCFM MATFFSRAST 360
  361 AAAVTGLIWF IAYIPYSFTI NSYDDLSLSS KLGWSLISNT AMGFGIKLIL GFEGTGEGLQ 420
  421 WSNFFTPVSV DDTLTLGAVM IMMLVSCVIY MIICLYVEQV MPGSFGVPRP WNFPFTREFW 480
  481 CGEREYTGVE DIPNGHVEQR DPKAFETEPE GKHIGLQMRH LKKRFGNKMV VKGLSMNMFE 540
  541 DEITVLLGHN GAGKTTTISM LTGMFPPTSG TAIINGSDIR TNIEGARMSL GICPQHNVLF 600
  601 DEMSVSNHIR FFSRMKGLRG KAVEQEVAKY LKMIELEDKA NVASSKLSGG MKRKLSVCCA 660
  661 LCGDTKVVLC DEPSSGMDPS ARRQLWDLLQ QEKVGRTLLL TTHFMDEADV LGDRIAIMCD 720
  721 GELKCQGTSF FLKKQYGSGY RLVSGVQNLF YGRCTYKTCD SLKICVKRDD CETNEVTALL 780
  781 NKYIPGLKPE CDIGAELSYQ LPDSASAKFE EMFGQLEEQS DELHLNGYGV GITSMEEVFM 840
  841 KVGAEKDNTG NIKDQHEIMN GGSGFRGEDD NESVQSDGIF SENRRLLQGL QLLSNQWKAM 900
  901 LLKKFLYTWR NKLLLLIQNI MPVFFVVVTI LIIKTQGTFQ ELKPITISLT QYPLAVTVLD 960
  961 RSNVQNGTGY EIANKYEDLA RSYGSNYGLE LTGTQGFEDY ILDLGKTIQV RINSRYLVAA1020
 1021 TITESKITAW LNNQALHTAP LTVNMVHNAI ADKLFGSSVK IQVTNAPLPY TTSTLLSQLS1080
 1081 TGNNLGTQLA SNLCFCMCFV SSIYILFLIK ERESRAKLLQ FVGGVKVWTF WLSQFICDFA1140
 1141 SYIVTALIVV ITIVCFQETG LSTFGELGRY YLLLLLFGFA VLPFIYIMSL FFREPATGFA1200
 1201 RVSIVNIFCG MALFIVVVVM SSELFDTKDT ADILGWIFRI FPHFSLAMSL NKVYTNTATR1260
 1261 NACAKAGALP PILLCELVPQ CCNLKPYFAW EEPGVLPETV YMAVTGVVFF LIIIVLEFRL1320
 1321 INELMFKIRQ LISKPPPPPT EGQLDDDVAN ERERILQMSS NELATKNLVL DRVTKYYGQF1380
 1381 MAVNQVSLCV QEVECFGLLG VNGAGKTTTF KMMTGDERIS SGAAYVQGLS LESNMNSIYK1440
 1441 MIGYCPQFDA LLDDLTGREV LRIFCMLRGV QESRIRQLSE DLAKSFGFMK HIDKQTHAYS1500
 1501 GGNKRKLSTA IAVIGSPSVI YLDEPTTGMD PAARRQLWNM VCRIRDSGKS IVLTSHSMEE1560
 1561 CEALCTRLAI MVNGEFKCIG STQHLKNKFS KGLILKIKVR RNLEALRQAR LSGGYARNPD1620
 1621 EQTVPAQMSQ RDIDAVKEFV ETEYPNSILQ EEYQGILTFY IPLTGVKWSR IFGLMESNRD1680
 1681 QLNVEDYSVS QTTLEEIFLE FAKYQREDTR ANQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] MSA 1.167988 View MSA. No confident structure predictions are available.
    2 View Details [187..385] deduced N/A No confident structure predictions are available.
    3 View Details [386..737] PSI-BLAST 33.69897 RNase-L Inhibitor
    4 View Details [738..865] PSI-BLAST 84.69897 Crystal structure of E. coli MalK in the nucleotide-free form
    5 View Details [866..949] deduced N/A No confident structure predictions are available.
    6 View Details [950..1035] deduced N/A No confident structure predictions are available.
    7 View Details [1036..1161] deduced N/A No confident structure predictions are available.
    8 View Details [1162..1366] deduced N/A No confident structure predictions are available.
    9 View Details [1367..1600] PSI-BLAST 60.69897 Crystal structure of ABC transporter ATP-binding protein (TM0544) from Thermotoga maritima at 2.10 A resolution
    10 View Details [1601..1713] PSI-BLAST 91.522879 No description for 2d62A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9
    Term Confidence Notes
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  6.58863529263644 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  6.58067278719409 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  6.57974651657836 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  6.57922174989907 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  6.57807080367604 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  6.48406410175216 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  6.48154954364331 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  6.40467109535527 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  6.40151534181487 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  6.38373914253885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  6.38247436082206 bayes_pls_golite062009
  • ATPase activity
    		•  6.30019941712404 bayes_pls_golite062009
  • peptide transporter activity
    		•  4.7442815698413 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  4.71935767060308 bayes_pls_golite062009
  • peptide-transporting ATPase activity
    		•  4.63590351019108 bayes_pls_golite062009
  • hydrolase activity
    		•  4.60957912556603 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  4.35344629015015 bayes_pls_golite062009
  • oligopeptide-transporting ATPase activity
    		•  4.09365342567844 bayes_pls_golite062009
  • ribonucleotide binding
    		•  3.79710854336074 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  3.7956093726294 bayes_pls_golite062009
  • ATP binding
    		•  3.78352939926331 bayes_pls_golite062009
  • purine nucleotide binding
    		•  3.74676466237472 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  3.73153142187361 bayes_pls_golite062009
  • nucleotide binding
    		•  3.71970404557651 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  3.66815111788068 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  3.57926427233638 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.4837867129694 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.35436118751376 bayes_pls_golite062009
  • phosphate transmembrane-transporting ATPase activity
    		•  3.20894563245332 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  3.14373643903738 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.13913638619234 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.08390071341252 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  3.05511942104215 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.9271291809464 bayes_pls_golite062009
  • branched-chain aliphatic amino acid transmembrane transporter activity
    		•  2.88795687640992 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.88476360771975 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  2.69529191205818 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.67957846350199 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  2.67815672695824 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.63419811368692 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.40292717311506 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  2.29486577878686 bayes_pls_golite062009
  • binding
    		•  2.0681607836408 bayes_pls_golite062009
  • oligopeptide transporter activity
    		•  2.05580564974083 bayes_pls_golite062009
  • molybdate ion transmembrane transporter activity
    		•  2.04724145339382 bayes_pls_golite062009
  • molybdate transmembrane-transporting ATPase activity
    		•  2.04724145339382 bayes_pls_golite062009
  • lipopolysaccharide transmembrane transporter activity
    		•  1.92426772294655 bayes_pls_golite062009
  • lipopolysaccharide-transporting ATPase activity
    		•  1.92426772294655 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • polysaccharide transmembrane transporter activity
    		•  1.87680514870933 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  1.82177108193332 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  1.76999970080179 bayes_pls_golite062009
  • protein transporter activity
    		•  1.71214667007262 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  1.59627719545436 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  1.57734504779864 bayes_pls_golite062009
  • phosphonate transmembrane transporter activity
    		•  1.40269234722336 bayes_pls_golite062009
  • carbohydrate-transporting ATPase activity
    		•  1.37859980472197 bayes_pls_golite062009
  • cation channel activity
    		•  1.33585529285301 bayes_pls_golite062009
  • carbohydrate-importing ATPase activity
    		•  1.27327946933978 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.23799860254751 bayes_pls_golite062009
  • potassium channel activity
    		•  1.20877745413881 bayes_pls_golite062009
  • sulfate transmembrane-transporting ATPase activity
    		•  1.1220946941463 bayes_pls_golite062009
  • dipeptide transporter activity
    		•  1.01130176523309 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  1.00384984515681 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • signal transducer activity
    		•  0.952448314982579 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.952448314982579 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.889208591820696 bayes_pls_golite062009
  • motor activity
    		•  0.87979065815418 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.871525745291603 bayes_pls_golite062009
  • ion channel activity
    		•  0.848261056209476 bayes_pls_golite062009
  • GTPase activity
    		•  0.83849854735032 bayes_pls_golite062009
  • channel activity
    		•  0.806331380134838 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.806331380134838 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.799997700906738 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  0.798934081014025 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.767424210804186 bayes_pls_golite062009
  • gated channel activity
    		•  0.650050847753837 bayes_pls_golite062009
  • vitamin transporter activity
    		•  0.492482773015923 bayes_pls_golite062009
  • L-aspartate transmembrane transporter activity
    		•  0.483217496906356 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.43042801294444 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  0.38711726712063 bayes_pls_golite062009
  • glucoside transmembrane transporter activity
    		•  0.31429820040527 bayes_pls_golite062009
  • maltose transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • alpha-glucoside transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • disaccharide transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • oligosaccharide transmembrane transporter activity
    		•  0.304521826432814 bayes_pls_golite062009
  • oligosaccharide-transporting ATPase activity
    		•  0.304521826432814 bayes_pls_golite062009
  • maltose-transporting ATPase activity
    		•  0.304521826432814 bayes_pls_golite062009
  • kinase activity
    		•  0.300431561463583 bayes_pls_golite062009
  • signal recognition particle binding
    		•  0.29390189699022 bayes_pls_golite062009
  • receptor activity
    		•  0.277332279568238 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.243026482777117 bayes_pls_golite062009
  • neutral amino acid transmembrane transporter activity
    		•  0.227570438294493 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.223761285614869 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  0.219473333671469 bayes_pls_golite062009
  • cholesterol transporter activity
    		•  0.20165628585345 bayes_pls_golite062009
  • protein kinase activity
    		•  0.194459978373898 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  0.147644650870465 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0689844878028699 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.0536898657672154 bayes_pls_golite062009
    10 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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