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Protein Overview: BAX_RAT

General Information:
Name(s) found: BAX_RAT [Swiss-Prot]
Description(s) found:
Found 11 descriptions.
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  • Apoptosis regulator BAX OS=Rattus norvegicus GN=Bax PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 192 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [UNKNOWN]
    cytosolic part [UNKNOWN]
    mitochondrial outer membrane [UNKNOWN][IDA][IEA]
    intracellular [UNKNOWN]
    endoplasmic reticulum membrane [UNKNOWN]
    soluble fraction [UNKNOWN]
    mitochondrial permeability transition pore complex [UNKNOWN]
    mitochondrial membrane [UNKNOWN][IMP]
    cytoplasm [UNKNOWN][IDA][IMP]
    mitochondrion [UNKNOWN][IDA]
    membrane [IEA]
    integral to membrane [IEA]
    cytosol [UNKNOWN][IDA]
    Biological Process: male gonad development [UNKNOWN]
    retina development in camera-type eye [UNKNOWN]
    post-embryonic development [UNKNOWN]
    spermatid differentiation [UNKNOWN]
    response to axon injury [UNKNOWN]
    induction of apoptosis by extracellular signals [UNKNOWN]
    response to toxin [UNKNOWN]
    glycosphingolipid metabolic process [UNKNOWN]
    B cell homeostatic proliferation [UNKNOWN]
    induction of apoptosis in response to chemical stimulus [UNKNOWN]
    positive regulation of developmental pigmentation [UNKNOWN]
    kidney development [UNKNOWN]
    induction of apoptosis [UNKNOWN][IMP]
    [NOT]regulation of mitochondrial membrane potential [UNKNOWN]
    apoptosis [UNKNOWN][IEP][IMP]
    nuclear fragmentation during apoptosis [UNKNOWN]
    negative regulation of peptidyl-serine phosphorylation [UNKNOWN]
    activation of caspase activity [UNKNOWN]
    regulation of cell cycle [UNKNOWN]
    response to gamma radiation [UNKNOWN]
    glial cell apoptosis [IEP]
    neuron apoptosis [UNKNOWN]
    response to ionizing radiation [UNKNOWN]
    germ cell programmed cell death [UNKNOWN]
    response to cocaine [IEP]
    retinal cell programmed cell death [UNKNOWN]
    protein homooligomerization [UNKNOWN]
    fertilization [UNKNOWN]
    regulation of apoptosis [IEA]
    cellular respiration [IDA]
    cerebral cortex development [UNKNOWN]
    development of secondary sexual characteristics [UNKNOWN]
    response to DNA damage stimulus [UNKNOWN]
    activation of caspase activity by cytochrome c [UNKNOWN][TAS]
    regulation of mitochondrial membrane permeability [UNKNOWN]
    negative regulation of survival gene product expression [UNKNOWN]
    induction of apoptosis by intracellular signals [UNKNOWN]
    response to corticosterone stimulus [IEP]
    cleavage of lamin [UNKNOWN]
    regulation of caspase activity [UNKNOWN]
    transformed cell apoptosis [UNKNOWN]
    induction of retinal programmed cell death [UNKNOWN]
    release of cytochrome c from mitochondria [UNKNOWN][IMP]
    limb morphogenesis [UNKNOWN]
    regulation of nitrogen utilization [UNKNOWN]
    cell proliferation [UNKNOWN]
    vagina development [UNKNOWN]
    response to salt stress [UNKNOWN]
    negative regulation of cell proliferation [UNKNOWN]
    reduction of endoplasmic reticulum calcium ion concentration [UNKNOWN]
    nervous system development [UNKNOWN]
    response to wounding [UNKNOWN]
    myeloid cell homeostasis [UNKNOWN]
    hypothalamus development [UNKNOWN]
    odontogenesis of dentine-containing tooth [UNKNOWN]
    positive regulation of neuron apoptosis [UNKNOWN]
    negative regulation of neuron apoptosis [UNKNOWN]
    neuron migration [UNKNOWN]
    sex differentiation [UNKNOWN]
    apoptotic mitochondrial changes [UNKNOWN]
    protein insertion into mitochondrial membrane during induction of apoptosis [UNKNOWN]
    negative regulation of fibroblast proliferation [UNKNOWN]
    regulation of mammary gland epithelial cell proliferation [UNKNOWN]
    cellular response to UV [UNKNOWN]
    negative regulation of anti-apoptosis [UNKNOWN]
    germ cell development [UNKNOWN]
    Sertoli cell proliferation [UNKNOWN]
    positive regulation of apoptosis involved in mammary gland involution [UNKNOWN]
    spermatogenesis [UNKNOWN]
    mitochondrial fusion [UNKNOWN]
    regulation of protein heterodimerization activity [UNKNOWN]
    response to copper ion [IEP]
    regulation of protein homodimerization activity [UNKNOWN]
    mitochondrial fragmentation involved in apoptosis [UNKNOWN]
    positive regulation of release of sequestered calcium ion into cytosol [UNKNOWN]
    B cell negative selection [UNKNOWN]
    inner mitochondrial membrane organization [IDA]
    outer mitochondrial membrane organization [IDA]
    B cell homeostasis [UNKNOWN]
    ovarian follicle development [UNKNOWN][IEP]
    B cell apoptosis [UNKNOWN]
    response to acid [UNKNOWN]
    leukocyte homeostasis [UNKNOWN]
    blood vessel remodeling [UNKNOWN]
    T cell homeostatic proliferation [UNKNOWN]
    homeostasis of number of cells within a tissue [UNKNOWN]
    DNA fragmentation involved in apoptosis [UNKNOWN]
    response to drug [IEP]
    post-embryonic camera-type eye morphogenesis [UNKNOWN]
    homeostasis of number of cells [UNKNOWN]
    positive regulation of apoptosis [UNKNOWN]
    establishment or maintenance of transmembrane electrochemical gradient [UNKNOWN]
    positive regulation of B cell apoptosis [UNKNOWN]
    positive regulation of calcium ion transport into cytosol [UNKNOWN]
    apoptosis in response to endoplasmic reticulum stress [UNKNOWN]
    release of matrix enzymes from mitochondria [UNKNOWN]
    Molecular Function: BH domain binding [IPI]
    heat shock protein binding [IPI]
    BH3 domain binding [UNKNOWN]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN][IPI]
    protein homodimerization activity [UNKNOWN]
    protein heterodimerization activity [UNKNOWN][IPI]
    chaperone binding [IPI]
    lipid binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGSGEQLGG GGPTSSEQIM KTGAFLLQGF IQDRAGRMAG ETPELTLEQP PQDASTKKLS  60
   61 ECLRRIGDEL DSNMELQRMI ADVDTDSPRE VFFRVAADMF ADGNFNWGRV VALFYFASKL 120
  121 VLKALCTKVP ELIRTIMGWT LDFLRERLLV WIQDQGGWDG LLSYFGTPTW QTVTIFVAGV 180
  181 LTASLTIWKK MG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle