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Any process that activates or increases the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group. Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, mediated by cytochrome c. Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. Cell death resulting from activation of endogenous cellular processes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: activation of caspase activity
Acc: GO:0006919
Aspect: Biological Process
Desc: Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
Synonyms:
  • caspase activation
Proteins in PDR annotated with:
   This term: 96 [Search]
   Term or descendants: 107 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006919 - activation of caspase activity (interactive image map)
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