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Any process that activates or increases the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. Any process that modulates the occurrence or rate of cell death by apoptosis. Any process that stops, prevents or reduces the frequency, rate or extent of caspase activity. Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of caspase activity
Acc: GO:0043281
Aspect: Biological Process
Desc: Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
Synonyms:
  • regulation of caspase activation
  • GO:0043026
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 210 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043281 - regulation of caspase activity (interactive image map)
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