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The process of apoptosis in glial cells. A biological process that results in permanent cessation of all vital functions of a cell. The conversion of proteins that induce or sustain apoptosis to an active form. Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. Any process that activates or increases the frequency, rate or extent of cell death by apoptosis. Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. The process of apoptosis in myeloid cells. Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix. The process of apoptosis in transformed cells, cells that have undergone changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. Any process that modulates the occurrence or rate of cell death by apoptosis. The process of apoptosis that contributes to the shaping of an anatomical structure. The process of apoptosis in inflammatory cells, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage. The process of apoptosis in cells infected with a virus. Cell death resulting from activation of endogenous cellular processes. The process of apoptosis in neurons, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. The morphological and physiological alterations undergone by mitochondria during apoptosis. Ovarian follicle demise mediated by apoptosis. Apoptosis that occurs in response to a stimulus indicating endoplasmic reticulum (ER) stress. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. The process of apoptosis in a lymphocyte. A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. The process by which nurse cells undergo apoptosis. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptosis.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: apoptosis
Acc: GO:0006915
Aspect: Biological Process
Desc: A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell.
Synonyms:
  • apoptotic cell death
  • signaling (initiator) caspase activity
  • GO:0008632
  • programmed cell death by apoptosis
  • apoptotic programmed cell death
  • type I programmed cell death
  • apoptotic program
Proteins in PDR annotated with:
   This term: 907 [Search]
   Term or descendants: 2314 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006915 - apoptosis (interactive image map)

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