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Protein Overview: SEN15

General Information:
Name(s) found: SEN15 / YMR059W [SGD]
Description(s) found:
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  • gi|99030929|ref|NP_013775.2| Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen15p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|3915878|sp|Q04675.2|SEN15_YEAST RecName: Full=tRNA-splicing endonuclease subunit SEN15; AltName: Full=tRNA-intron endonuclease SEN15; AltName: Full=Splicing endonuclease of 15 kDa [NCBI NR]
  • tRNA-splicing endonuclease subunit SEN15 OS=Saccharomyces cerevisiae GN=SEN15 PE=1 SV=2 [Swiss-Prot]
  • (Q04675) tRNA-splicing endonuclease subunit SEN15 (tRNA-intron endonuclease SEN15) (Splicing endonuclease of 15 kDa) [Swiss-Prot]
  • Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p [SGD]
  • (Q04675) tRNA-splicing endonuclease subunit SEN15 (EC 3.1.27.9) (tRNA-intron endonuclease) [4932.FASTACCERV.txt]
  • tRNA-splicing endonuclease subunit SEN15 (tRNA-intron endonuclease SEN15) (Splicing endonuclease of 15 kDa) [nrdb_11152004_Chlamydomonas]
  • SEN15 SGDID:S000004663, Chr XIII from 391098-391484, Verified ORF, "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" [yeast-contam.fasta]
  • Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen15p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • tRNA-splicing endonuclease subunit SEN15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEN15 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • SEN15 SGDID:S000004663, Chr XIII from 391099-391485, Genome Release 64-1-1, Verified ORF, "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" [yeast-030211-contam.fasta]
  • SEN15 SGDID:S000004663, Chr XIII from 391099-391485, Genome Release 64-2-1, Verified ORF, "Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease is composed of Sen2p, Sen15p, Sen34p, and Sen54p" [20141208_orf_trans.fasta]
  • YMR059W SGDID:S000004663, Chr XIII from 391099-391485, Genome Release 64-1-1, Verified ORF, "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 128 amino acids

    Gene Ontology:
    Cellular Component: nuclear inner membrane [TASLink to PubMed article]
    tRNA-intron endonuclease complex [TASLink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    Biological Process: tRNA splicing, via endonucleolytic cleavage and ligation [TASLink to PubMed article]
    Molecular Function: tRNA-intron endonuclease activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTDIISLV KNNLLYFQMW TEVEILQDDL SWKGNSLRLL RGRPPHKLSN DVDTEHENSL  60
   61 SSPRPLEFIL PINMSQYKEN FLTLECLSQT FTHLCSPSTE RILLAIINDD GTIVYYFVYK 120
  121 GVRKPKRN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) LOS1 SEN15 SEN2 SEN34 SEN54 STP1 STP2 STP3 STP4 TPT1 TRL1
    View Details Ho Y, et al. (2002) AAT2 ACH1 ACO1 AFR1 AHP1 ARC1 ARF1 ATP3 CAR2 CDC33 CLU1 COF1 COR1 CPR1 CYR1 CYS4 EGD1 ERG13 ERG6 FPR1 FRS2 GND1 GND2 GRX1 GUS1 HEF3 HHF1, HHF2 LRO1 LSP1 MET6 NTF2 OLA1 OYE2 PFK1 PIL1 PRM2 RNR2 RSN1 SAH1 SCP160 SEC53 SEN15 SES1 SNU13 SOD1 TEF4 THS1 TIF1, TIF2 TMA19 TSA2 UBA1 VMA4 VMA5 WTM1 YNK1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SEN15 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] FFAS03 2.9 No description for 2gw6A was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle