YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: CCL1

General Information:
Name(s) found: CCL1 / YPR025C [SGD]
Description(s) found:
Found 27 descriptions.
SHOW ALL
  • Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 393 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    holo TFIIH complex [TASLink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter, mitotic [TASLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [TASLink to PubMed articleLink to PubMed article]
    Molecular Function: cyclin-dependent protein kinase regulator activity [TASLink to PubMed article]
    general RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDIQLNGKS TLDTPSATMS AKEKEAKLKS ADENNKPPNY KRISDDDLYR HSSQYRMWSY  60
   61 TKDQLQEKRV DTNARAIAYI EENLLKFREA HNLTEEEIKV LEAKAIPLTM EEELDLVNFY 120
  121 AKKVQVIAQH LNLPTEVVAT AISFFRRFFL ENSVMQIDPK SIVHTTIFLA CKSENYFISV 180
  181 DSFAQKAKST RDSVLKFEFK LLESLKFSLL NHHPYKPLHG FFLDIQNVLY GKVDLNYMGQ 240
  241 IYDRCKKRIT AALLTDVVYF YTPPQITLAT LLIEDEALVT RYLETKFPSR EGSQESVPGN 300
  301 EKEEPQNDAS TTEKNKEKST ESEEYSIDSA KLLTIIRECK SIIEDCKPPS TEEAKKIAAK 360
  361 NYYCQNPSTL IQKLKRKLNG EDTSSTVEKK QKT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CCL1 KIN28 TFB3
    View Details (MIPS) Mewes HW, et al. (2004) CCL1 KIN28 RAD2 RAD3 SSL1 SSL2 TFB1 TFB2 TFB3 TFB4
    View Details Krogan NJ, et al. (2006) CCL1 ESP1 KIN28 RAD3 SSL1 TFB1 TFB3 TFB4
    View Details Gavin AC, et al. (2002) CCL1 DCS2 FAP1 FPR1 KAP95 KIN28 MRPS28 SPT7 SSL1 TFA1 TFB1 TFB3 TFB4 TIF6
    View Details Ho Y, et al. (2002) AAC3 ACO1 ATP3 CCL1 HOR2 HXT6 LSC1 MET18 RAD3 RHR2 RPN1 RPT3 TFP1 THI22
    View Details Qiu et al. (2008) CCL1 KIN28 RAD2 RAD3 SSL1 SSL2 TAF1 TFB2 TFB3 TFB4 TFB5

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PRP16 CCL1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data CCL1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212]
    [347..393]    		 PSI-BLAST 279.218487 Cyclin H (mcs2)
    2 View Details [213..346] PSI-BLAST 279.218487 Cyclin H (mcs2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  8.12427628405368 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  3.42865021590497 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  2.96093967361332 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.795846725429 bayes_pls_golite062009
  • kinase regulator activity
    		•  2.79045953713534 bayes_pls_golite062009
  • protein binding
    		•  2.52152158357422 bayes_pls_golite062009
  • binding
    		•  2.4204867358489 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.04886889839181 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.00665312545368 bayes_pls_golite062009
  • DNA binding
    		•  1.94297811210385 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.69439693414478 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.42956126861466 bayes_pls_golite062009
  • transcription activator activity
    		•  1.39881476204374 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21921365719206 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.907121673967035 bayes_pls_golite062009
  • transcription factor binding
    		•  0.749278791251235 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.729629809946521 bayes_pls_golite062009
  • hydrolase activity
    		•  0.62079213929979 bayes_pls_golite062009
  • positive transcription elongation factor activity
    		•  0.42590121577004 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.36347576272001 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.138191616709499 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle