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View Structure Prediction Details

Protein: CCL1
Organism: Saccharomyces cerevisiae
Length: 393 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCL1.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 6.0E-92 [7..363] [100..459]
CCNB1_SOYBN - G2/mitotic-specific cyclin S13-6 OS=Glycine max PE=2 SV=1
 2.0E-88 [6..354] [108..452]
CCNB2_RANJA - G2/mitotic-specific cyclin-B2 OS=Rana japonica GN=CCNB2 PE=2 SV=1
 3.0E-88 [5..336] [51..372]
gi|197693462 - gi|197693462|gb|ACH71406.1| B2 cyclin [Dicistronic cloning vector pXL-Id]
CCNB2_XENLA - G2/mitotic-specific cyclin-B2 OS=Xenopus laevis GN=ccnb2 PE=1 SV=1
gi|197693458 - gi|197693458|gb|ACH71403.1| B2 cyclin [Dicistronic cloning vector pXLJ Con]
 4.0E-87 [7..338] [56..376]
CCNB1, CGB1 - chorionic gonadotropin, beta polypeptide 1, cyclin B1
gi|123990181 - gi|123990181|gb|ABM83901.1| cyclin B1 [synthetic construct]
 4.0E-87 [25..357] [105..433]
gi|33416373, gi|... - gi|45501371|gb|AAH67192.1| Cyclin B1 [Danio rerio], gi|33416373|gb|AAH55553.1| Cyclin B1 [Danio reri...
 1.0E-86 [1..348] [38..394]
gi|13605768 - gi|13605768|gb|AAK32876.1| cyclin B2 [Rana dybowskii]
 2.0E-86 [5..336] [51..374]
CCNB1_MESAU - G2/mitotic-specific cyclin-B1 OS=Mesocricetus auratus GN=CCNB1 PE=2 SV=1
 3.0E-86 [6..336] [83..409]

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Predicted Domain #1
Region A:
Residues: [1-212] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDIQLNGKS TLDTPSATMS AKEKEAKLKS ADENNKPPNY KRISDDDLYR HSSQYRMWSY  60
   61 TKDQLQEKRV DTNARAIAYI EENLLKFREA HNLTEEEIKV LEAKAIPLTM EEELDLVNFY 120
  121 AKKVQVIAQH LNLPTEVVAT AISFFRRFFL ENSVMQIDPK SIVHTTIFLA CKSENYFISV 180
  181 DSFAQKAKST RDSVLKFEFK LLESLKFSLL NH

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [347-393] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPPSTEEAKK IAAKNYYCQN PSTLIQKLKR KLNGEDTSST VEKKQKT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 279.218487
Match: 1jkw__
Description: Cyclin H (mcs2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 8.12427628405368 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 3.42865021590497 bayes_pls_golite062009
protein kinase regulator activity 2.96093967361332 bayes_pls_golite062009
transcription regulator activity 2.795846725429 bayes_pls_golite062009
kinase regulator activity 2.79045953713534 bayes_pls_golite062009
protein binding 2.52152158357422 bayes_pls_golite062009
binding 2.4204867358489 bayes_pls_golite062009
nucleic acid binding 2.04886889839181 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.00665312545368 bayes_pls_golite062009
DNA binding 1.94297811210385 bayes_pls_golite062009
transcription elongation regulator activity 1.69439693414478 bayes_pls_golite062009
transcription repressor activity 1.42956126861466 bayes_pls_golite062009
transcription activator activity 1.39881476204374 bayes_pls_golite062009
transcription factor activity 1.21921365719206 bayes_pls_golite062009
sequence-specific DNA binding 0.907121673967035 bayes_pls_golite062009
transcription factor binding 0.749278791251235 bayes_pls_golite062009
enzyme regulator activity 0.729629809946521 bayes_pls_golite062009
hydrolase activity 0.62079213929979 bayes_pls_golite062009
positive transcription elongation factor activity 0.42590121577004 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.36347576272001 bayes_pls_golite062009
transcription coactivator activity 0.138191616709499 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [213-346] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPYKPLHGFF LDIQNVLYGK VDLNYMGQIY DRCKKRITAA LLTDVVYFYT PPQITLATLL  60
   61 IEDEALVTRY LETKFPSREG SQESVPGNEK EEPQNDASTT EKNKEKSTES EEYSIDSAKL 120
  121 LTIIRECKSI IEDC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 279.218487
Match: 1jkw__
Description: Cyclin H (mcs2)
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle