Protein Overview: BBP1

General Information:
Name(s) found:	BBP1 / YPL255W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6325000\|ref\|NP_015068.1\| Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions [NCBI NR] gi\|51013489\|gb\|AAT93038.1\| YPL255W [Saccharomyces cerevisiae] [NCBI NR] gi\|2498178\|sp\|Q12365.1\|BBP1_YEAST RecName: Full=Protein BBP1 [NCBI NR] pir\|\|S61566 BBP1 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1370524\|emb\|CAA97981.1\| BBP1 [Saccharomyces cerevisiae] [NCBI NR] gi\|1113129\|emb\|CAA63347.1\| BBP1 [Saccharomyces cerevisiae] [NCBI NR] Protein BBP1 OS=Saccharomyces cerevisiae GN=BBP1 PE=1 SV=1 [Swiss-Prot] BBP1 Cell division control protein [mips] Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p [SGD] (Q12365) BBP1 protein [4932.FASTACCERV.txt] Chr XVI from 67725-68882 [hmr_yeast5_DM3-1_pombe.fasta] BBP1, Chr XVI from 67725-68882 [yeast_orfs2] BBP1 SGDID:S0006176, Chr XVI from 67725-68882, Verified ORF [yeastflysequest.fasta] Bbp1p [Saccharomyces cerevisiae]gi\|51013489\|gb\|AAT93038.1\| YPL255W [Saccharomyces cerevisiae]gi\|1370524\|emb\|CAA97981.1\| BBP1 [Saccharomyces cerevisiae]gi\|1113129\|emb\|CAA63347.1\| BBP1 [Saccharomyces cerevisiae]gi\|2498178\|sp\|Q12365\|BBP1_YEAST BBP1 prote [nrdb_11152004_Chlamydomonas] BBP1 SGDID:S000006176, Chr XVI from 67725-68882, Verified ORF, "Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Ka [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Protein BBP1 [nr-271106-contam.fasta] BBP1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YPL255W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p; Bbp1p [Saccharomyc [nr-271106-contam.fasta] BBP1 SGDID:S000006176, Chr XVI from 67725-68882, Verified ORF, "Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Spindle pole component BBP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BBP1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] BBP1 SGDID:S000006176, Chr XVI from 67725-68882, Genome Release 64-1-1, Verified ORF, "Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p" [yeast-030211-contam.fasta] BBP1 SGDID:S000006176, Chr XVI from 67725-68882, Genome Release 64-2-1, Verified ORF, "Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p" [20141208_orf_trans.fasta] YPL255W SGDID:S000006176, Chr XVI from 67725-68882, Genome Release 64-1-1, Verified ORF, "Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	385 amino acids
Gene Ontology:
Cellular Component:	spindle pole body [IDA]
Biological Process:	microtubule nucleation [IPI] spindle pole body duplication in nuclear envelope [IMP]
Molecular Function:	structural constituent of cytoskeleton [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQEDNTGGG GIFGLFKWTK DALFGTDISP SMKYKDQEER RDRSRYAQDD TNFSMKFGND  60
   61 SNRRSTNLSR SNSWSGLDST LHRKYELLPE YNENGFNSIV NGDHHSKERI RSLRSPAPIV 120
  121 PREPLRNEPT DTFGHRLHTK RRTINELSNS QIPFIPPQED DPLLSKLFNK DGVNEVRRSP 180
  181 YKLSVKDIPG KFPSPLTKRD EIDNYYVRDE DACHKNREYK KAYFDLFAQM DLNSRDLEDL 240
  241 CEDVREQREQ FHRNEQTYKQ AYEEMRAELV NELKKSKTLF ENYYSLGQKY KSLKKVLDQT 300
  301 ISHEAELATS RERLYQEEDL KNFEIQTLKQ RLSDLELKYT NLQIEKDMQR DNYESEIHDL 360
  361 LLQLSLRNNE RKDTSAGSNI FSTGQ

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		BBP1 CDC31 CMD1 CNM67 KAR1 NUD1 SPC105 SPC110 SPC24 SPC25 SPC29 SPC42 SPC72
View Details	Qiu et al. (2008)		ARP10 BBP1 CNM67 DAD2 DAM1 DUO1 KAR1 KAR3 MPS2 NDC1 NUF2 SFI1 SGO1 SPC105 SPC110 SPC19 SPC24 SPC25 SPC29 SPC34 SPC42 SPC72 SPC97 SPC98 STU1 STU2 TID3 TUB4

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#33 Asynchronous SPB prep	Keck JM, et al. (2011)
View Run	MLP2	#19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2	Keck JM, et al. (2011)
View Run	MLP2	#21 Asynchronous Prep2-IMAC Phosphopeptide enrichment A1	Keck JM, et al. (2011)
View Run	MLP2	#22 Asynchronous Prep2-IMAC Phosphopeptide enrichment B1-2	Keck JM, et al. (2011)
View Run	MLP2	#34 Asynchronous SPB prep	Keck JM, et al. (2011)
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#35 Asynchronous SPB prep	Keck JM, et al. (2011)
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#14 Mitotic Prep2-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#13 Mitotic Prep2-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#10 Mitotic Prep1-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#02 Alpha Factor Prep1-TiO2 enriched, new search criteria	Keck JM, et al. (2011)
View Run	MLP2	#30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#11 Mitotic Prep1-TiO2 enriched, new search criteria	Keck JM, et al. (2011)
View Run	MLP2	#01 Alpha factor Prep1-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#28 Asynchronous Prep5-TiO2 Phosphopeptide Enrichment	Keck JM, et al. (2011)
View Run	MLP2	#06 Alpha Factor Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#08 Alpha Factor Prep4-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#16 Mitotic-New search criteria	Keck JM, et al. (2011)
View Run	MLP2	#15 Mitotic 2nd-TiO2 enriched, new search criteria	Keck JM, et al. (2011)
View Run	MLP2	#19b Asynchronous Prep1-new search criteria	Keck JM, et al. (2011)
View Run	MLP2	#05 Alpha Factor Prep2-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#07 Alpha Factor Prep3-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#09 Alpha Factor Prep4-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	None Entered	#17 Mitotic Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	None Entered	#18 Mitotic Prep4-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#19a Asynchronous Prep1-new search criteria	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	BBP1 and SPC42	Huh WK, et al. (2003)
View Data	BBP1	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..232]	deduced	N/A	No confident structure predictions are available.
2	View Details	[233..385]	MSA	1.002963	View MSA. No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: BBP1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: