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Protein Overview: SFI1

General Information:
Name(s) found: SFI1 / YLL003W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the half-bridge of the SPB, required for progression through G(2)-M transition, has similarity to Xenopus laevis XCAP-C [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 946 amino acids

    Gene Ontology:
    Cellular Component: half bridge of spindle pole body [IDALink to PubMed article]
    Biological Process: G2/M transition of mitotic cell cycle [IMPLink to PubMed article]
    spindle pole body duplication in nuclear envelope [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKFGTTNKS TENLLRDKFV PETSPTNIPT DVLIKQGQIT DSTESLIHGG AERYIVNALK  60
   61 PIELNKTEGF FEDPPFHLPS PPVDSTNLEY EDVTDLPKNG LRYDLNDISV EVIEDLYRQI 120
  121 EAFLVHFKLS RSFLQIFKNY VNILIQEGIN PLRDEYFTIL EDELKGFFTF NSVIEEILEI 180
  181 FLIHPRNKFI ALSLAEYTYA KNKIRRHFNH WKTVCELNEE ANRFANQAKL RVQEAVFYIW 240
  241 SDKTLKYSQM ANDEAESFRN TWLLFRSFQQ WITLTQTLKE QSRLADQAFL NKMFRKILKA 300
  301 QEHWKHLETV NTDNIKKIFL RTTFHIWKLR HKEINYHGLE RRIFERIKQK VINYEYNKSI 360
  361 AEKVRSFSLQ RKYLNKWEKK NIENEDKLGA LYELENKFIK QKFFRKLNRS FQHSQQEAIA 420
  421 KSKLNQTLLR CVFEKMWLKR FEDHLHLYSI VSLKEANLVK RIFHSWKKLL YIDLKASDYS 480
  481 RTNLLKSSLR SWKLEVKLKI FEQKCKKSIQ ASAYRTWRKR IQYGKISSEH VKTAFCAKYL 540
  541 GVWKRRMLQM NSMNDEASKF YEEGLVNECL AIWKERLIKT KELEDRYNFL CKTHAILTVK 600
  601 RTLMHIDNVH LLYTKLAPSM DRVKLSKAFL KWRKATRFKV RHKLNDILHV YEKSKERELQ 660
  661 SQLFNAWRNR FCFYTEECNI QAISKRNYQL EKMVLKKFRE RLLEIVKSEE LADEVREEFV 720
  721 LVKTFYIWKT HLDEIFYMST LLEQSEANKQ FIITSKFLKM WSLRFLKIKR NDETVEVFRH 780
  781 RWDRATVRGL LLLWKNRSDS SPKRRKDFNL KHELKTPIRS DSQNASTIPG SERIKQHRME 840
  841 AMKSHYSRAR RAIPSPVKSS SVLDSTAKKQ INLESTTGLN GSPTRGKPLR YSPRRTTRNM 900
  901 PSKVDHIDFG RIPAVPFSLS ANSPKIDQDM DYIREHDKSP LSRKRQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) BBP1 CDC31 CIK1 HSK3 KAR1 MPS2 MPS3 NBP1 SFI1 SPC105 SPC19 SPC29 SPC42

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #02 Alpha Factor Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)
    View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)
    View Run MLP2 #16 Mitotic-New search criteria Keck JM, et al. (2011)
    View Run MLP2 #15 Mitotic 2nd-TiO2 enriched, new search criteria Keck JM, et al. (2011)
    View Run MLP2 #19b Asynchronous Prep1-new search criteria Keck JM, et al. (2011)
    View Run None Entered #17 Mitotic Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run None Entered #18 Mitotic Prep4-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #19a Asynchronous Prep1-new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SFI1 Huh WK, et al. (2003)
    View Data SFI1 and SPC42 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] deduced N/A No confident structure predictions are available.
    2 View Details [97..260] ab initio 12.7 No description for 1qgkA was found.
    3 View Details [261..454] ab initio 12.7 No description for 1qgkA was found.
    4 View Details [455..546] ab initio 12.7 No description for 1qgkA was found.
    5 View Details [547..655] ab initio 12.7 No description for 1qgkA was found.
    6 View Details [656..813] ab initio 12.7 No description for 1qgkA was found.
    7 View Details [814..946] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle