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Protein Overview: MRPS12

General Information:
Name(s) found: MRPS12 / YNR036C [SGD]
Description(s) found:
Found 32 descriptions.
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  • Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 153 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial small ribosomal subunit [ISSLink to PubMed article]
    ribosome [IDALink to PubMed article]
    Biological Process: translation [ISSLink to PubMed article]
    Molecular Function: structural constituent of ribosome [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRFMSNTW CTPLRQAQRL FSSTTTMQAT LNQIKRGSGP PRRKKISTAP QLDQCPQRKG  60
   61 VVLRVMVLKP KKPNSAQRKA CRVRLTNGNV VSAYIPGEGH DAQEHSIVYV RGGRCQDLPG 120
  121 VKYHVIRGAG DLSGVVNRIS SRSKYGAKKP SKS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CBF1 FYV4 MAM33 MRP1 MRP10 MRP17 MRP21 MRP4 MRP51 MRPL8 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS9 NAM9 NCL1 PET123 RIB4 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 SVL3 SWS2 YDR124W YJR096W YKL151C YSP1
    View Details Qiu et al. (2008) IMG1 MRP1 MRP10 MRP13 MRP17 MRP2 MRP21 MRP4 MRP49 MRP51 MRP7 MRPL1 MRPL10 MRPL11 MRPL16 MRPL19 MRPL20 MRPL22 MRPL23 MRPL24 MRPL27 MRPL28 MRPL3 MRPL31 MRPL35 MRPL36 MRPL38 MRPL39 MRPL4 MRPL40 MRPL6 MRPL7 MRPL8 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 PPE1 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 RTC6 SWS2 VAR1 YML6 YMR31

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] PSI-BLAST 326.522879 No description for 1l1uL_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of ribosome
    		•  7.45319063235379 bayes_pls_golite062009
  • structural molecule activity
    		•  6.87843523680097 bayes_pls_golite062009
  • misfolded RNA binding
    		•  4.4877915495248 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.7132569326175 bayes_pls_golite062009
  • RNA binding
    		•  3.30183895019873 bayes_pls_golite062009
  • DNA binding
    		•  2.94486937698231 bayes_pls_golite062009
    		• 2.80746531284205 bayes_pls_golite062009
  • binding
    		•  2.40532042551671 bayes_pls_golite062009
  • mRNA binding
    		•  1.65819015373151 bayes_pls_golite062009
  • translation regulator activity
    		•  1.46320772716954 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.40718318783582 bayes_pls_golite062009
  • translation initiation factor activity
    		•  1.27539679024898 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.24522359765541 bayes_pls_golite062009
  • protein binding
    		•  1.20309946451799 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.10289736160471 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.96886436248958 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.91658673456122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.672797026326101 bayes_pls_golite062009
  • transcription activator activity
    		•  0.581984534552921 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.474251377131502 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.47336621289748 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.47336621289748 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.438266295385131 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.39131721416336 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.3506031439435 bayes_pls_golite062009
  • nuclease activity
    		•  0.17660139576327 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.1542034177713 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.1542034177713 bayes_pls_golite062009
  • transcription factor binding
    		•  0.132487446755259 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.0717589400404304 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

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    Created and Maintained by: Michael Riffle