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View Structure Prediction Details

Protein: MRPS12
Organism: Saccharomyces cerevisiae
Length: 153 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPS12.

Description E-value Query
Range		 Subject
Range
RT12_YEAST - 37S ribosomal protein S12, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
gi|190408965 - gi|190408965|gb|EDV12230.1| 30S ribosomal protein S12 [Saccharomyces cerevisiae RM11-1a]
MRPS12 - Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to ...
gi|151944565 - gi|151944565|gb|EDN62843.1| conserved protein [Saccharomyces cerevisiae YJM789]
 8.0E-54 [1..153] [1..153]
RT12_OENEH - 40S ribosomal protein S12, mitochondrial OS=Oenothera elata subsp. hookeri GN=RPS12 PE=2 SV=1
 4.0E-53 [8..153] [44..188]
RR12_MARPO - 30S ribosomal protein S12, chloroplastic OS=Marchantia polymorpha GN=rps12 PE=3 SV=1
 2.0E-49 [28..151] [1..123]
gi|15889246, gi|... - gi|15889246|ref|NP_354927.1| 30S ribosomal protein S12 [Agrobacterium tumefaciens str. C58], gi|1515...
gi|25294702 - gi|25294702|pir||G97594 hypothetical protein AGR_C_3561 [imported] - Agrobacterium tumefaciens (stra...
 3.0E-49 [14..151] [1..136]
RS12_RALPJ - 30S ribosomal protein S12 OS=Ralstonia pickettii (strain 12J) GN=rpsL PE=3 SV=1
RS12_RALSO - 30S ribosomal protein S12 OS=Ralstonia solanacearum (strain GMI1000) GN=rpsL PE=3 SV=1
RS12_RALSO - 30S ribosomal protein S12 OS=Ralstonia solanacearum GN=rpsL PE=3 SV=1
gi|207744582, gi... - gi|207744582|ref|YP_002260974.1| 30s ribosomal protein s12 [Ralstonia solanacearum IPO1609], gi|2065...
gi|206587073, gi... - gi|207721904|ref|YP_002252342.1| 30s ribosomal protein s12 [Ralstonia solanacearum MolK2], gi|206587...
gi|83749346, gi|... - gi|83749346|ref|ZP_00946342.1| SSU ribosomal protein S12P [Ralstonia solanacearum UW551], gi|8372397...
gi|241664537, gi... - gi|241664537|ref|YP_002982897.1| ribosomal protein S12 [Ralstonia pickettii 12D], gi|240866564|gb|AC...
 3.0E-49 [28..153] [1..125]
RR12_GUITH - 30S ribosomal protein S12, chloroplastic OS=Guillardia theta GN=rps12 PE=3 SV=1
 3.0E-49 [28..152] [1..123]
RS12_AQUAE - 30S ribosomal protein S12 OS=Aquifex aeolicus GN=rpsL1 PE=3 SV=1
RS12_AQUAE - 30S ribosomal protein S12 OS=Aquifex aeolicus (strain VF5) GN=rpsL1 PE=3 SV=1
 5.0E-49 [28..152] [1..124]
RS12_SPIPL - (P13576) 30S ribosomal protein S12
RS12_ARTPT - 30S ribosomal protein S12 OS=Arthrospira platensis GN=rpsL PE=3 SV=1
 5.0E-49 [28..151] [1..123]
gi|25294704 - gi|25294704|pir||AB3346 SSU ribosomal protein S12P [imported] - Brucella melitensis (strain 16M)
gi|17982691, gi|... - gi|17987035|ref|NP_539669.1| 30S ribosomal protein S12 [Brucella melitensis 16M], gi|17982691|gb|AAL...
 8.0E-49 [19..151] [3..134]
RR12_NASOF - 30S ribosomal protein S12, chloroplastic OS=Nasturtium officinale GN=rps12-A PE=3 SV=1
RR12_LEPVR - 30S ribosomal protein S12, chloroplastic OS=Lepidium virginicum GN=rps12-A PE=3 SV=1
gi|166065420, gi... - gi|189162334|ref|YP_001936496.1| ribosomal protein S12 [Fagopyrum esculentum subsp. ancestrale], gi|...
RR12_LOBMA - 30S ribosomal protein S12, chloroplastic OS=Lobularia maritima GN=rps12-A PE=3 SV=1
gi|160369876, gi... - gi|161622333|ref|YP_001586205.1| ribosomal protein S12 [Acorus americanus], gi|161622289|ref|YP_0015...
RR12_DRANE - 30S ribosomal protein S12, chloroplastic OS=Draba nemorosa GN=rps12 PE=3 SV=1
RR12_CUCSA - 30S ribosomal protein S12, chloroplastic OS=Cucumis sativus GN=rps12-A PE=3 SV=1
RR12A_OLIPU - 30S ribosomal protein S12-A, chloroplastic OS=Olimarabidopsis pumila GN=rps12-A PE=3 SV=1
RR12_NICSY - 30S ribosomal protein S12, chloroplastic OS=Nicotiana sylvestris GN=rps12-A PE=3 SV=1
RR12_PIPCE - 30S ribosomal protein S12, chloroplastic OS=Piper cenocladum GN=rps12-A PE=3 SV=1
RR12_NICTO - 30S ribosomal protein S12, chloroplastic OS=Nicotiana tomentosiformis GN=rps12-A PE=3 SV=1
RR12_ACOCL - 30S ribosomal protein S12, chloroplastic OS=Acorus calamus GN=rps12-A PE=3 SV=1
RR12_CRUWA - 30S ribosomal protein S12, chloroplastic OS=Crucihimalaya wallichii GN=rps12-A PE=3 SV=1
RR12_TOBAC - 30S ribosomal protein S12, chloroplastic OS=Nicotiana tabacum GN=rps12-A PE=1 SV=2
RR12_CAPBU - 30S ribosomal protein S12, chloroplastic OS=Capsella bursa-pastoris GN=rps12-A PE=3 SV=1
RR12_NICPL - 30S ribosomal protein S12, chloroplastic OS=Nicotiana plumbaginifolia GN=rps12 PE=1 SV=2
RR12_SPIOL - 30S ribosomal protein S12, chloroplastic OS=Spinacia oleracea GN=rps12-A PE=1 SV=2
RR12_ARATH - 30S ribosomal protein S12, chloroplastic OS=Arabidopsis thaliana GN=rps12-A PE=2 SV=2
RR12_BARVE - 30S ribosomal protein S12, chloroplastic OS=Barbarea verna GN=rps12-A PE=3 SV=1
RR12_AETCO - 30S ribosomal protein S12, chloroplastic OS=Aethionema cordifolium GN=rps12-A PE=3 SV=1
RR12_AETGR - 30S ribosomal protein S12, chloroplastic OS=Aethionema grandiflorum GN=rps12-A PE=3 SV=1
 9.0E-49 [28..151] [1..123]

Back

Predicted Domain #1
Region A:
Residues: [1-153] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRFMSNTW CTPLRQAQRL FSSTTTMQAT LNQIKRGSGP PRRKKISTAP QLDQCPQRKG  60
   61 VVLRVMVLKP KKPNSAQRKA CRVRLTNGNV VSAYIPGEGH DAQEHSIVYV RGGRCQDLPG 120
  121 VKYHVIRGAG DLSGVVNRIS SRSKYGAKKP SKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 326.522879
Match: 1l1uL_
Description: No description for 1l1uL_ was found.

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 7.45319063235379 bayes_pls_golite062009
structural molecule activity 6.87843523680097 bayes_pls_golite062009
misfolded RNA binding 4.4877915495248 bayes_pls_golite062009
nucleic acid binding 3.7132569326175 bayes_pls_golite062009
RNA binding 3.30183895019873 bayes_pls_golite062009
DNA binding 2.94486937698231 bayes_pls_golite062009
2.80746531284205 bayes_pls_golite062009
binding 2.40532042551671 bayes_pls_golite062009
mRNA binding 1.65819015373151 bayes_pls_golite062009
translation regulator activity 1.46320772716954 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.40718318783582 bayes_pls_golite062009
translation initiation factor activity 1.27539679024898 bayes_pls_golite062009
transcription regulator activity 1.24522359765541 bayes_pls_golite062009
protein binding 1.20309946451799 bayes_pls_golite062009
structure-specific DNA binding 1.10289736160471 bayes_pls_golite062009
single-stranded DNA binding 0.96886436248958 bayes_pls_golite062009
ribonuclease activity 0.91658673456122 bayes_pls_golite062009
transcription factor activity 0.672797026326101 bayes_pls_golite062009
transcription activator activity 0.581984534552921 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 0.474251377131502 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 0.47336621289748 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 0.47336621289748 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.438266295385131 bayes_pls_golite062009
exoribonuclease activity 0.39131721416336 bayes_pls_golite062009
sequence-specific DNA binding 0.3506031439435 bayes_pls_golite062009
nuclease activity 0.17660139576327 bayes_pls_golite062009
RNA polymerase activity 0.1542034177713 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.1542034177713 bayes_pls_golite062009
transcription factor binding 0.132487446755259 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.0717589400404304 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle