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Protein Overview: YKL027W

General Information:
Name(s) found: YKL027W [SGD]
Description(s) found:
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  • gi|6322825|ref|NP_012898.1| Protein of unknown function, localized to the mitochondrial outer membrane; Ykl027wp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|549663|sp|P36101.1|YKC7_YEAST RecName: Full=Uncharacterized protein YKL027W [NCBI NR]
  • pir||S37844 molybdopterin-converting factor homolog YKL027w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|486025|emb|CAA81862.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Uncharacterized protein YKL027W OS=Saccharomyces cerevisiae GN=YKL027W PE=1 SV=1 [Swiss-Prot]
  • Protein of unknown function localised to mitochondria [mips]
  • Protein of unknown function, localized to the mitochondrial outer membrane [SGD]
  • YKL027W, Chr XI from 387200-388543 [yeast_orfs2]
  • Chr XI from 387200-388543 [yeastorf3.fasta]
  • (P36101) Hypothetical 50.3 kDa protein in TFA1-PAN3 intergenic region [4932.FASTACCERV.txt]
  • YKL027W SGDID:S0001510, Chr XI from 387205-388548, Uncharacterized ORF [yeastflysequest.fasta]
  • Ykl027wp [Saccharomyces cerevisiae]gi|486025|emb|CAA81862.1| unnamed protein product [Saccharomyces cerevisiae]gi|539295|pir||S37844 molybdopterin-converting factor homolog YKL027w - yeast (Saccharomyces cerevisiae)gi|549663|sp|P36101|YKC7_YEAST Hypot [nrdb_11152004_Chlamydomonas]
  • YKL027W SGDID:S000001510, Chr XI from 387205-388548, Uncharacterized ORF, "Putative protein of unknown function; detectable in highly purified mitochondria" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YKL027W SGDID:S000001510, Chr XI from 387205-388548, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane" [yeast-contam.fasta]
  • Uncharacterized protein YKL027W [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein of unknown function, localized to the mitochondrial outer membrane; Ykl027wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Uncharacterized protein YKL027W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YKL027W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YKL027W SGDID:S000001510, Chr XI from 387562-388905, Genome Release 64-1-1, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane" [yeast-030211-contam.fasta]
  • TCD2 SGDID:S000001510, Chr XI from 387562-388905, Genome Release 64-2-1, Verified ORF, "tRNA threonylcarbamoyladenosine dehydratase; required for the ct6A tRNA base modification, where an adenosine at position 37 is modified to form a cyclized active ester with an oxazolone ring; localized to the mitochondrial outer membrane; TCD2 has a paralog, TCD1, that arose from the whole genome duplication" [20141208_orf_trans.fasta]
  • TR3197|c0_g1_i1|g.2289 ORF TR3197|c0_g1_i1|g.2289 TR3197|c0_g1_i1|m.2289 type:complete len:448 (+) TR3197|c0_g1_i1:443-1786(+) [Y12_S_cerevisiae-Sep2015-contam.fasta]
  • TR1936|c0_g1_i1|g.1348 ORF TR1936|c0_g1_i1|g.1348 TR1936|c0_g1_i1|m.1348 type:complete len:448 (+) TR1936|c0_g1_i1:442-1785(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta]
  • asmbl_6617|g.5081 ORF asmbl_6617|g.5081 asmbl_6617|m.5081 type:complete len:448 (+) asmbl_6617:664-2007(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta]
  • asmbl_6695|g.4866 ORF asmbl_6695|g.4866 asmbl_6695|m.4866 type:complete len:448 (+) asmbl_6695:1926-3269(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta]
  • ID=asmbl_6847,ID=asmbl_6848|g.4187 ORF ID=asmbl_6847,ID=asmbl_6848|g.4187 ID=asmbl_6847,ID=asmbl_6848|m.4187 type:complete len:448 (+) ID=asmbl_6847,ID=asmbl_6848:1853-3196(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
  • ID=asmbl_6714|g.4043 ORF ID=asmbl_6714|g.4043 ID=asmbl_6714|m.4043 type:complete len:448 (+) ID=asmbl_6714:1926-3269(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 447 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEKDTWKLI TATALFTVAV TTITDYAWTS WQAQKQVIAQ QKNKNKGGQT KSDTDKYHQY  60
   61 DEQFIRQSLK NNVEFLGEDT IEKLSNQYVV VVGAGGVGSW VVNSLVRSGC RKIRVVDFDQ 120
  121 VSLSSLNRHS CAILNDVGTP KVECLRRHMR EIAPWCEIDP INELWTLQNG ERLTLGNGTP 180
  181 DFIVDCIDNI DTKVDLLEFA YNHGIKVISS MGASAKSDPT KLNVGDLATT EEDPLARVVR 240
  241 RKLKKRGILS GIPVVFSAEK PDPKKAKLLP LPDEEYERGK VDELSALKDF RVRILPVLGT 300
  301 MPSLFGLTIT TWILSNISDK PLEPVEGKNR IKVYDGIYQS LAGQMSRVGI PSQRIPLALK 360
  361 DVSYLVEEVF KGKSPISGIS TRLTLTKWDP SKPISLQNVV VLTKNEQKVH EDRVLKGKES 420
  421 LQDVYDAKVL KLVSQRFREE AYYSQFR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CSI1 CSN9 ERV46 FPR2 HUL5 IQG1 MOT1 MPT5 NAS6 NMD3 NPT1 PCI8 PEP1 PST1 PUS9 RPN1 RPN10 RPN11 RPN12 RPN13 RPN14 RPN2 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 RRI1 RRI2 SEC18 SEM1 SKP1 SPG5 SPO77 SQT1 SWA2 TCB2 TIP41 TOD6 TOR2 TSR4 UBP6 YEN1 YKL027W YMR258C YNL022C YPR003C YPT52

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YKL027W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..372] PSI-BLAST 179.154902 Molybdenum cofactor biosynthesis protein MoeB
    2 View Details [373..447] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.22201444897049 bayes_pls_golite062009
  • small protein activating enzyme activity
    		•  1.15794018549551 bayes_pls_golite062009
  • ligase activity
    		•  0.886082936938522 bayes_pls_golite062009
  • URM1 activating enzyme activity
    		•  0.713014667868835 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.638417722038888 bayes_pls_golite062009
  • binding
    		•  0.638109912495373 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.298620408596939 bayes_pls_golite062009
  • protein binding
    		•  0.108982876084282 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle