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View Structure Prediction Details

Protein: YKL027W
Organism: Saccharomyces cerevisiae
Length: 447 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKL027W.

Description E-value Query
Range		 Subject
Range
YKL027W - Protein of unknown function, localized to the mitochondrial outer membrane
TCD2_YEAST - tRNA threonylcarbamoyladenosine dehydratase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
 0.0 [1..447] [1..447]
SPAC1A6.10 - Moeb /ThiF domain
TCD_SCHPO - tRNA threonylcarbamoyladenosine dehydratase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
 2.0E-93 [19..438] [61..476]
UBA1_MOUSE - Ubiquitin-like modifier-activating enzyme 1 OS=Mus musculus GN=Uba1 PE=1 SV=1
 9.0E-72 [10..248] [396..638]
UBA1_RABIT - Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus cuniculus GN=UBA1 PE=1 SV=1
 2.0E-71 [10..248] [396..638]
gi|24485 - gi|24485|emb|CAA37078.1| unnamed protein product [Homo sapiens]
 8.0E-71 [10..248] [141..383]
CG13090-PA, FBpp... - This gene is referred to in FlyBase by the symbol Dmel\CG13090 (CG13090, FBgn0032054). It is a prote...
 1.0E-68 [17..385] [11..339]

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Predicted Domain #1
Region A:
Residues: [1-372] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEKDTWKLI TATALFTVAV TTITDYAWTS WQAQKQVIAQ QKNKNKGGQT KSDTDKYHQY  60
   61 DEQFIRQSLK NNVEFLGEDT IEKLSNQYVV VVGAGGVGSW VVNSLVRSGC RKIRVVDFDQ 120
  121 VSLSSLNRHS CAILNDVGTP KVECLRRHMR EIAPWCEIDP INELWTLQNG ERLTLGNGTP 180
  181 DFIVDCIDNI DTKVDLLEFA YNHGIKVISS MGASAKSDPT KLNVGDLATT EEDPLARVVR 240
  241 RKLKKRGILS GIPVVFSAEK PDPKKAKLLP LPDEEYERGK VDELSALKDF RVRILPVLGT 300
  301 MPSLFGLTIT TWILSNISDK PLEPVEGKNR IKVYDGIYQS LAGQMSRVGI PSQRIPLALK 360
  361 DVSYLVEEVF KG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 179.154902
Match: 1jw9B_
Description: Molybdenum cofactor biosynthesis protein MoeB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.22201444897049 bayes_pls_golite062009
small protein activating enzyme activity 1.15794018549551 bayes_pls_golite062009
ligase activity 0.886082936938522 bayes_pls_golite062009
URM1 activating enzyme activity 0.713014667868835 bayes_pls_golite062009
transcription regulator activity 0.638417722038888 bayes_pls_golite062009
binding 0.638109912495373 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.298620408596939 bayes_pls_golite062009
protein binding 0.108982876084282 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [373-447] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSPISGISTR LTLTKWDPSK PISLQNVVVL TKNEQKVHED RVLKGKESLQ DVYDAKVLKL  60
   61 VSQRFREEAY YSQFR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle